POLARISCOPIC EXAMINATION OF GLASS CONTAINER SECTIONS*

The ring-section technique has been studied by the Standard Testing Procedure Committee of the Glass Container Association, and a tentative Standard Method of Examining and Grading Glass Container Ring Sections is proposed. The scope, method, and frequency of sampling, method of examination, and the methods used for ware-quality grading and glass-quality grading are described.     

EFFECT OF BARIUM OXIDE AND ZINC OXIDE ON PROPERTIES OF SODA-DOLOMITE LIME-SILICA GLASS*

To a base glass containing 14% of sodium oxide, 12% of dolomite lime, and 74% of silica, barium oxide and zinc oxide, respectively, were systematically substituted for (a) Na₂O, (b) CaO.MgO, and (c) SiO₂ in amounts of 1, 3, and 5%. The effects of these substitutions on such physical properties as liquidus temperature, viscosity, deformation temperature, density, fiber softening point, coefficient of expansion, and the resistance of the glasses to dilute acid and distilled water are presented.     

A best practice process model for hybrid concrete construction

The term ‘hybrid concrete construction’ (HCC) is used to describe the combination of concrete construction methods, e.g. in‐situ concrete and precast concrete, with one another or with other materials, e.g. steel. Although it could be argued that most buildings employ such combinations, HCC is the deliberate integration of different construction techniques to achieve a cost, speed or other performance benefit. UK government has been concerned that the construction industry suffers from poor management and exchange of tacit knowledge which can disappear after project teams ‘break up’. The completion of several innovative and high profile HCC projects was considered to be a major opportunity to capture project teams' tacit knowledge in this area. The objective of the research was to compile a best practice process model, such that project teams could be better informed as to their roles and responsibilities and thus be better equipped to deliver a building to the client's satisfaction, by using HCC. Interviews and knowledge capture workshops were used to extract lessons that lay embedded in both individuals and teams. The main conclusions were that successful HCC projects were characterized for example, by the development of an ethos of trust, the early involvement of specialists (such as precasters) and the effective management of both tacit and explicit knowledge. The research builds on previous work in the area by identifying best practice information on design, specification and construction factors for HCC and, in addition, some transferable lessons on knowledge capture techniques.     

Structural frame selection: case studies of hybrid concrete frames

Hybrid concrete construction (HCC) uses a combination of in-situ and precast concrete and is an example of ‘mixed’ construction, which is the term for an innovative combination of different materials or framing methods. Examples of HCC exist in many countries to fulfil varying structural requirements, so it is not clear why HCC is not better used in the UK. Research was undertaken to gain a better understanding of the selection and use of HCC. Two case study projects were investigated to explore decision-making criteria, the roles of project participants and the challenges particular to HCC. The findings suggest that HCC is selected when measurable cost or programme advantages are not the most important criteria, but where other factors such as satisfying architectural requirements (finish, colour, etc.) or operational demands (such as internal comfort or maintenance) are critical. In both cases, clients and architects were found to be the most influential team members in the frame-selection process.

La construction en béton hybride (HCC) utilise une combinaison de béton in situ et de béton précoulé; c'est un exemple de ‘construction mixte’; cette expression définit une combinaison innovante de différents matériaux et méthodes de coffrage. Il existe des exemples de HCC dans de nombreux pays qui répondent à différentes exigences structurales; on peut donc difficilement expliquer pourquoi la HCC n'est pas mieux utilisée au Royaume-Uni. Des recherches ont été entreprises pour mieux comprendre les choix et les usages de la HCC. Deux études de cas ont été engagées, l'objectif étant d'explorer les critères décisionnels, le rôle des participants à ces projets et les défis particuliers propres à la HCC. Les résultats laissent à penser que la HCC est retenue lorsque le coût mesurable ou les avantages du programme ne sont pas les critères les plus importants et lorsque d'autres facteurs comme la réponse aux exigences architecturales (finition, couleur, etc.) ou d'autres exigences opérationnelles (comme le confort intérieur ou la maintenance) sont critiques. Dans les deux cas, les clients et les architectes sont apparus comme les membres les plus influents des équipes lors du processus de sélection du cadre.

Mots clés: processus de conception, construction en béton hybride, construction mixte, critères de performances, cadre structural     

Comparison of Different Mass Spectrometry Workflows for the Proteomic Analysis of Tear Fluid

The tear film is a multi-layer fluid that covers the corneal and conjunctival epithelia of the eye and provides lubrication, nutrients, and protection from the outside environment. Tear fluid contains a high concentration of proteins and has thus been recognized as a potential source of biomarkers for ocular disorders due to its proximity to disease sites on the ocular surface and the non-invasive nature of its collection. This is particularly true in the case of dry eye disease, which directly impacts the tear film and its components. Proteomic analysis of tear fluid is challenging mainly due to the wide dynamic range of proteins and the small sample volumes. However, recent advancements in mass spectrometry have revolutionized the field of proteomics enabling unprecedented depth, speed, and accuracy, even with small sample volumes. In this study using the Orbitrap Fusion Tribrid mass spectrometer, we compared four different mass spectrometry workflows for the proteomic analysis of tear fluid collected via Schirmer strips. We were able to establish a method of in-strip protein digestion that identified >3000 proteins in human tear samples from 11 healthy subjects. Our method offers a significant improvement in the number of proteins identified compared to previously reported methods without pooling samples.