Long-term progression in chronic manganism: ten years of follow-up

We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 +/- 4.2 in 1987 to 28.3 +/- 6.70 in 1991 and then to 38.1 +/- 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure.     

Child abuse in Hong Kong revisited after 15 years: characteristics of victims and abusers

The purpose of this paper was to examine the characteristics of the victims and abusers of child abuse cases on the Child Protection Registry in Hong Kong as of March 1995 and to compare findings with a similar community report of child abuse in Hong Kong conducted approximately 15 years earlier. As of March 31, 1995, there were 457 active cases of child abuse or suspected child abuse (44% male and 56% female) on the computerized Child Protection Registry. Fifty percent of the victims were grade school age children between 7-12, and 62.4% suffered physical abuse. The abusers or suspected abusers were 52% male and 48% female with nearly half (49%) in their thirties. The majority of abusers were married/cohabiting (75%) with only a grade school education (60%). As compared to 1979, there was an increase of sexual child abuse cases, female victims of child abuse, and an increase in male abusers or suspected abusers.     

Scalar quantisation of LSF parameters using vector measurement

A new form of line spectral frequency (LSF), bounded line spectral frequency, is presented. It is shown that the new representation is more efficient than the direct line spectral frequency and the differential line spectral frequency (DLSF). By using a vector measure, the scalar quantisation of tenth-order linear predictive coding (LPC) parameters can be coded at 28 bit/frame with a transparent quantisation quality     

Variants of chromosome 9 in phenotypically normal individuals

The human chromosome 9 displays the highest degree of structural variability. Four different types of variants are described including pericentric inversion, extra G-positive band in the q arm, additional G-positive band in the p arm and duplication of band 9q21-q22. It is important to demonstrate inheritance from a phenotypically normal individual in order to differentiate between a variant chromosome and an abnormal chromosome.     

Improved strained HEMT characteristics using double-heterojunctionIn0.65Ga0.35As/In0.52Al0.48As design

The DC and microwave properties of strained In_0.65Ga _0.35As/In₀₅₂Al_0.48As HEMTs (high electron-mobility transistors) with double-heterojunction design are presented. The high sheet carrier density and good carrier confinement give rise to excellent device performance with very low output conductance. For 1×150-μm² long-gate HEMTs, the measured cutoff frequency f_T and maximum frequency of oscillation f_max are as high as 37 and 66 GHz, respectively     

Determination of alpha-particle track depths in CR-39 detector from their cross-sections and replica heights

A challenging task in the application of solid-state nuclear track detectors (SSNTDs) is the measurement of depths of the tracks. One approach involves breaking and polishing the side of SSNTDs to reveal the cross-sections of the tracks for direct measurements. Recently, surface profilometry was used to measure the heights of the replicas of alpha-particle tracks to give the track depths. In the present work, systematic comparisons among the track depths for alpha-particles with normal incidence and different incident energies were made for these two methods. After irradiation, the detectors were etched in a 6.25 N aqueous solution of NaOH at 70 °C. Both long etching time of 15 h (to produce spherical-phase tracks) and short etching time from 1 to 8 h (to produce sharp-phase tracks) were used. Good agreement was achieved between the two methods for spherical-phase tracks but not for sharp-phase tracks. It has been found that the surface profilometry method only works for replicas for spherical-phase tracks. Replicas for sharp-phase tracks are easier to collapse or deform, so the surface profilometry method may not give correct results.     

Frontoethmoidal meningoencephaloceles: a review of 14 consecutive patients

Over a period of 4.5 years, 14 patients with frontoethmoidal meningoencephaloceles were treated. Most patients came from Northern Namibia. Precise delineation of all cranial abnormalities was obtained by modern imaging techniques, and specific patterns of cerebral abnormality were found. The malformation was corrected in a single stage, and significant modifications have been developed to render the procedure simpler and safer. Information from our series favors delayed neural tube closure as the primary pathogenesis of the defect and suggests a common teratogen as the most probable etiological agent. Our experience leads us to advocate early correction of even small defects.     

Optical appearance of alpha particle tracks in CR-39 SSNTD

A ray tracing method based on geometrical optics was used to study the tracks from alpha particles with different energies and with an incident angle of 50°. The transmission operation mode of the microscope is simulated. Considering the distribution of light intensities from the tracks, the mean and the 80% percentile gray levels from real experiments are proposed as quantitative variables to differentiate among tracks. The gray level properties for the same track for different exposures can vary to large extents. We introduce three variables, κ, λ and ε, to make empirical corrections. It is interesting to see that these coefficients are very consistent for the same alpha particle track despite the very different gray level properties. Gray level results have been obtained for tracks from alpha particles with 50° incident angle and different incident energies. However, the track depths cannot be predicted by any one of the coefficients κ, λ and ε. Multivariate analyses can help separate the tracks corresponding to different alpha energies. By using discriminant analysis with κ, λ and ε as independents, effectively all alpha energies can be determined with an accuracy of ±0.5 MeV.