改扩建水库土坝段三维渗流问题仿真研究

渗流问题是直接影响大坝改扩建后运行安全的关键问题,为此,利用三维渗流场的仿真研究,合理评价大坝改扩建设计渗控的合理性和有效性是十分必要的。采用无压渗流场仿真计算理论和有限元方法,在设计渗控措施下,对某水库加高加固后土坝的三维渗流问题进行仿真计算,并定性、定量分析了土坝坝区浸润线、水头分布、渗透坡降及渗漏量等渗流参数的数值规律。结果表明,混凝土预制块、复合土工膜、防渗帷幕等组成的坝体防渗体系,可以有效地截断通过土坝的渗流,但水库水位的抬高也增加了土坝连接部位的绕渗、渗透坡降等不利渗流的安全问题。     

浅谈大同市排水管网的改造

结合大同市的城市排水规划,指出对现状欠合理的城市排水管网进行改造,是城市发展过程中不可回避的问题,针对这些现状排水管网,文中阐述了对其改造的一些建议和方案,以实现城市排水管网的合理性,促进其建设的可持续发展.     

猪肉组织的近场太赫兹成像检测研究

利用搭建的基于光电导微探针的近场太赫兹(Terahertz,THz)系统对新鲜猪肉组织切片进行了成像检测研究,结果发现近场THz成像可以很好地区分猪肉组织中的脂肪组织区域和肌肉组织区域,其成像效果明显优于传统远场THz时域光谱成像系统。研究表明了基于光电导微探针的近场THz成像技术在生物样品检测方面的可行性,展示出该技术在生物医学检测领域具有很好的应用前景。     

疲劳断裂过程中渗碳层残余奥氏体的转变

研究了20CrNiMo钢微氮渗碳层中残余奥氏体的形态,及其在疲劳断裂过程中的转变和作用。结果表明:渗碳层残余奥氏体有薄膜状和块状两种形态,由于界面取向的影响,疲劳裂纹更易于穿过块状奥氏体,促使其发生应变诱发马氏体相变。在疲劳断裂过程中,裂纹面附近的残余奥氏体大部分转变成马氏体,这种转变是在断裂瞬间发生的,与疲劳力学条件无关。转变所引起的体积膨胀增强了裂纹闭合效应。相变诱发闭合是渗碳表层高碳区疲劳裂纹扩张行为的主要因素之一。     

Intracellular routes and selective retention of antigens in mildly acidic cathepsin D/lysosome-associated membrane protein-1/MHC class II-positive vesicles in immature dendritic cells

Immature dendritic cells (DC) use both macropinocytosis and mannose receptor-mediated endocytosis to internalize soluble Ags efficiently. These Ags are ultimately presented to T cells after DC maturation and migration into the lymph nodes. We have previously described the immortalized myeloid cell line FSDC as displaying the characteristics of early DC precursors that efficiently internalize soluble Ags. To describe the different routes of Ag uptake and to identify the Ag retention compartments in FSDC, we followed the intracellular fate of FITC-coupled OVA, dextran (DX), transferrin, and Lucifer Yellow using flow cytometry, confocal microscopy, and immunoelectron microscopy. OVA and DX gained access into macropinosomes and early endosomes. DX was preferentially sorted into endosomal compartments, while most of the OVA entered macropinosomes via fluid phase uptake. We found a long-lasting retention of DX and OVA of up to 24 h. After 6 h of chase, these two molecules were concentrated in common vesicular compartments. These retention compartments were distinct from endosomes and lysosomes; they were much larger, only mildly acidic, and lacked the small GTP binding protein rab7. However, they were positive for lysosome-associated membrane protein-1, the protease cathepsin D, and MHC class II molecules, thus representing matured macropinosomes. These data suggest that the activity of vacuolar proteases is reduced at the mildly acidic pH of these vesicles, which explains their specific retention of an Ag. The retention compartments might be used by nonlymphoid tissue DC to store peripheral Ags during their migration to the lymph node.     

Deferoxamine in thalassemia major

The evolution of women's health both in the United States and abroad is a direct result of an intense commitment to scientific investigation and education. Society serves to benefit greatly from this global effort.     

利用辐射壁提高燃油锅炉热效率的研究

针对一台立式燃油热水锅炉的结构特点,设计了在炉膛安装燃烧反应器对锅炉进行节能改造的方案,通过流体计算软件Fluent 对锅炉改造前后的燃烧换热状况进行了数值计算,并进行了锅炉改造前后热平衡对比试验,数值计算和试验结果基本一致.改造后提高了炉膛辐射换热量,增加了热烟气在炉内的停留时间,改变了原来锅炉炉膛受热不均的状况,换...