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131.
Volumetric positional accuracy constitutes a large portion of the total machine tool error during machining. In order to improve machine tool accuracy cost-effectively, machine tool geometric errors as well as thermally induced errors have to be characterized and predicted for error compensation. This paper presents the development of kinematic error models accounting for geometric and thermal errors in the Vertical Machining Center (VMC). The machine tool investigated is a Cincinnati Milacron Sabre 750 3 axes CNC Vertical Machining Center with open architecture controller. Using Rigid Body Kinematics and small angle approximation of the errors, each slide of the three axes vertical machining center is modeled using homogeneous coordinate transformation. By synthesizing the machine's parametric errors such as linear positioning errors, roll, pitch and yaw etc., an expression for the volumetric errors in the multi-axis machine tool is developed. The developed mathematical model is used to calculate and predict the resultant error vector at the tool–workpiece interface for error compensation.  相似文献   
132.
Abnormality in glucose homeostasis due to hyperglycemia or insulin resistance is the hallmark of type 2 diabetes mellitus (T2DM). These metabolic abnormalities in T2DM lead to cellular dysfunction and the development of diabetic cardiomyopathy leading to heart failure. New antihyperglycemic agents including glucagon-like peptide-1 receptor agonists and the sodium–glucose cotransporter-2 inhibitors (SGLT2i) have been shown to attenuate endothelial dysfunction at the cellular level. In addition, they improved cardiovascular safety by exhibiting cardioprotective effects. The mechanism by which these drugs exert their cardioprotective effects is unknown, although recent studies have shown that cardiovascular homeostasis occurs through the interplay of the sodium–hydrogen exchangers (NHE), specifically NHE1 and NHE3, with SGLT2i. Another theoretical explanation for the cardioprotective effects of SGLT2i is through natriuresis by the kidney. This theory highlights the possible involvement of renal NHE transporters in the management of heart failure. This review outlines the possible mechanisms responsible for causing diabetic cardiomyopathy and discusses the interaction between NHE and SGLT2i in cardiovascular diseases.  相似文献   
133.
The main aim of this investigation is to discover the effects of clearance parameters on the steady-state heat transfer. In order to solve the three-dimensional elliptic governing equations, a finite volume based CFD code was used. The clearance gap between fin tips and shroud, the base and fin temperatures and the size and configuration of the finned surfaces were varied during the parametric study. The numerical results have been compared to existing experimental values from the literature and the comparison shows a good agreement. It is found that the heat transfer coefficient increases with the increase in the clearance parameter and it approaches to the value of heat transfer coefficient obtained for unshrouded fin arrays.  相似文献   
134.
Satellite networks are used as backup networks to the terrestrial communication systems. In this work, we tried to find a routing strategy over dynamic satellite systems to better utilize the capacity of the network. The satellite networks are not affected by natural disasters, therefore they can be used widely during and after disasters. The Minimum Flow Maximum Residual (MFMR) routing algorithm over the Routing Set boundaries is proposed in order to better utilize the capacity of the system by distributing the load over the shortest path alternatives of the system. We assumed the satellite network as having finite states and formulated the problem by using Finite State Automation concept along with earth-fixed cell strategy by using a virtual satellite network model. The routing problem in satellite networks is previously studied in the literature and it is conjectured that the problem is NP-Hard. The online and offline problems are stated and the MFMR algorithm is described in detail. The algorithm is compared with alternatives by simulating the network on Opnet Modeler. Finally, the performance analysis of different scenarios is given in this work. Roy Kucukates received his BS, MS and PhD degrees in computer engineering from Bogazici University, Istanbul, in 1993, 1995 and 2002, respectively. He worked as teaching assistant in Bogazici University between 1993 and 1995. Currently, he is a part time instructor in the Computer Engineering Department of Koc University and Dogus University. He is the co-founder and manager of Gordion Bilgi Hizmet Ltd Sti. LEO satellite networks, wireless networks, simulation and performance evaluationl, routing protocols can be stated among his research areas. Cem Ersoy received his BS and MS degrees in electrical engineering from Bogazici University, Istanbul, in 1984 and 1986, respectively. He worked as an R&D engineer in NETAS A.S. between 1984 and 1986. He received his PhD in electrical engineering from Polytechnic University, Brooklyn, New York in 1992. Currently, he is a professor and department head in the Computer Engineering Department of Bogazici University. His research interests include performance evaluation and topological design of communication networks, wireless communications and mobile applications. Wireless sensor networks. Dr. Ersoy is a Senior Member of IEEE.  相似文献   
135.
The Poly(4-vinyl phenol) insulator layer was grown by spin coating technique onto p-Si substrate. Diode ideality factor (n), insulator layer thickness (δ), space charge region width (WD), interface state density (Nss), series resistance (Rs), acceptor concentration (NA) of the Au/Poly(4-vinyl phenol)/p-Si structure have been extracted from the current–voltage (IV), frequency dependent capacitance–voltage (CV) and conductance–voltage (GV) measurements. It is pointed out that the interface states lead to deviation of the ideality factor value from 1 and frequency dispersion of the CV characteristics. Nss profiles as a function of (EssEv) obtained using IV and low frequency CV measurements are in good agreement. Nss values varying between 1012 and 1013 eV−1 cm−2 mean that Poly(4-vinyl phenol) is a candidate for insulator layer forming on Si as powerful as SiN4, SnO2, TiO2.  相似文献   
136.
We consider detection of moving ground vehicles in airborne sequences recorded by a thermal sensor with automatic gain control, using an approach that integrates dense optic flow over time to maintain a model of background appearance and a foreground occlusion layer mask. However, the automatic gain control of the thermal sensor introduces rapid changes in intensity that makes this difficult. In this paper we show that an intensity-clipped affine model of sensor gain is sufficient to describe the behavior of our thermal sensor. We develop a method for gain estimation and compensation that uses sparse flow of corner features to compute the affine background scene motion that brings pairs of frames into alignment prior to estimating change in pixel brightness. Dense optic flow and background appearance modeling is then performed on these motion-compensated and brightness-compensated frames. Experimental results demonstrate that the resulting algorithm can segment ground vehicles from thermal airborne video while building a mosaic of the background layer, despite the presence of rapid gain changes.  相似文献   
137.
Effects of ochratoxin A on micronucleus frequency in human lymphocytes   总被引:2,自引:0,他引:2  
Ochratoxin A (OTA), a nephrotoxic and carcinogenic mycotoxin, was investigated to examine its potency to induce micronuclei (MN) in cultured human lymphocytes. Lymphocyte cultures were treated for the last 48 h with OTA at concentrations of 25 microM, 10 microM, 1 microM, 100 nM, 10 nM, 1 nM, and 100 microM and absolute ethanol. At the highest concentration, OTA was found to induce MN in cytokinesis-blocked lymphocytes (p < 0.05). The 25 microM OTA concentration also led to a clear decrease in the percentage of binucleated cells, probably due to cytotoxicity. OTA at the other concentrations tested did not induce MN frequency. These results indicate that a high concentration of OTA is genotoxic in cultured human lymphocytes.  相似文献   
138.
139.
When wireless sensors are used to keep an area under surveillance, a critical issue is the quality of the deployment from the sensing coverage viewpoint. In this paper, we propose several quality measures, which indicate if the deployment provides sufficient coverage, or whether redeployment is required or not. The terrain is modeled as a grid and the placement of the sensors is uniformly distributed. Neyman–Pearson detection is utilized to determine the effects of false-alarm and signal characteristics on the measures.  相似文献   
140.
Today's commercial satellite images enable experts to classify region types in great detail. In previous work, we considered discriminating rural and urban regions. However, a more detailed classification is required for many purposes. These fine classifications assist government agencies in many ways including urban planning, transportation management, and rescue operations. In a step toward the automation of the fine classification process, this paper explores graph theoretical measures over grayscale images. The graphs are constructed by assigning photometric straight-line segments to vertices, while graph edges encode their spatial relationships. We then introduce a set of measures based on various properties of the graph. These measures are nearly monotonic (positively correlated) with increasing structure (organization) in the image. Thus, increased cultural activity and land development are indicated by increases in these measures - without explicit extraction of road networks, buildings, residences, etc. These latter, time consuming (and still only partially automated) tasks can be restricted only to "promising" image regions, according to our measures. In some applications our measures may suffice. We present a theoretical basis for the measures followed by extensive experimental results in which the measures are first compared to manual evaluations of land development. We then present and test a method to focus on, and (pre)extract, suburban-style residential areas. These are of particular importance in many applications, and are especially difficult to extract. In this work, we consider commercial IKONOS data. These images are orthorectified to provide a fixed resolution of 1 meter per pixel on the ground. They are, therefore, metric in the sense that ground distance is fixed in scale to pixel distance. Our data set is large and diverse, including sea and coastline, rural, forest, residential, industrial, and urban areas.  相似文献   
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