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61.
Conducted interviews with 39 psychologists and psychology students to examine attitudes toward reporting child abuse cases to the authorities. Ss were almost equally divided in their decisions about reporting; the majority considered the child's life the most important, with confidentiality ranked second, and the law ranked third. Those who considered the law the most important issue (31%) chose always to report the abuse. Those who considered the law the least important issue (41%) saw the spirit of the law as more important than the letter and based their decision on their perception of the consequences for the child. (9 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
62.
Health, leisure and beauty activities are increasing in popularity, with a particular emphasis on self-help and alternative health practices. One product type that has increased sales with this expansion is the hand-held electric massager. These are products that use vibration as a means of alleviating muscular strains and pains, as well as promoting relaxation. Paradoxically, these products are extremely popular as gifts, but are soon discarded. A multi-disciplinary research team was commissioned by a British manufacturer of electrical consumer products to investigate user attitudes and perceptions of existing massagers, to identify areas of user dissatisfaction. The manufacturer was also concerned about a possible stigma attached to these products because of an association with sex aids. This paper provides an account of the perceptions of both consumers and therapists regarding the use of these products. Identifying the differences between the perceptions of consumers and therapists should help provide a basis for effective integration of user needs, manufacturer requirements, designers' skills and sound therapeutic practice. The results provide insight to support the development of more effective hand-held massagers. 相似文献
63.
82 preschoolers' (40–62 mo old) rates of behavior were observed toward play activities (e.g. dolls, trucks) and teacher-related variables. Results show that both sexes increased rates of participation in response to teacher presence in male and female sex-typed activity areas during free play. Girls, however, responded more consistently to teacher presence than did boys, who modulated their responses according to both the sex typing of the activity and the sex of the teacher. Findings indicate that typically observed teacher behavior during free play may contribute significantly to reported patterns of sex-differentiated play. (13 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
64.
The U.S. Geological Survey produces a variety of resource information for the United States. This includes many data bases of particular interest to planners such as land use and terrain information prepared by the National Mapping Division, water quantity and quality data collected by Water Resources Division, and coal resource information gathered by the Geologic Division. These data are stored in various forms, and information on their availability can be obtained from appropriate offices in the U.S. Geological Survey as well as from USGS Circular 777. These data have been used for the management, development, and monitoring of our Nation's resources by Federal, State, and local agencies. 相似文献
65.
Paul Schissel Gary Jorgensen Cheryl Kennedy Rita Goggin 《Solar Energy Materials & Solar Cells》1994,33(2)
Metallized, flexible polymeric reflector materials are much lighter and potentially less expensive than the conventional glass/metal mirrors often used in solar thermal concentrators such as heliostats and parabolic dishes and troughs. Unweathered silvered-PMMA reflectors have a solar reflectance at least as high as glass reflectors, but their environmental durability needs to be demonstrated. ECP-305, a silvered-PMMA film available commercially from the 3M Company and developed in collaboration with the National Renewable Energy Laboratory, is the current state of the art. Important progress has been made in overcoming the three primary mechanisms causing ECP-305 to lose reflectance. These mechanisms are: (1) photon-induced silver corrosion, (2) surface soiling, and (3) a form of delamination called tunneling. Given the progress in resolving these performance lifetime issues, silvered-PMMA films should meet the reflectance and durability goals. 相似文献
66.
Peter MA Toivonen Paul A Wiersma Cheryl Hampson Brenda Lannard 《Journal of the science of food and agriculture》2010,90(4):580-585
BACKGROUND: One of the realities of apple distribution for long‐term stored fruit is that a controlled‐atmosphere (CA) storage room will be unsealed and fruit held in air storage and marketed over several weeks. This work was conducted to determine the effect of post‐CA air storage of whole fruit on potential shelf life for fresh‐cut apple slices. RESULTS: Fresh‐cut slices of ‘Spartan’ and ‘Delicious’ apples held in post‐CA air storage for 2 or 4 weeks showed the least changes in cut surface color as compared with those made from apples immediately on removal from CA. Shelf life was most improved by post‐CA air storage in the ‘Spartan’ apples, which were more advanced in maturity as compared with the ‘Delicious’ apples. Internal ethylene concentration, firmness, and respiration changed significantly with post‐CA air storage, suggesting a relationship between physiological status of the whole fruit and shelf life of slices made from that fruit. CONCLUSION: The results support the hypothesis that apples had suppressed physiological activity in CA storage and are susceptible to accelerated deterioration upon cutting. Holding fruit for 2 weeks in air storage allowed recovery of physiological activity, which resulted in greater resistance to deterioration in response to fresh‐cut processing. Copyright © 2010 Crown in the right of Canada. Published by JohnWiley & Sons, Ltd 相似文献
67.
AbstractThe KRYPTOS competition is an annual codebreaking competition for undergraduates. Debuting in 2011 with 49 participants from three states, after nine years we have seen over 1,000 students from 32 states and seven different countries. KRYPTOS will hold its tenth competition in April of 2020. Here we present some of the puzzles participants have found most elusive and challenge you to beat the clock on our fastest solver. 相似文献
68.
Front Cover: [Carboxyl‐11C]Labelling of Four High‐Affinity cPLA2α Inhibitors and Their Evaluation as Radioligands in Mice by Positron Emission Tomography (ChemMedChem 2/2018) 下载免费PDF全文
69.
[Carboxyl‐11C]Labelling of Four High‐Affinity cPLA2α Inhibitors and Their Evaluation as Radioligands in Mice by Positron Emission Tomography 下载免费PDF全文
Dr. Martin J. Fisher Dr. Lindsay McMurray Dr. Shuiyu Lu Cheryl L. Morse Dr. Jeih‐San Liow Dr. Sami S. Zoghbi Aneta Kowalski George L. Tye Dr. Robert B. Innis Prof. Franklin I. Aigbirhio Dr. Victor W. Pike 《ChemMedChem》2018,13(2):138-146
Cytosolic phospholipase A2α (cPLA2α) may play a critical role in neuropsychiatric and neurodegenerative disorders associated with oxidative stress and neuroinflammation. An effective PET radioligand for imaging cPLA2α in living brain might prove useful for biomedical research, especially on neuroinflammation. We selected four high‐affinity (IC50 2.1–12 nm ) indole‐5‐carboxylic acid‐based inhibitors of cPLA2α, namely 3‐isobutyryl‐1‐(2‐oxo‐3‐(4‐phenoxyphenoxy)propyl)‐1H‐indole‐5‐carboxylic acid ( 1 ); 3‐acetyl‐1‐(2‐oxo‐3‐(4‐(4‐(trifluoromethyl)phenoxy)phenoxy)propyl)‐1H‐indole‐5‐carboxylic acid ( 2 ); 3‐(3‐methyl‐1,2,4‐oxadiazol‐5‐yl)‐1‐(2‐oxo‐3‐(4‐phenoxyphenoxy)propyl)‐1H‐indole‐5‐carboxylic acid ( 3 ); and 3‐(3‐methyl‐1,2,4‐oxadiazol‐5‐yl)‐1‐(3‐(4‐octylphenoxy)‐2‐oxopropyl)‐1H‐indole‐5‐carboxylic acid ( 4 ), for labelling in carboxyl position with carbon‐11 (t1/2=20.4 min) to provide candidate PET radioligands for imaging brain cPLA2α. Compounds [11C] 1 – 4 were obtained for intravenous injection in adequate overall yields (1.1–5.5 %) from cyclotron‐produced [11C]carbon dioxide and with moderate molar activities (70–141 GBq μmol?1) through the use of Pd0‐mediated [11C]carbon monoxide insertion on iodo precursors. Measured logD7.4 values were within a narrow moderate range (1.9–2.4). After intravenous injection of [11C] 1 – 4 in mice, radioactivity uptakes in brain peaked at low values (≤0.8 SUV) and decreased by about 90 % over 15 min. Pretreatments of the mice with high doses of the corresponding non‐radioactive ligands did not alter brain time–activity curves. Brain uptakes of radioactivity after administration of [11C] 1 to wild‐type and P‐gp/BCRP dual knock‐out mice were similar (peak 0.4 vs. 0.5 SUV), indicating that [11C] 1 and others in this structural class, are not substrates for efflux transporters. 相似文献
70.
Cheryl L. Rock Shirley W. Flatt Hava-Shoshana Barkai Bilge Pakiz Dennis D. Heath 《Nutrition journal》2017,16(1):76