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101.
A rigorous quasi-experiment tested the ameliorative effects of a sabbatical leave, a special case of respite from routine work. We hypothesized that (a) respite increases resource level and well-being and (b) individual differences and respite features moderate respite effects. A sample of 129 faculty members on sabbatical and 129 matched controls completed measures of resource gain, resource loss, and well-being before, during, and after the sabbatical. Among the sabbatees, resource loss declined and resource gain and well-being rose during the sabbatical. The comparison group showed no change. Moderation analysis revealed that those who reported higher respite self-efficacy and greater control, were more detached, had a more positive sabbatical experience, and spent their sabbatical outside their home country enjoyed more enhanced well-being than others. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
102.
Ganoderma is normally dried to extend its shelf life without using chemical preservative and to concentrate the medicinal value in the fruiting body. Convective hot air drying characteristics of Ganoderma tsugae Murrill were evaluated in hot air circulated oven at different drying temperatures, sizes, and air flow rates. The drying kinetics of Ganoderma tsugae in kidney shape and slices were investigated and compared at different drying conditions. The variation of effective moisture diffusivity values at decreasing moisture contents during drying was determined from the drying data. Four well-known thin-layer drying models were fitted to the experimental data and the Midilli model was found to satisfactory describe the drying characteristics of kidney-shaped Ganoderma tsugae. Ganoderma tsugae dried at 50°C with air velocity of 1.401 ms?1 showed the highest retention of crude ganoderic acid content compared to other drying conditions.  相似文献   
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The ability of rats to return to the start location was examined with a 4-arm radial water maze. The task required rats to find 2 hidden platforms in sequence. Rats were released from 1 of 3 arms and there was a platform located in the fourth arm. Once a rat found this platform, a 2nd platform was raised in another location, which was either the start location, for 1 group, or another fixed location, for a control group. Across 3 experiments, all rats learned the location of the 1st fixed platform in 80 to 120 trials. However, rats had difficulty finding a 2nd platform if it was at the start location. Control groups revealed that rats could learn 2 platform locations and that the difficulty in learning to return to the start location did not seem to be attributable to its aversive nature. In separate groups, exposure to the start location was increased by starting the rats from an initially stable platform. Rats still did not readily learn to return to the start location. The authors suggest that start location, when varied, cannot readily be used to define the location of a hidden platform. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
105.
Maternal alcohol consumption during pregnancy places the fetus at risk for a number of neurological abnormalities and functional impairments. These deficits are 100% preventable by abstaining from alcohol use during pregnancy. Nevertheless, the worldwide prevalence of Fetal Alcohol Syndrome (FAS), the most severe outcome of prenatal alcohol consumption, is estimated at 0.97 cases per 1,000 live births (see May & Gossage, 2001). This paper examines awareness of the problem in Canada, the United States, the United Kingdom, and Australia along three dimensions: 1) the relationship between alcohol consumption rates and the incidence of FAS; 2) government action and policy creation; and 3) prevention/intervention initiatives and educational efforts. The extent of knowledge within each country affects, and is affected by, the level of research activity, the emphasis on policy creation, and the initiatives that drive educational efforts. At present, Canada and the U.S. have the highest levels of activity and a clear recognition of the problem. Activity in the U.K. and Australia is at the grass-roots level, although some promising movements toward greater public and professional awareness have begun. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
106.
Reliability of adult retrospective recall of lifetime tobacco use.   总被引:1,自引:0,他引:1  
Retrospective assessment of tobacco use underlies much of the data collected in epidemiological and genetic epidemiological research. Although individuals are asked to report lifetime tobacco use for periods spanning months to decades, the test-retest reliability intervals of the instruments often span only a few weeks to several months. The present analyses examined the test-retest reliability of retrospective tobacco use measures, including details of first use, circumstances of first use, and initial subjective reactions. The questions were part of the Lifetime Tobacco Use Questionnaire (LTUQ), a Web-based questionnaire designed to assess use of most forms of tobacco or nicotine retrospectively across the lifespan. A convenience sample of 236 men and women with history of tobacco use (Time 1 mean age, 44.9 years; 74.2% females; 75.1% regular monthly tobacco use) responded verifiably to invitations to self-administer the LTUQ two times, 2 years apart. Test-retest reliability analyses reflected high reliability for salient tobacco-use questions. Acceptable levels of reliability were observed for initial subjective reactions to smoking, if the scaled response options were dichotomized. Few differences in the reliability of recall were apparent between sexes and between age groups. These results indicate that recall of important tobacco use information can form a reliable basis for research.  相似文献   
107.
Variants of the TTLL5 gene, which encodes tubulin tyrosine ligase-like family member five, are a rare cause of cone dystrophy (COD) or cone-rod dystrophy (CORD). To date, only a few TTLL5 patients have been clinically and genetically described. In this study, we report five patients harbouring biallelic variants of TTLL5. Four adult patients presented either COD or CORD with onset in the late teenage years. The youngest patient had a phenotype of early onset severe retinal dystrophy (EOSRD). Genetic analysis was performed by targeted next generation sequencing of gene panels and assessment of copy number variants (CNV). We identified eight variants, of which six were novel, including two large multiexon deletions in patients with COD or CORD, while the EOSRD patient harboured the novel homozygous p.(Trp640*) variant and three distinct USH2A variants, which might explain the observed rod involvement. Our study highlights the role of TTLL5 in COD/CORD and the importance of large deletions. These findings suggest that COD or CORD patients lacking variants in known genes may harbour CNVs to be discovered in TTLL5, previously undetected by classical sequencing methods. In addition, variable phenotypes in TTLL5-associated patients might be due to the presence of additional gene defects.  相似文献   
108.
Fire Technology - Cooking equipment is involved in nearly half of home fires in the United States, with cooktop fires the leading cause of deaths and injuries in cooking-related fires. In this...  相似文献   
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110.
Pre-schooler's voices are absent in urban planning and design. With the possible exception of playgrounds, there is limited knowledge about their experiences in and expectations for urban environments. This paper discusses pre-schoolers' aspirations and desires for aesthetic and accessible green spaces as well as social and physical connectedness. Although this age range has so far been limited in its ability to inform policy and decision-makers, it is argued that pre-schoolers have the capacity and capability of making valuable contributions to design. In the eyes of pre-schoolers, creating a good city means to live in a safe place full of diverse destinations in which they can become streetwise and socialize as part of society.  相似文献   
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