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181.
BACKGROUND: Home parenteral nutrition (HPN) is used to treat intestinal failure. A minority of HPN patients are dependent on opiates and benzodiazepines to control pain and anxiety. The aim of this study was to determine what effects such drug dependence had on patient outcomes. METHODS: Ten dependent patients were prospectively compared with 10 well-matched, nondependent HPN patients for the same 12-month period. Episodes of line sepsis and other complications were documented and the cost of treatment estimated. Health status was measured using the SF36 and EuroQol instruments. RESULTS: The dependent group had significantly more episodes of central line sepsis (p = .0007) as well as other complications (p = .0002). This led to significantly longer periods of inpatient care (p = .0004) and therefore higher costs of treatment. Health status was lower in the dependent group; they reported more pain (p = .04) and less energy (p = .04). CONCLUSIONS: The complication rate and increased cost of treatment for opiate- and sedative-dependent patients receiving HPN significantly detract from the overall outcome of this therapy. 相似文献
182.
Valenzuela R.A. Landron O. Jacobs D.L. 《Vehicular Technology, IEEE Transactions on》1997,46(1):203-212
We explore techniques for the measurement of local mean signal strength at 900 MHz and 2 GHz. In particular, we characterize the impact of transmitter and receiver antenna rotation on the estimated local mean. Then, we explore the collection of high resolution data while moving along a linear trajectory and using linear averaging techniques to estimate the local mean. With this information, the best measurement techniques can be chosen depending on the required speed versus accuracy tradeoff. Finally, we use a ray tracing propagation model to evaluate different methods of calculating the local mean signal strength for indoor environments 相似文献
183.
184.
A transformational approach for proving termination of parallel logic programs such as GHC programs is proposed. A transformation
from GHC programs to term rewriting systems is developed; it exploits the fact that unifications in GHC-resolution correspond
to matchings. The termination of a GHC program for a class of queries is implied by the termination of the resulting rewrite
system. This approach facilitates the applicability of a wide range of termination techniques developed for rewrite systems
in proving termination of GHC programs. The method consists of three steps: (a) deriving moding information from a given GHC
program, (b) transforming the GHC program into a term rewriting system using the moding information, and finally (c) proving
termination of the resulting rewrite system. Using this method, the termination of many benchmark GHC programs such as quick-sort,
merge-sort, merge, split, fair-split and append, etc., can be proved.
This is a revised and extended version of Ref. 12). The work was partially supported by the NSF Indo-US grant INT-9416687
Kapur was partially supported by NSF Grant nos. CCR-8906678 and INT-9014074.
M. R. K. Krishna Rao, Ph.D.: He currently works as a senior research fellow at Griffith University, Brisbane, Australia. His current interests are in
the areas of logic programming, modular aspects and noncopying implementations of term rewriting, learning logic programs
from examples and conuterexamples and dynamics of mental states in rational agent architectures. He received his Ph.D in computer
science from Tata Institute of Fundamental Research (TIFR), Bombay in 1993 and worked at TIFR and Max Planck Institut für
Informatik, Saarbrücken until January 1997.
Deepak Kapur, Ph.D.: He currently works as a professor at the State University of New York at Albany. His research interests are in the areas
of automated reasoning, term rewriting, constraint solving, algebraic and geometric reasoning and its applications in computer
vision, symbolic computation, formal methods, specification and verification. He obtained his Ph.D. in Computer Science from
MIT in 1980. He worked at General Electric Corporate Research and Development until 1987. Prof. Kapur is the editor-in-chief
of the Journal of Automated Reasoning. He also serves on the editorial boards of Journal of Logic Programming, Journal on
Constraints, and Journal of Applicable Algebra in Engineering, Communication and Computer Science.
R. K. Shyamasundar, Ph.D.: He currently works as a professor at Tata Institute of Fundamental Research (TIFR), Bombay. His current intersts are in
the areas of logic programming, reactive and real time programming, constraint solving, formal methods, specification and
verification. He received his Ph.D in computer science from Indian Institute of Science, Bangalore in 1975 and has been a
faculty member at Tata Institute of Fundamental Research since then. He has been a visiting/regular faculty member at Technological
University of Eindhoven, University of Utrecht, IBM TJ Watson Research Centre, Pennsylvania State University, University of
Illinois at Urbana-Champaign, INRIA and ENSMP, France. He has served on (and chaired) Program Committees of many International
Conferences and has been on the Editorial Committees. 相似文献
185.
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187.
ME Sutherlin I Nishimori T Caffrey EP Bennett H Hassan U Mandel D Mack T Iwamura H Clausen MA Hollingsworth 《Canadian Metallurgical Quarterly》1997,57(21):4744-4748
The levels of mRNA expression of three UDP-N-acetyl-alpha-D-galactosamine:polypeptide GalNAc N-acetylgalactosaminyltransferases (GalNAc-transferases) were quantified for human adenocarcinoma cell lines from pancreas, colon, stomach, and breast. Two of the GalNAc-transferases, GalNAc-T1 and GalNAc-T2, were expressed constitutively and at low levels in most or all cell lines examined. A third GalNAc-transferase, GalNAc-T3, was differentially expressed. Well-differentiated adenocarcinoma cell lines expressed high levels and moderately differentiated cell lines expressed lower levels of GalNAc-T3. Cell lines classified as poorly differentiated failed to express GalNAc-T3 mRNA at levels that could be detected by Northern blot analysis. Differential expression of the GalNAc-T3 protein was confirmed in these cell lines by Western blotting. We propose that glycosylation in tumor cell lines may be regulated in part by differential expression of GalNAc-transferases, and we suggest that GalNAc-T3 gene expression may be a molecular indicator of differentiated adenocarcinoma. 相似文献
188.
189.
CL Mesh BL Cmolik DW Van Heekeren JH Lee D Whittlesey LM Graham AS Geha SJ Bowlin 《Canadian Metallurgical Quarterly》1997,11(6):612-619
A premise of cardiac risk stratification is that the added risk of coronary artery bypass grafting (CABG) is offset by the improved safety of subsequent vascular reconstruction (VR). We questioned if elective CABG is patients with severe peripheral vascular disease (PVD) is a relatively high-risk procedure. A cohort study of 680 elective CABG patients from January 1993 to December 1994 was performed using three mutually exclusive outcomes of complication-free survival, morbidity, and mortality. Patient characteristic, operative, and outcome data were prospectively collected. Retrospective review determined that 58 patients had either a standard indication for or a history of VR. Overall CABG mortality was 2.5%, with statistically similar but relatively higher rates for PVD as compared to non-PVD patients. In contrast, major morbidity occurred at rates 3.6-fold higher in PVD patients (39.7%) than in disease-free patients (16.7%) after adjustment for the effects of patient and operative variables (odds ratio [OR] 3.67, 95% confidence interval [CI] 1.93-6.99). CABG morbidity in the PVD patient was most likely in those patients with aortoiliac (OR 9.51, CI 3.20-28.27) and aortic aneurysmal (OR 5.24, CI 1.28-21.41) disease types. CABG in PVD patients is associated with significant major morbidity. Such morbidity may preclude or alter the timing of subsequent VR. 相似文献
190.
George V. Eleftheriades Gabriel M. Rebeiz 《Journal of Infrared, Millimeter and Terahertz Waves》1993,14(10):1925-1946
In this paper, an efficient implementation of the spectral domain moment technique is presented for computing the self and mutual coupling between slot antennas on a dielectric half-space. It is demonstrated that by the proper selection of the weighting functions in the method of moments, the analytic evaluation or simplification of the transverse moment integrals is enabled. This results into a significant reduction of the required computational labor. The method is then utilized in order to provide design data for the self and mutual admittances between two slot antennas on a dielectric substrate lens in the case of fused quartz (∈ r =3.80), crystal quartz (∈ r =4.53), silicon (∈ r =11.9) and GaAs (∈ r =12.8). The presented technique and associated results are useful when designing twin slot quasi-optical receivers, imaging arrays, phased arrays or power-combining arrays of slot elements at millimeter-wave frequencies. 相似文献