Systemic lupus erythematosus with a protein-losing enteropathy

Anasarca with pronounced hypoalbuminemia developed in a young woman 15 months after the onset of a mild, arthralgic type of systemic lupus erythematosus (SLE) without evidence of active nephritis. Investigation indicated a gastrointestinal rather than a renal site for protein loss. A full clinical remission was achieved with low-dose corticosteroid therapy.     

Acute pretreatment with pyrazole and ethanol: effects on glucose-induced changes in insulin and glucagon

Ethanol suppressed, in a dose-related manner, glucose-induced insulin (IRI) release and thus delayed the disappearance of glucose from the blood of rats. Pretreatment with pyrazole, an alcohol dehydrogenase inhibitor, exacerbated the effect of ethanol on IRI release, glucose tolerance and glucagon (IRG) release. These results suggest that ethanol produces glucose intolerance by inhibiting glucose-induced IRI release and by augmenting IRG release. Moreover, these findings indicate that ethanol does not have to be metabolized completely in order to produce these effects.     

Silicate-Containing Sodium Beta-Alumina Solid Electrolytes

Sodium beta-alumina solid electrolytes were prepared containing up to 7.5 wt% SiO₂ and their density, soda content, micro-structure, and ionic resistivity were studied. The resulting microstructures have glassy sodium ahminosilicate phases inhomogeneously distributed. The glassy phase collects preferentially at triple grain junctions, but occasionally penetrates along some grain boundaries as a thin layer (10 to 20 Å). Alpha-alumina is also present, especially with high silica content and when the samples are not protected with β-alumina powder during sintering. The total specific ionic resistivity follows a dependence on silicate content typical of 2-phase mixtures.