Effects of temperature on a.c. magnetostriction in grain-oriented silicon-iron

The a.c. magnetostriction of conventional grain-oriented 3 1/4% silicon-iron and more highly oriented silicon-iron has been measured from room temperature up to the Curie point using high temperature strain gauges. Curves of magnetostriction plotted against flux density showed that a definite change in the magnetization process occurred at about 300° C extending to 400° C for both types of material. This was considered to be due to the onset of magnetic annealing, considerably modified by the effect of the coating on the materials. From the experimental results the magnetostriction constant ₁₀₀ has been calculated using a predicted domain structure and was found to agree well with single crystal values apart from within the 300 to 400° C region.     

Macsyma: A personal history

The Macsyma system arose out of research on mathematical software in the AI group at MIT in the 1960s. Algorithm development in symbolic integration and simplification arose out of the interest of people, such as the author, who were also mathematics students. The later development of algorithms for the GCD of sparse polynomials, for example, arose out of the needs of our user community. During various times in the 1970s the computer on which Macsyma ran was one of the most popular nodes on the ARPANET. We discuss the attempts in the late 70s and the 80s to develop Macsyma systems that ran on popular computer architectures. Finally, we discuss the impact of the fundamental ideas in Macsyma on the author’s current research on large scale engineering and socio-technical systems.     

Cortisol in physiological concentrations acts within minutes to modify effects of prolactin and growth hormone on prostaglandin secretion: importance of effect in modulating cellular responses to calcium and cyclic nucleotides

We propose that intracellular prostaglandins (PGs) are essential for the final expression of the effects of second messengers in most cells. We suggest that the amounts of PGs required are very small (in the picomolar range) and are much lower than those used in most current PG studies. We suggest that while therapeutic levels of inhibitors of PG synthetase may be adequate to block the overflow of PGs from cells, they are in most cases unlikely to reduce intracellular PGs sufficiently to test the role of such PGs. We propose that there is a basal level of PG synthesis unaffected by hormones but that above this level PG synthesis is regulated by the interplay between physiological levels of cortisol, prolactin, growth hormone and thyroid hormones. For the most part prolactin seems to stimulate PG synthesis and cortisol to inhibit it: cortisol has, however, no inhibitory effect on basal PG synthesis. In reducing prolactin-stimulated PG synthesis cortisol is 1000-2000 times more potent than indomethacin on a molar basis. We suggest that the regulation of intracellular PG levels is the mechanism of the so-called "permissive" actions of these hormones. These concepts could prove important in the understanding of many aspects of physiology and pathophysiology including diurnal and seasonal changes in hormone responsiveness. They are also relevant to the use of established drugs and the design of new ones.     

Leukemic reticuloendotheliosis: a medical technologist's diagnosis

Leukemic reticuloendotheliosis (LRE) or "hairy cell leukemia" is a unique form of leukemia which possesses features of both a chronic and acute leukemia. Its characteristic morphology, clinical diagnosis, and treatment are discussed. A high index of suspicion should make this entity easily diagnosed by the medical technologist.     

Reasoning about Knowledge: A Response by the Authors

Minds and Machines -     

Generalization to Novel Views: Universal,Class-based,and Model-based Processing

A major problem in object recognition is that a novel image of a given object can be different from all previously seen images. Images can vary considerably due to changes in viewing conditions such as viewing position and illumination. In this paper we distinguish between three types of recognition schemes by the level at which generalization to novel images takes place: universal, class, and model-based. The first is applicable equally to all objects, the second to a class of objects, and the third uses known properties of individual objects. We derive theoretical limitations on each of the three generalization levels. For the universal level, previous results have shown that no invariance can be obtained. Here we show that this limitation holds even when the assumptions made on the objects and the recognition functions are relaxed. We also extend the results to changes of illumination direction. For the class level, previous studies presented specific examples of classes of objects for which functions invariant to viewpoint exist. Here, we distinguish between classes that admit such invariance and classes that do not. We demonstrate that there is a tradeoff between the set of objects that can be discriminated by a given recognition function and the set of images from which the recognition function can recognize these objects. Furthermore, we demonstrate that although functions that are invariant to illumination direction do not exist at the universal level, when the objects are restricted to belong to a given class, an invariant function to illumination direction can be defined. A general conclusion of this study is that class-based processing, that has not been used extensively in the past, is often advantageous for dealing with variations due to viewpoint and illuminant changes.     

The effect of cognitive and affective aspects on usability

Studies on customer’s needs, desires and preferences have become highly important in the product design and development process. One consideration in usability is the cognitive aspect, which is related to the accommodation and evaluation of human cognitive capabilities, limitations and tendencies. In addition to the cognitive aspect, a recent study has shown that the affective aspect has been considered in the evaluation of product usability. Thus, both cognitive and affective aspects are deemed to be important for product design and the development process. Inherently, both aspects deliver complete human and product interaction and experience. However, studies that consider the affective process as a complement to the cognitive process for usability are relatively rare. To address this gap, this study discusses how an integrative framework of the cognitive and affective aspects can be applied to a product for usability assessment via empirical studies on e-commerce and e-learning platforms. The sample involved 230 respondents, using purposive sampling. The result shows that both cognitive and affective aspects have a significant effect, although with different weights. The affective aspect has been shown to improve product usability and user’s acceptance.     

Influence of substrate temperature on crystalline copper aluminium oxide thin films synthesized through chemical spray pyrolysis (CSP) technique

Copper aluminium oxide (CuAlO₂) of well ordered crystalline films were deposited on to glass substrates with Cu/Al ratio r = 0.8 at the substrate temperatures of 250, 300, 350, 400 and 450 °C. Films which were characterized had a thickness of the order of few micrometers. Films deposited at the optimized deposition temperature (450 °C) revealed well-crystalline CuAlO₂ phase with XRD peak at 2θ = 31.7° corresponds to (006) reflection. The peak positions of the core level XPS spectra, confirm the presence of delafossite CuAlO₂ phase. The optical transmission of 80 % has been observed in the visible spectrum. The obtained band gap energy is 4.1 eV. From the observed results it was evidenced that the substrate temperature has strong influence on the structural and optical properties of the spray pyrolysed copper aluminium oxide films.