全文获取类型
收费全文 | 552篇 |
免费 | 3篇 |
国内免费 | 2篇 |
专业分类
电工技术 | 4篇 |
综合类 | 6篇 |
化学工业 | 30篇 |
金属工艺 | 29篇 |
机械仪表 | 16篇 |
建筑科学 | 4篇 |
能源动力 | 4篇 |
轻工业 | 21篇 |
水利工程 | 1篇 |
石油天然气 | 4篇 |
无线电 | 9篇 |
一般工业技术 | 76篇 |
冶金工业 | 322篇 |
原子能技术 | 24篇 |
自动化技术 | 7篇 |
出版年
2021年 | 3篇 |
2020年 | 3篇 |
2019年 | 3篇 |
2018年 | 4篇 |
2017年 | 4篇 |
2016年 | 7篇 |
2014年 | 6篇 |
2013年 | 24篇 |
2012年 | 8篇 |
2011年 | 7篇 |
2010年 | 11篇 |
2009年 | 13篇 |
2008年 | 8篇 |
2007年 | 4篇 |
2006年 | 5篇 |
2005年 | 4篇 |
2004年 | 6篇 |
2003年 | 12篇 |
2002年 | 7篇 |
2001年 | 3篇 |
2000年 | 3篇 |
1999年 | 9篇 |
1998年 | 111篇 |
1997年 | 53篇 |
1996年 | 26篇 |
1995年 | 20篇 |
1994年 | 17篇 |
1993年 | 26篇 |
1992年 | 6篇 |
1991年 | 7篇 |
1990年 | 9篇 |
1989年 | 14篇 |
1988年 | 5篇 |
1987年 | 8篇 |
1986年 | 5篇 |
1985年 | 5篇 |
1983年 | 5篇 |
1982年 | 4篇 |
1981年 | 4篇 |
1979年 | 4篇 |
1977年 | 15篇 |
1976年 | 23篇 |
1975年 | 4篇 |
1974年 | 2篇 |
1973年 | 5篇 |
1972年 | 3篇 |
1971年 | 4篇 |
1970年 | 2篇 |
1969年 | 3篇 |
1966年 | 3篇 |
排序方式: 共有557条查询结果,搜索用时 15 毫秒
11.
Magossi Maiara S. Maraldi Vitor A. Magossi Mariana S. DA Costa Fabíola M. Alves Kamilla Franco Fernanda D. S. DO Carmo Devaney R. 《SILICON》2021,13(7):2243-2255
Silicon - This study describes the preparation and characterization of 3-chloropropyl silica gel with 4-amino-5-(4pyridyl)-4H-1,2,4-triazole-3-thiol (SGA) for copper adsorption in different media.... 相似文献
12.
Andreas Brodehl Alexey Meshkov Roman Myasnikov Anna Kiseleva Olga Kulikova Brbel Klauke Evgeniia Sotnikova Caroline Stanasiuk Mikhail Divashuk Greta Marie Pohl Maria Kudryavtseva Karin Klingel Brenda Gerull Anastasia Zharikova Jan Gummert Sergey Koretskiy Stephan Schubert Elena Mershina Anna Grtner Polina Pilus Kai Thorsten Laser Valentin Sinitsyn Sergey Boytsov Oxana Drapkina Hendrik Milting 《International journal of molecular sciences》2021,22(7)
About 50% of patients with arrhythmogenic cardiomyopathy (ACM) carry a pathogenic or likely pathogenic mutation in the desmosomal genes. However, there is a significant number of patients without positive familial anamnesis. Therefore, the molecular reasons for ACM in these patients are frequently unknown and a genetic contribution might be underestimated. Here, we used a next-generation sequencing (NGS) approach and in addition single nucleotide polymor-phism (SNP) arrays for the genetic analysis of two independent index patients without familial medical history. Of note, this genetic strategy revealed a homozygous splice site mutation (DSG2–c.378+1G>T) in the first patient and a nonsense mutation (DSG2–p.L772X) in combination with a large deletion in DSG2 in the second one. In conclusion, a recessive inheritance pattern is likely for both cases, which might contribute to the hidden medical history in both families. This is the first report about these novel loss-of-function mutations in DSG2 that have not been previously identi-fied. Therefore, we suggest performing deep genetic analyses using NGS in combination with SNP arrays also for ACM index patients without obvious familial medical history. In the future, this finding might has relevance for the genetic counseling of similar cases. 相似文献
13.
14.
JD Reveille GS Alarcón SE Fowler SR Pillemer R Neuner DO Clegg IS Mikhail DE Trentham JC Leisen G Bluhm SM Cooper H Duncan M Tuttleman SP Heyse JT Sharp B Tilley 《Canadian Metallurgical Quarterly》1996,39(11):1802-1807
OBJECTIVE: To examine the effect of alleles encoding the "shared"/"rheumatoid" epitope on rheumatoid arthritis (RA) disease severity in patients who participated in the minocycline in RA (MIRA) trial. METHODS: Of 205 patients with a week-48 visit, blood was available for typing of HLA-DRB1 and HLA-DQB1 in 174 (85%) and successfully completed in 169 (82%). Baseline erosions were used to assess disease severity and new erosions at the last visit served as a proxy for progression. RESULTS: At baseline, there was no association between the presence of erosive disease or rheumatoid factor status and the dose of rheumatoid epitope (homozygous, heterozygous, none) or the specific alleles identified. At the final visit, a gradient was observed for the 3 allelic subgroups (and their gene doses) in the occurrence of new erosions among the Caucasian placebo-treated, but not the minocycline-treated, patients. A treatment group/HLA-DR4 epitope interaction was demonstrated in multivariate analyses. Approximately two-thirds of African-American patients did not have the rheumatoid epitope. CONCLUSION: HLA-DRB1 oligotyping may be useful in predicting the progression of disease in some Caucasian patients. Our study corroborates the infrequency of the epitope among African-American patients with RA. 相似文献
15.
A recent intracellular study of dorsal cochlear nucleus (DCN) neurons in vitro by Manis [P. B. Manis, J. Neurosci. 10, 2338-2351 (1990)] suggests that the expression of the pause-build discharge pattern is in large part dependent on hyperpolarization of their membrane potentials in a period just preceding a depolarizing stimulus ("hyperpolarization conditioning" hypothesis). Our examination of the activity of a sample of pause-build units (n = 72) revealed suppression of discharge activity during a time window of the silent interstimulus interval (SII) just preceding the tone burst relative to the spontaneous rate in 74% of all units. The discharge suppression of a subset of DCN pause-build units in the SII satisfies a requirement of the "hyperpolarization conditioning" hypothesis, and thus supports the hypothesis. 相似文献
16.
17.
18.
19.
20.
IK Temple RJ Gardner DO Robinson MS Kibirige AW Ferguson JD Baum JC Barber RS James JP Shield 《Canadian Metallurgical Quarterly》1996,5(8):1117-1121
Transient neonatal diabetes mellitus (TNDM) is a rare form of childhood diabetes which usually resolves in the first 6 months of life but which predisposes to type 2 diabetes of adult onset. We recently reported paternal uniparental isodisomy of chromosome 6 (UPD6) in two children with TNDM and proposed that there may be an imprinted gene important in the aetiology of diabetes on chromosome 6. We now describe two unrelated families which independently suggest that the gene is imprinted, is paternally expressed and maps to 6q22-q23. One family has a duplication while the other, with familial TNDM, shows linkage to a marker in this region. 相似文献