An improved algorithm for layout design in cellular manufacturing systems

Layout has a significant role on the efficiency of manufacturing systems, but it has not received attention of researchers in comparison to cell formation in cellular manufacturing systems. In this paper, a mathematical model for facility layout in a cellular manufacturing system is proposed that minimizes both inter-cell and intra-cell material handling costs. A variant of simulated annealing algorithm is developed to solve the model. The developed algorithm produces solutions with better quality and less computation time in comparison with the benchmarked algorithm. The superiority of the algorithm in computation time is considerable especially when the size of the problem increases.     

A new QoS-aware TDMA/FDD MAC protocol with multi-beam directional antennas

With the ever-increasing demand for wireless real-time services and continuing emergence of new multimedia applications especially for mobile users, it is necessary for the network to support various levels of quality of service (QoS) while maximizing the utilization of scarce and expensive wireless channel resources. Considering this fact, a new TDMA/FDD MAC protocol integrating a novel QoS management algorithm and multi-beam Directional Antennas (DAs) to efficiently exploit wireless resources has been developed and presented in this paper. It supports all ATM CBR, VBR, ABR and UBR service classes by adopting a well-managed dynamic guarantee-based QoS scheduling algorithm. The work mainly aims at increasing the wireless system throughput as well as improving the call-blocking ratios and end-to-end delays for real-time applications. This seamless communication enables both handling real-time multimedia traffics in a fair manner and granting call requests on the basis of the connection types. The system has been developed, modeled and simulated using OPNET Modeler. The simulation results show that the QoS-aware TDMA/FDD MAC with multi-beam DAs has substantially increased the system throughput and that the call-blocking ratio has been reduced from 86% to 18%, when the proposed MAC with 8-Beam antennas is employed instead of the regular MAC.     

Higher order dispersive and dissipative hybrid method for the numerical solution of oscillatory problems

In this paper, an improved explicit two-step hybrid method with fifth algebraic order is derived. The new method possesses dispersion of order 10 and dissipation of order seven, which is first of its kind in the literature. Numerical experiment reveals the superiority of the new method for solving oscillatory or periodic problems over several methods of the same algebraic order.     

The ultrastructural characteristics of the changes in the rat liver in the dynamics of experimental endotoxemia

Electron microscopic study was performed in the experiments on the rat liver while intravenously administering E. coli endotoxin. The dynamics of ultrastructural disorders during endotoxemia has been established and the role of "Kupffer cell-hepatocyte" microsystem in the liver detoxification function is shown.     

Potential difference across subcellular particle membranes. II. Compensation method of measurement

"Zero-loop" of the molecular potential transformer of submitochondrial particles (SMP) is separated from the remaining electron transfer chain by rotenone, and its e.m.f. ET=0,003+RT/2F in [NADP X H] [NAD+]/[NADP+] [NAD X H] volts is used in the compensative method of measurement of the potential difference across the SMP membrane (delta USMP). The phospholipid membrane, measuring the concentration of the penetrating anions in the solution contained SMP, is used as "zero-indicators". This concentration drops monotonically with increase in delta USMP. Delta USMP is equal to ET when the addition of substrates of transhydrogenase reaction with definite ET does not change the potential across phospholipid membrane.     

The clinical significance of granulocyte colonies in bone marrow cultures

The culture system for in vitro evaluation of "colony forming units - culture (CFU-c)" is briefly outlined. This method offers a new approach to studies of proliferation and differentiation of hemopoietic progenitor cells, especially in disorders of granulopoiesis. From available published data it is evident that quantitation of CFU-c is also an indicator of diagnostic and prognostic value for assessment of various types of leukemia. The CFU-c assay has furthermore been introduced to test the viability and proliferating capacity of cryopreserved bone marrow, especially with a view to possible transfusion of stored autologous bone marrow as an adjuvant to cytostatic therapy.     

From Reparative Surgery to Regenerative Surgery: State of the Art of Porous Hydroxyapatite in Cranioplasty

Decompressive craniectomy is one of the most common neurosurgical procedures, usually performed after neuropathological disorders, such as traumatic brain injury (TBI), but also vascular accidents (strokes), erosive tumours, infections and other congenital abnormalities. This procedure is usually followed by the reconstruction of the cranial vault, which is also known as cranioplasty (CP). The gold-standard material for the reconstruction process is the autologous bone of the patient. However, this is not always a feasible option for all patients. Several heterologous materials have been created in the last decades to overcome such limitation. One of the most prominent materials that started to be used in CP is porous hydroxyapatite. PHA is a bioceramic material from the calcium phosphate family. It is already widely used in other medical specialties and only recently in neurosurgery. In this narrative review of the literature, we summarize the evidence on the use of PHA for cranial reconstruction, highlighting the clinical properties and limitations. We also explain how this material contributed to changing the concept of cranial reconstruction from reparative to regenerative surgery.     

Design of dual‐band microstrip patch antenna with right‐angle triangular aperture slot for energy transfer application

This work focusing on the dual‐band antenna design with rectifying circuit for energy transfer system technology for enhancement gain performance. The air gap technique is applied on this microstrip antenna design work to enhance the antenna gain. The work begins with designing and analyzing the antenna via the CST Microwave Studio software. After validation on acceptable performance in simulation side is obtained, the return loss, S₁₁ of the antenna is measured using vector network analyzer equipment. The rectifier circuit is used to convert the captured signal to DC voltage. This projected dual‐band antenna has successfully accomplished the target on return loss of ?44.707 dB and ?32.163 dB at dual resonant frequencies for 1.8 GHz and 2.4 GHz, respectively. This proposed antenna design benefits in low cost fabrication and has achieved high gain of 6.31 dBi and 7.82 dBi for dual‐band functioning frequencies.     

Integrated high-quality rectifier-regulators

A new family of AC-DC converters is derived which integrate the functions of low-harmonic rectification, low-frequency energy storage, and wide-bandwidth output voltage control into a single converter containing one, two, or four active switches. These converters utilize a discontinuous conduction mode input inductor, an internal energy storage capacitor, and transformer secondary circuits which resemble the bridge, forward, flyback, or Cuk DC-DC converters. A large-signal equivalent circuit model for this family is presented, which uses the “loss-free resistor” concept. Design strategies and experimental results are given. High-performance regulation with satisfactory line-current harmonics is demonstrated with conventional duty-ratio control. Further improvements in line current are possible by simultaneous duty-ratio and switching-frequency control