Platelet aggregation in partially obstructed vessels and its elimination with aspirin

There is a considerable controversy regarding the frequency and significance of vascular lesions in leprosy. Twenty-six cases of leprosy below the age of 40 years, without any local or systemic arterial disease and normal looking hands were subjected to brachial arteriography. One patient had posterior tibial arteriography also. The diagnosis of leprosy was confirmed by histology or bacteriological staining techniques. Biopsy material was studied from the involved areas and similar material was obtained from nine matched control subjects at autopsy. Skin thermometry and reflex vasodilatation was studied in eight cases. Arteriographic abnormalities such as occlusion, narrowing, tortuosity, dilatation, irregularity and incomplete filling were seen in more than two vessels in the hand in 50%, and in the digits in 75% of the cases. The ulnar artery was more frequently involved than the radial. Superficial and deep palmar arches were equally affected. Marked increase in arcuate vessels was noticed in nearly three-quarters of the patients, and in some, arcuate vessles were serving as collaterals. Histologically all sizes of vessles, including the capillaries, showed changes in nearly half the cases. Reflex vasodilation was lost in three cases of dimorphous leprosy and impaired or absent in three out of five cases of lepromatous leprosy. There was no predilection for any form of leprosy to show arterial changes more than the other. This study clearly demonstrates that the arterial involvement in leprosy is very frequent and must be playing an important role in causing mutilation and deformities of hands and feet.     

Effect of long-term annealing upon antiflake treatment on the structure and impact toughness of the 40KhGM steel

The long-term annealing used for the removal of hydrogen from forgings affects the structure, impact toughness, and the fracture mode of the steel. It stimulates the fragmentation and spheroidization of cementite plates and the polygonization of ferrite. The impact toughness increases by a factor of 2–10, depending on the sulfur content. The structure changes occurring upon annealing increase the resistance of the metal to flake growth.     

Flux-gate magnetic field sensor based on yttrium iron garnet films for magnetocardiography investigations

Technical Physics Letters - A new type of f lux-gate vector magnetometer based on epitaxial yttrium iron garnet films has been developed and constructed for magnetocardiography (MCG)...