Combining hygrothermal and corrosion models to predict corrosion of metal fasteners embedded in wood

A combined heat, moisture, and corrosion model is presented and used to simulate the corrosion of metal fasteners embedded in solid wood exposed to the exterior environment. First, the moisture content and temperature at the wood/fastener interface is determined at each time step. Then, the amount of corrosion is determined spatially using an empirical corrosion rate model and the inputs of the first step. The result is a corrosion profile along the length of the fastener generated by summing the corrosion depths determined at each time step. We apply the combined model to predict the annual corrosion depth along a metal fastener in wood decks situated in nine different US cities. Corrosion profiles are found to exhibit the same general shape independently of climatic load, with the largest amount of corrosion occurring at 1–5 mm from the wood surface with corrosion depths ranging from 5 μm in Phoenix, Arizona to 45 μm in Hilo, Hawaii. Corrosion is confined to the first 7–20 mm of the fastener below the wood surface. By varying the climatic loads, we find that although there is a definite relation between total annual rain and total annual corrosion, under the same rain loads corrosion is higher for a climate with more evenly distributed rain events. The proposed combined model is able to capture corrosion behavior under varying loading. A sensitivity analysis gives guidelines for future corrosion modeling work for fasteners in wood.     

Coherence measures and their relation to fuzzy similarity and inconsistency in knowledge bases

Intuitively it seems that the coherence of information received from heterogeneous sources should be one factor in determining the reliability or truthfulness of the information, yet the concept of coherence is extremely difficult to define. This paper draws on recent work on probabilistic measures of coherence by investigating two measures with contrasting properties and then explores how this work relates to similarity of fuzzy sets and comparison of knowledge bases in cases where inconsistency is present. In each area contrasting measures are proposed analogous to the probabilistic case. In particular, concepts of fuzzy and logical independence are proposed and in each area it is found that sensitivity to the relevant concept of independence is a distinguishing feature between the contrasting measures. In the case of inconsistent knowledge bases, it is argued that it is important to take agreeing information and not just conflicting and total information into account when comparing two knowledge bases. One of the measures proposed achieves this and is shown to have a number of properties which enable it to overcome some problems encountered by other approaches.     

Memory liabilities associated with hypnosis: does low hypnotizability confer immunity?

Retrospective analyses of data from the authors' program of research on hypnosis and memory are presented, with special emphasis on effects observed among low hypnotizable individuals. In Experiment 1, participants completed seven forced-recall trials in an attempt to remember a series of pictures that had been shown 1 week earlier. For half the participants, the middle five trials were carried out using hypnotic procedures; the remaining participants performed all recall attempts in a motivated waking condition. Hypnosis failed to enhance correct recall for either high or low hypnotizable participants beyond the hypermnesia and reminiscence effects associated with repeated retrieval attempts over time. However, whereas high hypnotizable participants produced substantial numbers of confident recall errors (i.e., intrusions) independent of the use of hypnosis, low hypnotizable participants exposed to hypnotic procedures reported significantly more intrusions than their counterparts in the waking condition. In Experiment 2, participants were asked to identify whether specific recollections, reported during two forced-interrogatory recall tests conducted 1 week earlier, had originated in the first or second of those tests. A general bias to misattribute previously reported recollections to the first of two recall occasions was observed; however, the effect was greatest among low hypnotizables who had undergone the second recall attempt in hypnosis. The findings imply that highly hypnotizable individuals are not unique in their vulnerability to distortions of memory induced by hypnotic techniques. Individuals of lesser hypnotic capacity also manifest memory alterations when exposed to such procedures.     

Decentralized adaptive control of electrically-driven manipulators

This paper presents two new decentralized strategies for motion control of uncertain electrically-driven manipulators. The first controller is an adaptive position regulation scheme which ensures semiglobal asymptotic convergence of the position error if no external disturbances are present and semiglobal convergence of the error to an arbitrarily small neighborhood of zero in the presence of bounded disturbances. It is shown that the regulation scheme can be modified to provide accurate trajectory tracking control through the introduction of adaptive feedforward elements in the control law; this second control strategy retains the simple decentralized structure of the first controller and ensures arbitrarily accurate tracking in the presence of bounded disturbances. Each of the adaptive schemes is very efficient computationally and requires virtually no information concerning either the manipulator or actuator models. The results of computer simulations and laboratory experiments with both terrestrial and space manipulators demonstrate that accurate and robust motion control can be achieved by using the proposed approach.     

Bupropion and desipramine increase dopamine transporter mRNA expression in the ventral tegmental area/substantia nigra of rat brain

The homeobox gene Otx2 is a mouse cognate of the Drosophila orthodenticle gene, which is required for development of the brain, rostral to rhombomere three. We have investigated the mechanisms involved in this neural function and specifically the requirement for Otx2 in the visceral endoderm and the neuroectoderm using chimeric analysis in mice and explant recombination assay. Analyses of chimeric embryos composed of more than 90% of Otx2-/- ES cells identified an essential function for Otx2 in the visceral endoderm for induction of the forebrain and midbrain. The chimeric studies also demonstrated that an anterior neural plate can form without expressing Otx2. However, in the absence of Otx2, expression of important regulatory genes, such as Hesx1/Rpx, Six3, Pax2, Wnt1 and En, fail to be initiated or maintained in the neural plate. Using explant-recombination assay, we could further demonstrate that Otx2 is required in the neuroectodem for expression of En. Altogether, these results demonstrate that Otx2 is first required in the visceral endoderm for the induction, and subsequently in the neuroectoderm for the specification of forebrain and midbrain territories.     

Ergonomic working conditions for the nursing team in a cardiology unit]

Aiming at finding out the ergonomics conditions of the nursing personnel in a hospital admission unit, the authors utilized as a methodological presupposition the search for a global experienced work situation through the analysis of some elements as: the man (nursing worker); the work activity (prescribed duty, real activities and work position) and the environment (temperature, noise and illumination). The authors selected the Cardiology admission unit for the site of their research. The results verified that the nursing workers the mentioned unit face problems related to salaries, work installations, relationship, work organization, levels of formation and the activities executed. The authors suggested some recommendations.     

Morbillivirus infections in wildlife (in relation to their population biology and disease control in domestic animals)

The three members of the morbillivirus genus that infect wildlife in ecosystems where domestic animals occur are rinderpest, peste des petits ruminants (PPR) and canine distemper. Data on the relative susceptibility of species of the Order Artiodactyla for rinderpest have been obtained from historical records of outbreaks. Rinderpest in wildlife has only occurred in equatorial and eastern Africa since the great pandemic of 1889-1897. The distributions, densities and population dynamics of susceptible species in this region are described. There has only been one recorded outbreak of PPR in wildlife but the possibility of its occurrence in the future now that it is present in many parts of west and eastern Africa is discussed. Wild carnivora are not likely to be important maintenance hosts for canine distemper but the disease is of significance in free-ranging carnivores and particularly in small populations of endangered susceptible wildlife species. It is also of great significance in zoo populations.     

Selection and characterization of Toxoplasma gondii mutants resistant to artemisinin

Toxoplasma gondii infection, like malaria, is sensitive to inhibition by artemisinin (ART). Mechanisms of action for ART in malaria treatment have been proposed, but little is known about its effects in T. gondii infection. To better understand its inhibitory effects on T. gondii, mutants resistant to ART were selected by progressive culture in permissive levels of the drug. Five clonal isolates were established and characterized. The isolates were approximately 65-fold less sensitive to ART than is the parental RH and showed cross-resistance to the ART derivatives dihydroartemisinin and artemether. In addition to ART resistance, 1 clone (C9) formed morphologically unusual parasitophorous vacuoles and another (A2) was avirulent for mice and protected mice from challenge with the wild type. These clonal T. gondii mutant isolates will be useful for the study of not only the mechanism of action of ART but also parasite vacuole biology and virulence factors.     

SYSTEMS DEVELOPMENT THE DATE WARS Learning Management by Issue

It is the year 2020. The effects of the Date Wars at the turn of the century— in fact, the turn of the millennium— have been mostly absorbed. Has the IS community learned from the past?