基于Matlab变压器故障红外图像边缘检测研究

红外图像处理在电力设备故障检测方面有着广泛的应用。介绍几种边缘检测方法,通过MATLAB对各种算法进行变压器故障红外诊断图像处理,实现边缘检测,比较这些方法的优越性,根据实际需要选取相应的边缘算法。     

A novel crystallization method for visualizing the membrane localization of potassium channels

The high permeability of K+ channels to monovalent thallium (Tl+) ions and the low solubility of thallium bromide salt were used to develop a simple yet very sensitive approach to the study of membrane localization of potassium channels. K+ channels (Kir1.1, Kir2.1, Kir2.3, Kv2.1), were expressed in Xenopus oocytes and loaded with Br ions by microinjection. Oocytes were then exposed to extracellular thallium. Under conditions favoring influx of Tl+ ions (negative membrane potential under voltage clamp, or high concentration of extracellular Tl+), crystals of TlBr, visible under low-power microscopy, formed under the membrane in places of high density of K+ channels. Crystals were not formed in uninjected oocytes, but were formed in oocytes expressing as little as 5 microS K+ conductance. The number of observed crystals was much lower than the estimated number of functional channels. Based on the pattern of crystal formation, K+ channels appear to be expressed mostly around the point of cRNA injection when injected either into the animal or vegetal hemisphere. In addition to this pseudopolarized distribution of K+ channels due to localized microinjection of cRNA, a naturally polarized (animal/vegetal side) distribution of K+ channels was also frequently observed when K+ channel cRNA was injected at the equator. A second novel "agarose-hemiclamp" technique was developed to permit direct measurements of K+ currents from different hemispheres of oocytes under two-microelectrode voltage clamp. This technique, together with direct patch-clamping of patches of membrane in regions of high crystal density, confirmed that the localization of TlBr crystals corresponded to the localization of functional K+ channels and suggested a clustered organization of functional channels. With appropriate permeant ion/counterion pairs, this approach may be applicable to the visualization of the membrane distribution of any functional ion channel.     

不同掺砾量对黏土心墙的影响

为考察西南地区某黏土心墙坝在不同心墙掺砾水平下心墙的工作性态与安全情况,进而确定心墙坝掺砾施工方案,采用三维有限元方法,在不同的掺砾量水平之下,充分考虑掺砾量的增加对心墙渗透性与变形强度的影响,采用双线法计算各掺砾方案下的湿化变形,研究了大坝完建期及蓄水运行时心墙水平与竖向位移的变化规律,同时采用拱效应系数分析心墙拱效应的变化情况。研究结果表明:当掺砾量控制在50%以下时,伴随掺砾量增加,心墙的沉降变形减少,顺河流向变形减少,使心墙拱效应得到改善;当掺砾量大于50%时,掺砾对心墙的沉降变形与拱效应的抑制作用减弱,同时心墙顺河流向变形量增加。鉴于对于黏土心墙工作性态的综合考虑,建议相应工程中心墙料掺砾量宜小于50%。     

纤维增强富浆胶凝砂砾石的性能研究

本文首次研究了纤维对富浆胶凝砂砾石性能的作用,分析了6种不同纤维对富浆胶凝砂砾石坍落度、抗压强度、劈裂抗拉强度、抗冻性的影响,讨论了振捣时间对富浆胶凝砂砾石抗冻性的影响,并结合实际工程,给出了富浆胶凝砂砾石推荐配合比。结果表明,随着单丝聚丙烯纤维掺量的增加,富浆胶凝砂砾石的坍落度逐渐减小,抗压强度和劈裂抗拉强度先增大后减小;聚丙烯纤维和钢纤维对富浆胶凝砂砾石的增强效果最好,且掺入1. 2 kg/m~3聚丙烯纤维、钢纤维的富浆胶凝砂砾石抗冻性分别可达400次、300次;为保障纤维提高富浆胶凝砂砾石抗冻性的效果,掺入纤维的富浆胶凝砂砾石振捣时间不宜长于45 s;给出了岷江航电犍为防护堤垫层及防渗保护层富浆胶凝砂砾石的推荐配合比,掺入聚丙烯纤维后,可减小水泥用量。     

基于μTAS 系统多参量血液分析生物传感器与测量仪器的研究

研制出一种基于μTAS 系统的血液分析型医用多参量测量的生物传感测量仪器.该传感器采用 IDA 结构的微电极阵列,分别固定上不同的酶,当工作区中的微电极上滴上少许血样,通过检测微电极上生化反应所产生的微电流,可同时测试出血液中血糖、胆固醇、酮体和乳酸的浓度.测量仪器的电流测量范围 0-40 μA,灵敏度为 1 nA.该系统经北京医疗器械研究所测试,取得较好的实验结果.     

Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer

STUDY OBJECTIVE: To determine the impact of preoperative resting hypercapnia on patient outcome after bilateral lung volume reduction surgery (LVRS). METHODS: We prospectively examined morbidity, mortality, quality of life (QOL), and physiologic outcome, including spirometry, gas exchange, and exercise performance in 15 patients with severe emphysema and a resting PaCO2 of > 45 mm Hg (group 1), and compared the results with those from 31 patients with a PaCO2 of < 45 mm Hg (group 2). RESULTS: All preoperative physiologic and QOL indices were more impaired in the hypercapnic patients than in the eucapnic patients. The hypercapnic patients exhibited a lower preoperative FEV1, a lower diffusing capacity of the lung for carbon monoxide, a lower ratio of PaO2 to the fraction of inspired oxygen, a lower 6-min walk distance, and higher oxygen requirements. However, after surgery both groups exhibited improvements in FVC (group 1, p < 0.01; group 2, p < 0.001), FEV1 (group 1, p=0.04; group 2, p < 0.001), total lung capacity (TLC; group 1, p=0.02; group 2, p < 0.001), residual volume (RV; group 1, p=0.002; group 2, p < 0.001), RV/TLC ratio (group 1, p=0.03; group 2, p < 0.001), PaCO2 (group 1, p=0.002; group 2, p=0.02), 6-min walk distance (group 1, p=0.005; group 2, p < 0.001), oxygen consumption at peak exercise (group 1, p=0.02; group 2, p=0.02), total exercise time (group 1, p=0.02; group 2, p=0.02), and the perceived overall QOL scores (group 1, p=0.001; group 2, p < 0.001). However, because the magnitude of improvement was similar in both groups, and the hypercapnic group was more impaired, the spirometry, lung volumes, and 6-min walk distance remained significantly lower post-LVRS in the hypercapnic patients. There was no difference in mortality between the groups (p=0.9). CONCLUSIONS: Patients with moderate to severe resting hypercapnia exhibit significant improvements in spirometry, gas exchange, perceived QOL, and exercise performance after bilateral LVRS. The maximal achievable improvements in postoperative lung function are related to preoperative level of function; however, the magnitude of improvement can be expected to be similar to patients with lower resting PaCO2 levels. Patients should not be excluded from LVRS based solely on the presence of resting hypercapnia. The long-term benefit of LVRS in hypercapnic patient remains to be determined.     

网格技术在党校图书馆2．0中的运用

网格技术的出现，催生了图书馆2．0这种全新的信息和知识管理形态。使需要运用知识的人们，能够通过网格技术迅速的较为准确些找到自己所需要的知识点。网格技术使知识有了自我产生的可能。为了使知识有序生长。我们图书馆人面临的是难得的机遇和全新的挑战。本文试图对运用网格技术，建立知识推介系统，为党校的教学科研服务作一些探讨。     

Evidence for repression of IL-2 gene activation in anergic T cells

The induction of clonal anergy in a T cell inhibits IL-2 secretion because of the development of a proximal signal transduction defect. Fusion of anergic murine T cells to human Jurkat T leukemia cells and formation of heterokaryons failed to result in a complementation of this signaling defect and restoration of murine IL-2 mRNA inducibility. Instead, signal transduction to the human IL-2 gene became disrupted. Heterokaryons formed by the fusion of anergic murine T cells to normal murine T cells also failed to accumulate intracellular IL-2 protein in response to stimulation either with the combination of CD3 and CD28 mAbs or with ionomycin plus a protein kinase C-activating phorbol ester. The results argue against a loss-of-function signaling defect as the sole basis for clonal anergy induction and document the presence of a dominant-acting repressor molecule that inhibits signal transduction to the IL-2 gene within viable anergic T cells.     

加快高性能高质量高可靠性产品发展为装备制造业提供全程服务

我国改革开放30年,国民经济快速稳定发展,1978-2007年GDP平均增长9.896.进入新世纪GDP增长加速,2003-2007平均增长10.6%.表1为2000年后GDP增长情况.随着国民经济发展,固定资产投资快速增长,而我国机床工业随着国民经济(特别是固定资产投资)增长而快速增长.