Metastasis of malignant melanoma of the nasal mucosa to the small intestine

Malignant melanoma of the mucous membranes is rare and has a very poor prognosis. When localized in the nose, the tumor becomes apparent late in the course of the disease with nasal obstruction and epistaxis. Distant metastases are uncommon, but any organ of the body can be involved. A case of a malignant melanoma of the nasal mucosa with metastasis to the small intestine is presented, and the natural history of the metastatic disease is discussed.     

Intellectual deficits after transient tyrosinemia in the term neonate

An analysis was made of the obstetric history of 1,360 patients who were delivered in 1971. It involved 3,185 pregnancies. The aim of the study was to evaluate the risk of spontaneous termination of the pregnancy, worked out from its demographic aspect. Several ideas are worthy of consideration. The risk of spontaneous intra-uterine death is cumulative, sharply increased by a repetition of such cessation of pregnancy. The same patients often undergo intentional abortion repeatedly. The respective risks of spontaneous and provoked interruption of pregnancy have been studied in greater detail as a function of parity.     

Survey of impaired drivers, fatally injured or surviving, who caused fatal highway accidents in Alberta in 1970-72

In 1970-72, 456 (53.4%) of 854 drivers responsible for a motor vehicle accident in which either they or other persons were killed had been drinking beforehand. Of surviving culpable drivers tested for blood alcohol concentration 81.7% were found to be legally impaired; however, only 24.8% of these drivers were tested. Because surviving culpable drivers pose a possible future hazard to highway safety it is important that data on this group be collected and analysed.     

Very low birth weight children at school age: comparison of neonatal management methods

The outcome of 293 infants born to a geographically defined community and weighing 501-1500 g was investigated. Medical intervention in the newborn period had been avoided. Morbidity was assessed at school age. Of the infants, 236 had been live born in the labour ward of this hospital; of these, 117 (49.6%) died in the neonatal period, one (0.4%) died in the first year, four (1.7%) were untraced, 13 (5.5%) had major handicap, 29 (12.3%) had minor handicap, and 72 (30.5%) were considered to be normal. In terms of survival, handicap, and intellectual with that of infants born over the same period (1963-71) in areas where intensive methods of perinatal care were used. These results imply that postnatal survival and potential of infants of very low birth weight are by no means prejudiced when only experienced nursing care is available.     

Auditory attention in hyperactive children: Effects of stimulant medication on dichotic listening performance.

Administered dichotic digit tasks requiring free report and selective listening, respectively, to 20 6–16 yr old hyperactive children. Ss received methylphenidate before 2 experimental sessions and a placebo before 2 control sessions. The stimulant did not improve free-report performance significantly; rather it facilitated or impaired performance, depending on how it affected the order in which stimuli were reported. Similarly, medication had no effect on overall selective-listening performance, but it increased the difficulty of switching attention from one ear to the other. Results demonstrate that stimulants may act to maintain selective attention and to inhibit channel switching. Listening asymmetry, that is, right-ear superiority, was influenced by task variables but not by stimulant medication. (25 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Use of mini-computers for large scale structural analysis programs

One of the major new developments in computing technology is the mini-computer. This paper presents the results of the implementation of the ANSYS computer program (a large-scale structural analysis system) on a mini-computer.The implementation of ANSYS started with an evaluation of the existing and proposed mini-computer hardware and software systems, relative to a set of criteria derived from the structural software requirements.After benchmarking several systems to compare the claimed performances with the actual performance, the system which most nearly met the requirements for the ANSYS program was selected and ordered.The configuration chosen for this development machine is illustrated and variations from the development configuration which would be desirable for a production environment are discussed.The results of the implementation of ANSYS on the selected mini-computer system are presented. Included in the presentation are run times, run costs, accuracy of results and computer storage requirements.Finally, this paper discusses the future directions which will be pursued in this development effort. Included are discussions of the interface between the mini-computer and a larger central computer, the limits on problem size imposed by core memory and solution time and suggestions for the improvement of the performance of structural problems in a mini-computer environment.