Greater rate of decline in maximal aerobic capacity with age in physically active vs. sedentary healthy women

Using a meta-analytic approach, we recently reported that the rate of decline in maximal oxygen uptake (VO2 max) with age in healthy women is greatest in the most physically active and smallest in the least active when expressed in milliliters per kilogram per minute per decade. We tested this hypothesis prospectively under well-controlled laboratory conditions by studying 156 healthy, nonobese women (age 20-75 yr): 84 endurance-trained runners (ET) and 72 sedentary subjects (S). ET were matched across the age range for age-adjusted 10-km running performance. Body mass was positively related with age in S but not in ET. Fat-free mass was not different with age in ET or S. Maximal respiratory exchange ratio and rating of perceived exertion were similar across age in ET and S, suggesting equivalent voluntary maximal efforts. There was a significant but modest decline in running mileage, frequency, and speed with advancing age in ET. VO2 max (ml . kg-1 . min-1) was inversely related to age (P < 0.001) in ET (r = -0.82) and S (r = -0.71) and was higher at any age in ET. Consistent with our meta-analysic findings, the absolute rate of decline in VO2 max was greater in ET (-5.7 ml . kg-1 . min-1 . decade-1) compared with S (-3.2 ml . kg-1 . min-1 . decade-1; P < 0. 01), but the relative (%) rate of decline was similar (-9.7 vs -9. 1%/decade; not significant). The greater absolute rate of decline in VO2 max in ET compared with S was not associated with a greater rate of decline in maximal heart rate (-5.6 vs. -6.2 beats . min-1 . decade-1), nor was it related to training factors. The present cross-sectional findings provide additional evidence that the absolute, but not the relative, rate of decline in maximal aerobic capacity with age may be greater in highly physically active women compared with their sedentary healthy peers. This difference does not appear to be related to age-associated changes in maximal heart rate, body composition, or training factors.     

Voltage Division Position Sensitive Detectors Based on Photoconductive Materials Part II: Device Performances and Experimental Results

This second section is dedicated to gain more insight into the Voltage Division Position Sensitive Detector described in Part I of this work. Here, the discussion is taken from a design point of view. The linearity and rejection to light intensity variations are described on the practical situation of an incident light beam whose cross sectional dimensions could be negligible to the length of the sensor active area. The noise contribution due to the resistive nature of the detector is taken into account and discussed, too. According to the ideas here depicted, a sensor based on high-quality CVD-diamond film has been fabricated. The experimental results acquired for such specimens, under UV excimer laser or X-ray illumination, confirm the theoretical expectations.     

Modal Identification Study of Vincent Thomas Bridge Using Simulated Wind-Induced Ambient Vibration Data

Abstract:   In this article, wind-induced vibration response of Vincent Thomas Bridge, a suspension bridge located in San Pedro near Los Angeles, California, is simulated using a detailed three-dimensional finite element model of the bridge and a state-of-the-art stochastic wind excitation model. Based on the simulated wind-induced vibration data, the modal parameters (natural frequencies, damping ratios, and mode shapes) of the bridge are identified using the data-driven stochastic subspace identification method. The identified modal parameters are verified by the computed eigenproperties of the bridge model. Finally, effects of measurement noise on the system identification results are studied by adding zero-mean Gaussian white noise processes to the simulated response data. Statistical properties of the identified modal parameters are investigated under an increasing level of measurement noise. The framework presented in this article will allow us to investigate the effects of various realistic damage scenarios in long-span cable-supported (suspension and cable-stayed) bridges on changes in modal identification results. Such studies are required to develop robust and reliable vibration-based structural health monitoring methods for this type of bridge, which is a long-term research objective of the authors.     

GLRT-based adaptive detection algorithms for range-spread targets

We address adaptive detection of a range-spread target or targets embedded in Gaussian noise with unknown covariance matrix. To this end, we assume that cells (referred to in the following as secondary data) that are free of signal components are available. Those secondary data are supposed to possess either the same covariance matrix or the same structure of the covariance matrix of the cells under test. In this context, we design detectors relying on the generalized likelihood ratio test (GLRT) and on a two-step GLRT-based design procedure. Remarkably, both criteria lead to receivers ensuring the constant false alarm rate (CFAR) property with respect to the unknown quantities. A thorough performance assessment of the proposed detection strategies, together with the evaluation of their processing cost, highlights that the two-step design procedure is to be preferred with respect to the plain GLRT. In fact, the former leads to detectors that achieve satisfactory performance under several situations of practical interest and are simpler to implement than those designed resorting to the latter     

Polycyclic aromatic hydrocarbon (PAH) content of soil and olives collected in areas contaminated with creosote released from old railway ties

Simple sample preparation procedures involving sonication and solid phase extraction (SPE), followed by reversed-phase high performance liquid chromatography (HPLC) and spectrofluorometric detection, were used to analyse polycyclic aromatic hydrocarbons (PAHs) in soil and olives collected in areas contaminated with creosote-treated railway ties. Very high PAH contents (with amounts ranging from 114.7 to 2157.2 and from 167.3 to 3121.8 microg kg(-1) dry weight for total light PAHs and total heavy PAHs, respectively) were found in soil sampled up to 1 m from the source of contamination. The PAH load decreased rapidly with the distance from the railway ties. High amounts of light PAHs, up to 6359.9 microg kg(-1), were also found in oil extracted from olives collected in a rural area where old railway ties were stored. No appreciable transfer of heavy PAHs and benzo[a]pyrene was observed in oil samples.     

Variety differentiation of virgin olive oil based on n-alkane profile

An on-line LC–GC method was used to assess the n-alkane composition of 40 olive oil samples obtained from three different cultivars from a restricted grove zone in Croatia. Olive samples were handpicked at three different ripening stages during four consecutive years. No significant differences were found in relation to the variable “period of harvesting”, while the effects “variety” and “year” as well as their interaction caused significant differences for most of the n-alkane components (p0.05). Despite the influence of the production year, linear discriminant analysis based on the n-alkane components was able to correctly identify the variety of 97.5% of the samples.     

The genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 reside on a large plasmid whose loss leads to degeneration of the strain

Degeneration is the process whereby Clostridium acetobutylicum ATCC 824 loses the capacity to produce acetone and butanol after repeated vegetative transfers or in continuous culture. Two degenerate mutants (M5 and DG1) of C. acetobutylicum ATCC 824 do not contain the four genes (ctfA, ctfB, adc, and aad) for acetone and butanol formation. Strain ATCC 824 contains a 210-kb plasmid (pSOL1) which is absent in M5 and DG1. pSOL1 carries the four acetone and butanol formation genes. A restriction map of pSOL1 was constructed by using ApaI, SmaI, SstII, and NarI digestions. M5 and DG1 could be complemented for acetone and butanol formation by expressing the corresponding genes (ctfA, ctfB, and adc for acetone; aad for butanol) on the plasmid. Degeneration of this strain thus appears to be the result of pSOL1 loss.