Do the high-frequency indexes of HRV provide a faithful assessment of cardiac vagal tone? A critical theoretical evaluation

When spectral analysis of the heart rate (HR) signal is performed, it is quite common to attribute the HF indexes of heart rate variability (HRV) to cardiac vagal control. The paradigm underlying this attribution states that changes in cardiac vagal outflow correspond to a proportional change in respiratory sinus arrhythmia (RSA). However, recent studies have demonstrated that variations in these indexes do not necessarily reflect proportional changes in vagal tone. The current study provides a theoretical evaluation of the relationship between mean HR, RSA, and cardiac vagal tone. This evaluation is based on a theoretical model, which quantifies the differential effects of vagal blockade by a competitive muscarinic antagonist on the HF indexes of HRV. The model relies on several assumptions that reflect the basic physiology of the sinoatrial (SA) node, as well as pharmacological relations that describe agonist/antagonist equilibrium at the SA receptors. The mathematical framework of this model is the integral-pulse-frequency-modulation (IPFM) process, and its derivations lead to a specific expressions for the dependence of HF and mean HR on the level of vagal blockade. These expressions provide a new insight into the relationship between mean HR, RSA, and vagal tone, and explain conflicting experimental results previously published.     

Approximate belief updating in max-2-connected Bayes networks is NP-hard

A max-2-connected Bayes network is one where there are at most 2 distinct directed paths between any two nodes. We show that even for this restricted topology, null-evidence belief updating is hard to approximate.     

Unitary and non-unitary manipulations of qubit-bath entanglement: non-Markov qubit cooling

Initialization of quantum logic operations makes it imperative to cool down the information-carrying qubits as much and as fast as possible, so as to purify their state, or at least their ensemble average. Yet, the limit on the speed of existing cooling schemes is either the duration of the qubit equilibration with its bath or the decay time of an auxiliary state to one of the qubit states. Here we show that highly-frequent phase-shifts or measurements of the state of thermalized qubits can be designed to affect the qubit-bath entanglement so that the qubits undergo cooling, well before they re-equilibrate with the bath and without resorting to auxiliary states. These processes can be used in principally novel, advantageous, cooling schemes to assist quantum logic operations.     

If it looks like a spammer and behaves like a spammer,it must be a spammer: analysis and detection of microblogging spam accounts

Spam in online social networks (OSNs) is a systemic problem that imposes a threat to these services in terms of undermining their value to advertisers and potential investors, as well as negatively affecting users’ engagement. As spammers continuously keep creating newer accounts and evasive techniques upon being caught, a deeper understanding of their spamming strategies is vital to the design of future social media defense mechanisms. In this work, we present a unique analysis of spam accounts in OSNs viewed through the lens of their behavioral characteristics. Our analysis includes over 100 million messages collected from Twitter over the course of 1 month. We show that there exist two behaviorally distinct categories of spammers and that they employ different spamming strategies. Then, we illustrate how users in these two categories demonstrate different individual properties as well as social interaction patterns. Finally, we analyze the detectability of spam accounts with respect to three categories of features, namely content attributes, social interactions, and profile properties.     

Stirring the hearts of followers: Charismatic leadership as the transferal of affect.

In 2 studies, the authors found that leader charisma was positively associated with followers' positive affect and negatively associated with followers' negative affect. The authors hypothesized that leaders' positive affect, positive expression, and aroused behavior will mediate these relationships. The results of their lab study suggest that leaders' positive expression and aroused behavior mediated these relationships. A field study showed that firefighters under the command of a charismatic officer were happier than those under the command of a non-charismatic officer and that these relationships were mediated by the leader's positive affect and a tendency to express positivity. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Software monitoring with controllable overhead

We introduce the technique of software monitoring with controllable overhead (SMCO), which is based on a novel combination of supervisory control theory of discrete event systems and PID-control theory of discrete time systems. SMCO controls monitoring overhead by temporarily disabling monitoring of selected events for as short a time as possible under the constraint of a user-supplied target overhead o _t. This strategy is optimal in the sense that it allows SMCO to monitor as many events as possible, within the confines of o _t. SMCO is a general monitoring technique that can be applied to any system interface or API. We have applied SMCO to a variety of monitoring problems, including two highlighted in this paper: integer range analysis, which determines upper and lower bounds on integer variable values; and non-accessed period detection, which detects stale or underutilized memory allocations. We benchmarked SMCO extensively, using both CPU- and I/O-intensive workloads, which often exhibited highly bursty behavior. We demonstrate that SMCO successfully controls overhead across a wide range of target overhead levels; its accuracy monotonically increases with the target overhead; and it can be configured to distribute monitoring overhead fairly across multiple instrumentation points.     

Carbon cycling in a zero-discharge mariculture system

Interest in mariculture systems will rise in the near future due to the decreased ability of the ocean to supply the increasing demand for seafood. We present a trace study using stable carbon and nitrogen isotopes and chemical profiles of a zero-discharge mariculture system stocked with the gilthead seabream (Sparus aurata). Water quality maintenance in the system is based on two biofiltration steps. Firstly, an aerobic treatment step comprising a trickling filter in which ammonia is oxidized to nitrate. Secondly, an anaerobic step comprised of a digestion basin and a fluidized bed reactor where excess organic matter and nitrate are removed. Dissolved inorganic carbon and alkalinity values were higher in the anaerobic loop than in the aerobic loop, in agreement with the main biological processes taking place in the two treatment steps. The δ¹³C of the dissolved inorganic carbon (δ¹³C_DIC) was depleted in ¹³C in the anaerobic loop as compared to the aerobic loop by 2.5-3‰. This is in agreement with the higher dissolved inorganic carbon concentrations in the anaerobic loop and the low water retention time and the chemolithotrophic activity of the aerobic loop. The δ¹³C and δ¹⁵N of organic matter in the mariculture system indicated that fish fed solely on feed pellets. Compared to feed pellets and particulate organic matter, the sludge in the digestion basin was enriched in ¹⁵N while δ¹³C was not significantly different. This latter finding points to an intensive microbial degradation of the organic matter taking place in the anaerobic treatment step of the system.