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排序方式: 共有884条查询结果,搜索用时 15 毫秒
91.
92.
Recent advances in image reconstruction, coil sensitivity calibration, and coil array design for SMASH and generalized parallel MRI. 总被引:4,自引:0,他引:4
Daniel K Sodickson Charles A McKenzie Michael A Ohliger Ernest N Yeh Mark D Price 《Magma (New York, N.Y.)》2002,13(3):158-163
Parallel magnetic resonance imaging (MRI) techniques use spatial information from arrays of radiofrequency (RF) detector coils to accelerate imaging. A number of parallel MRI techniques have been described in recent years, and numerous clinical applications are currently being explored. The advent of practical parallel imaging presents various challenges for image reconstruction and RF system design. Recent advances in tailored SiMultaneous Acquisition of Spatial Harmonics (SMASH) image reconstructions are summarized. These advances enable robust SMASH imaging in arbitrary image planes with a wide range of coil array geometries. A generalized formalism is described which may be used to understand the relations between SMASH and SENSE, to derive typical implementations of each as special cases, and to form hybrid techniques combining some of the advantages of both. Accurate knowledge of coil sensitivities is crucial for parallel MRI, and errors in calibration represent one of the most common and the most pernicious sources of error in parallel image reconstructions. As one example, motion of the patient and/or the coil array between the sensitivity reference scan and the accelerated acquisition can lead to calibration errors and reconstruction artifacts. Self-calibrating parallel MRI approaches that address this problem by eliminating the need for external sensitivity references are reviewed. The ultimate achievable signal-to-noise ratio (SNR) for parallel MRI studies is closely tied to the geometry and sensitivity patterns of the coil arrays used for spatial encoding. Several parallel imaging array designs that depart from the traditional model of overlapped adjacent loop elements are described. 相似文献
93.
BACKGROUND: In this study, we describe the development of a novel experimental system in which rejection of porcine skin grafts by human peripheral blood cells can be studied directly in vivo in immunodeficient mice. METHODS: To construct a small animal model of discordant xenograft rejection, recombinase-activating gene-deficient mice (R-) lacking both mature B and T cells were grafted with porcine skin grafts and administered, by adoptive cell transfer, human cells stimulated in vitro with irradiated porcine peripheral blood cells to create Hu-R- mice. RESULTS: R- mice accepted porcine skin grafts indefinitely without the need for immunosuppression. In contrast, Hu-R- mice were able to reject porcine skin grafts. Immunohistochemical analysis of rejecting skin grafts revealed the accumulation of human T cells around dermal porcine vessels and focally in the epidermis. Graft rejection was manifested by vascular endothelial cell proliferation, edema at the dermal-epidermal border, and perivascular hemorrhage. The tissue damage observed in the rejecting grafts was similar to that observed in delayed primate anti-porcine cell-mediated rejection of vascularized organ xenografts. CONCLUSIONS: The development and characterization of a small animal model, to study cellular immune responses of human cells to discordant xenografts in vivo, should provide a convenient means for asking mechanistic questions related to discordant xenotransplantation, and may also provide a practical system for testing new approaches designed to prevent xenograft rejection. 相似文献
94.
Campbell P.M. Greub H.J. Garg A. Steidl A. Carlough S. Ernest M. Philhower R. Maier C. Kraft R.P. McDonald J.F. 《Very Large Scale Integration (VLSI) Systems, IEEE Transactions on》1998,6(1):52-55
A digital voltage-controlled oscillator (VCO) is described which uses frequency multiplication and division to achieve very wide bandwidth. The VCO uses current-mode logic and does not require reactive elements such as inductors, capacitors or varactors. A novel, fully symmetric exclusive-OR (XOR) circuit was developed which uses product pairs and emitter-coupled logic. To achieve the highest performance possible, the critical path is symmetric and special physical design techniques were developed to promote matched-capacitance. The maximum measured frequency was 13.66 GHz. The chip occupies 1.9 mm×1.6 mm and dissipates 2.45 W at a supply voltage of -6.0 V. With a measured frequency range from 1.25 to 13.66 GHz, this circuit has the widest bandwidth reported in the literature for any VCO, digital or analog 相似文献
95.
During spatial navigation, women typically navigate an environment using a landmark strategy, whereas men typically use an orientation strategy. To examine the as yet unknown effects of sexual orientation on these normative sex differences, this study required 80 healthy heterosexual and homosexual adult men and women to provide directions from experimental maps for 4 routes. The frequency and type of strategy used by each participant were computed. Expected sex differences were demonstrated, and a robust cross-sex shift was shown by homosexual men in using landmarks. This remained after controlling for differences in mental rotation, directional sense, and general intelligence. The findings may limit the number of putative neurodevelopmental pathways responsible for sex differences in navigation strategy utility. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
96.
Arvind Narurkar Pai-Chang Sheen Ernest L. Hurwitz Matthew A. Augustine 《Drug development and industrial pharmacy》1987,13(2):319-328
The particle size reduction of chlorthalidone by fluid energy milling, Alpine milling and Fitzpatrick milling were evaluated. The desired particle size was achieved by both the fluid energy milling and Alpine milling processes. Alpine mil1ing, however, is a more complex process and is susceptible to product decomposition, whereas fluid energy milling is a simple and efficient process without any risk of product decomposition. The desired particle size cannot be achieved by Fitzmilling because of the low probability of impaction force on particles. The dissolution rate of the chlorthalidone from chlorthalidone/propranolol hydrochloride tablets (25/80 mg) prepared with fluid energy milled chlorthalidone was significantly better than the tablets prepared with Fitzpatrick - milled chlorthalidone. The minimum effective specific surface area of chlorthalidone needed for maximum dissolution in water was found to be around 3.5 m2/g. 相似文献
97.
A. Ernest MacGee 《Journal of the American Ceramic Society》1928,11(11):858-867
Porosity, crushing strength, elasticity, specific gravity, transverse strength, thermal expansion, impact strength, and resistance to heat shock were determined on five glass tank block refractory bodies. Ability to resist heat shock was successfully predicted from the elasticity, transverse strength, thermal diffusivity, and thermal expansion values. 相似文献
98.
Grych John H.; Jouriles Ernest N.; Swank Paul R.; McDonald Renee; Norwood William D. 《Canadian Metallurgical Quarterly》2000,68(1):84
Children exposed to interparental violence have been characterized by an array of psychological problems, but findings regarding the precise nature of these problems have been inconsistent. This study used cluster analysis to determine whether distinct patterns of adjustment could be identified in 228 8- to 14-year-old children residing in battered women's shelters. Five such patterns emerged: multiproblem–externalizing, multiproblem–internalizing, externalizing, mild distress, and no problems reported. This solution was cross-validated in independent halves of the sample and was similar for boys and girls. Differences among the clusters on relevant family and demographic variables were examined, and it was found that the clusters could be distinguished on the basis of the frequency of children's exposure to interparental violence, parent–child aggression, and children's appraisals of interparental conflict. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
99.
Examined racial E effects in counseling-like interviews employing the verbal operant-conditioning paradigm. The general objective was to determine whether significant differences in the conditionability of 12 Black and 12 White female college students, as measured by their emission of positive and negative self-reference emotional affect statements, would obtain when the verbal reinforcement was provided by 2 Black and 2 White Es. A postexperimental inquiry assessed Ss' perceptions of the interviews and their level of awareness of the Es' to influence their verbal behavior. While no definitive conclusions were reached, this study demonstrates that the verbal operant-conditioning paradigm can be used to investigate racial effects on verbal behavior in the counseling interview. Through the use of multiple, biracial Es and Ss, this study goes a step further than other verbal operant-conditioning studies that have explored racial E effects. The absence of significant differences in the E-S racial interaction suggests that race, per se, may not be the most important variable in the E-S (or counselor-client) relationship. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
100.