Guanine and plasmid DNA binding of mono- and trinuclear fac-[Re(CO)3]+ complexes with amino acid ligands

We have synthesized and fully characterized four new complexes comprising the fac-[Re(CO)3]+ moiety and the ligands NH3, L-proline (Pro), or N,N-dimethylglycine (dmGly). The reaction of [Re(H2O)3(CO)3]+ with the two amino acids gives trinuclear complexes of general formula [Re(L)(CO)3]3 (where L = amino acid). We have studied the in vitro behavior of these compounds with guanine and DNA in order to understand whether the cytotoxicity exhibited by certain rhenium complexes based on the fac-[Re(CO)3]+ core is due to the formation of nucleobase complexes and inter- or intrastrand links between DNA bases. We have performed model studies with guanine and studied the structural effects induced by different rhenium(I) tricarbonyl complexes on PhiX174 plasmid DNA by electrophoretic methods. Our results show that rhenium complexes with two available coordination sites interact with plasmid DNA to form a stable adduct that is likely to involve two bases.     

Positive holes in magnesium oxide. Correlation between magnetic, electric, and dielectric anomalies

Magnetic susceptibility measurements of high purity MgO single crystals (<50-wt. ppm transition metals) by means of a vibrating-sample magnetometer shows an anomaly at 800 K. At the same temperature the electric conductivity increases anomalously, the static dielectric constant epsilon increases from 9 to approximately 150, a pronounced positive surface charge appears, and Fe2+ in the MgO matrix oxidizes to Fe3+. The data are consistent with O2(2-) (peroxy) defects, representing self-trapped, spin-paired positive holes at Mg2+ vacancy sites. Diamagnetic at low temperatures, the holes start to decouple their spins > 600 K, probably forming at first V0 centers (two O- at an Mg2+ vacancy), then V- centers (single O- at an Mg2+ vacancy), and releasing mobile O- states. These O- represent itinerant charge carriers on acceptor levels near the O 2p-dominated valence band and conduct by O- /O2- valency fluctuations. The O- concentration is of the order of 8 X 10(19) cm-3.     

THE EFFECTS OF SPUTTERING POWER ON STRUCTURE AND ELECTRICAL PROPERTIES OF Cu FILMS

1. IntroductionCu filnls are very pron1isillg for electronic devices because of both high electromigrationresista11ce alld high electrical conductivity['--']. For a sputter-deposited film, base pressure,deposition rate, substrate temperature and energetic…     

金属液流的惰性气体屏蔽新技术

<正> 一、引言中间包和钢包钢流的重氧化,是连铸和铸锭钢材非金属夹杂物的主要来源(中间包钢流相对于其体积则有更大表面积).冶金工作者设计出来用某种类型惰性气体,例如氩气、氮气,或运用机械屏蔽法,作为中间包到铸模间钢流的保护装置.机械屏蔽的主要缺点,是不能充分地观察钢液流;而气体制品或化学惰性气体屏蔽系统净化浇注,则可     

HEAT TRANSFER ANALYSIS DURING ROLLING OF THIN SLAB IN CSP

A mathematical model has been built to numerically predict the thermal history of thin slab during CSP （compact strip process） rolling. To estimate the temperature distribution in the slab mare accurately, the mathematical model combines heat transfer in the slab, in the roll, and at the roll-slab interface during bite. The numerical results agree with on-site running data, which proves the reliabili~, of the mathematical model. The results show that roll chilling has a significant effect on the temperature distribution in the slab.     

氮气氛用于高碳钢无脱碳退火

中、高碳钢的退火工作者长期以来意识到他们面临的问题是:用户并不总是根据最好的冶金科学,而是根据由于缺乏控制整个退火条件常常不可避免的出现一些互相矛盾的结果提要求。尽管我们常常力图要更好地了解在影响渗碳、脱碳和碳黑的化学反应中所发生的情况,但由于退火气氛的供应不能解决前面所提到的问题。例如:在理想情况下,当钢在退火过程中加热和冷却时,纯氮将阻止钢中的化学成份的改变。但实际上退火炉中通常会有一些氧存在,这种氧或者是泄漏空气的游离氧,或者是氧化物、水和二氧化碳的化合态氧。     

160吨电渣重熔钢锭的生产和加工

重熔设备的原理。氢、铝、硫含量和重熔时间的关系。熔池深度和钢锭高度的关系。电渣重熔的26NiCrMoV14 5钢和26NiCrMoV11 5钢转子的机械能性,FATT和NDTT。对直径达1800mm的锻件和重熔时工艺控制的展望。     

D2工具钢在气淬和回火过程中的各向异性畸变

分别使用铸造试样及两种不同锻造程度的锻件试样，对高合金冷作模具钢D2在气淬和回火过程中的畸变行为进行了研究。试验结果表明，铸造试样的畸变是等向性的，而锻造试样的畸变显然呈各向异性。各向异性畸变程度随奥氏体化温度的升高而增加。在本试验范围内，不同的锻造程度对各向异性的畸变程度影响不大。回火后各向异性畸变程度有所降低。使用测膨胀方法及金相检验探讨了产生各向异性畸变的可能机制。     

用声学技术监视和控制放电加工过程

前言为了监视和控制电火花加工过程,就需要鉴别放电特征并区分出现有效放电和电弧的条件。加工过程中常须要确定加在电极和工件之间的最佳脉冲周期和间隔比。这些参数随工件材料和加工的形状而定。其它要求最佳化的参数是放电间隙大小,电极进给速度以及脉冲电压和电流。这些参数是互相联系制约的。