低剂量率γ射线杀伤肿瘤细胞机制的实验研究

用60Co源以1Gy/min剂量率照射Hela细胞,剂量分别为1、2、5、10、15Gy.用AnnexinV和PI双染法观察凋亡细胞形态;DNA梯形条带证实凋亡存在;克隆形成分析细胞增殖能力.结果显示:(1)Hela细胞凋亡率随照射剂量和时间的增加呈上升趋势,照射后168h组各剂量点凋亡率高于其他各时间组.2Gy以下时凋亡率改变不大,达5Gy时凋亡率显著增加,且达峰值(72.57±2.04)%(P＜0.001).(2)早期凋亡细胞,PS外翻,胞膜呈绿色荧光圈.凋亡晚期出现Annexin V-FITC及PI染色均阳性的外绿内红的细胞图像.坏死细胞则为红色.(3)凋亡细胞碎片呈"梯状"条带.(4)1Gy/min的剂量率照射,剂量为2-15Gy,克隆形成率由(58.95±0.36)%降至(1.67±0.35)%(P＜0.001).表明低剂量率γ射线照射可诱导Hela细胞凋亡,其凋亡率与照射剂量相关,在5Gy时凋亡率最高.     

Development and hot-melt impregnation of a model controlled flow prepreg system

A controlled-flow epoxy-based model prepreg resin system was developed. The formulation of the model controlled-flow resin was designed from performance information obtained from a commercially available controlled-flow resin, presently used in the aircraft industry. Thermoanalytical techniques including rheometry were used to provide the necessary information to develop the model system along with a formulation methodology developed by Seferis and co-workers. The model resin formulation, which was a combination of tetraglycidyl ether of methylenedianiline (TGMDA), diglycidyl ether of bisphenol-A (DGEBA), carboxyl-modified butadiene/acrylonitrile rubber (CMBN), carboxyl-terminated butadiene/acrylonitrile rubber (CTBN), bisphenol-A (BPA), diaminodiphenyl sulfone (DDS), and dicyandiamide (DICY), was hot-melt impregnated into unidirectional carbon fibers on a laboratory scale hot-melt prepreg machine. A two-parameter, three-level design of experiments was performed on the prepreg processing parameters in which impregnation temperature and pressure were varied. Thus, a total of nine different experimental prepregs were produced and characterized by resin content, extent of impregnation, and tack. The results from the characterization of the nine experimental prepregs are compared with the effects of the prepreg processing conditions. These results are also compared with the results generated for the commercial controlled-flow resin. Collectively, this work provides a fundamental basis by which the analysis and rational utilization of controlled-flow matrix prepregs can be effected.     

A thermodynamically consistent framework for non-isothermal modelling of local heat generation and electromotive force in SOFC single electrodes

Mathematical models for single electrode reversible heat and non-isothermal electromotive force (EMF) of a solid oxide fuel cell (SOFC) are developed. These models estimate the volumetric reversible heat generation and EMF of electrochemical reactions, within each electrode at local conditions of temperature and pressure, based on entropy change of half reactions. The resulting equations are thermodynamically consistent. They inherently obey the conservation of energy law as the electrochemical energy released added to the heat of reactions at each electrode equate the enthalpy change of the reacted species. The equations are implemented to model electrodes in a tubular micro- solid oxide fuel cell (TμSOFC). The thermodynamic consistency of the model is numerically confirmed as the enthalpy of the reactants equates the electric energy released by the cell plus the sum of electrode heats plus electrolyte Ohmic heat. The effect of thermal gradients on the cell's overall EMF is found to be negligible. The reversible and irreversible heat generation of each electrode are distinguished. Overall, the anode is found to be endothermic, and the cathode exothermic.     

基于采动和承压水作用下断层突水关键路径的力学分析

 断层突水是煤矿典型的动力灾害,是煤岩体在采动和承压水共同作用下失稳破坏过程。论文针对导水断层缩短了煤层和含水层距离特点,建立了断层突水的关键路径力学模型。将极限平衡理论和尖点突变理论引入断层突水分析,建立了承压水及采动影响下断层突水关键部位失稳破坏模型,获得了断层突水的力学判据,以及防突煤柱预留临界宽度。同时分析了断层参数、煤柱参数对突水条件的影响规律     

Mechanisms and Kinetics of Reduction of Solid NiO in CO/CO2 and CO/Ar Gas Mixtures

Metallurgical and Materials Transactions B - Experimental studies have been carried out on the reduction of dense nickel oxide in CO/CO2 and CO/Ar gas mixtures at temperatures between...     

Controlled Solidification of Liquids Within the SFC Primary Phase Field of the “Fe2O3”-CaO-SiO2 System in Air

Metallurgical and Materials Transactions B - To provide fundamental information on the phases and microstructures formed during sintering, a liquid with a bulk composition within the silico ferrite...     

A rigorous proof of MIMO channel capacity’s increase with antenna number

It is well known that adding more antennas at the transmitter or at the receiver may offer larger channel capacity in the multiple-input multiple-output（MIMO） communication systems. In this letter, a simple proof is presented for the fact that the channel capacity increases with an increase in the number of receiving antennas. The proof is based on the famous capacity formula of Foschini and Gans with matrix theory.     

Facilitating a benign attentional bias reduces negative thought intrusions.

The causal role of biased attention in worry was investigated in an experiment in which high worriers were assigned either to a condition requiring attention to nonthreatening words and text while ignoring worry-related material or to a mixed-attention control condition. The former procedure led to fewer negative thought intrusions in a worry test (as rated by both participants and an assessor) than did the control condition. These findings suggest that attentional bias plays a causal role in worry and that its modification can reduce excessive worry. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Optical Spectroscopy of Inorganic Solids

Abstract

The inhomogeneity of thin films of ZrO₂ and TiO₂ was reduced by ion beam bombardment with mixed argon and oxygen as a working gas during deposition. The inhomogeneities of the films were calculated from transmission monitoring curves. The optimum ion beam voltage and ion beam current density are 900 V and 12 μA cm^?2 for TiO₂ film.