A dirofilaria granulom of the lid and the orbid (author''s transl)

The desire for an improvement in appearance and the strong emphasis currently placed on contemporary hair styles for men, have increased the number of requests for hair transplants during the past decade. Esthetics is probably the strongest motivation.     

Increased dynamic stiffness of trabeculae carneae from senescent rats

Dynamic stiffness was measured in both adult and senescent Wistar rats using sinusoidal length perturbations from 17 to 40 Hz, superimposed on isometric contractions at low and below Lmax. The slope of the stiffness-tension relationship was found to be increased in senescent muscles of both sexes and at two different temperatures. The age dependence of the slope was independent of resting muscle length. The slope also exhibited frequency dependence and hysteresis that indicates the presence of viscoelasticity during activation. No age dependence was seen in peak active tension, peak dT/dt, or resting stiffness. The findings of this study, taken together with other studies that have shown a decreased shortening ability in the senescent muscle, explain in part the maintenance of active tension development in the face of decreased shortening ability associated with the senescent muscle.     

Selected ion monitoring assay for the bronchodilator pirbuterol

A selected ion monitoring assay has been developed to measure plasma levels of the bronchodilator pirbuterol in animals and man. Pirbuterol is extracted from plasma with acetone + potassium carbonate and after further purification is converted to its trimethylacetyl derivative. With the use of the stable isotope labeled internal standard, pirbuterol-d9, precisions of 10% and 6% were achieved at plasma concentrations of 1 and 20 ng ml-1, respectively. The synthesis of the deuterium labeled internal standard is described.