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81.
Squamous cell carcinoma of the tonsil has a relatively poor prognosis. Aggressive surgery, radiation therapy and combinations of irradiation and surgery have been employed but there exists some controversy about the efficacy of these treatment modalities. The purpose of this paper is to compare the efficacy of treatment between the surgery followed by radiation therapy and the preoperative radiation therapy followed by surgical resection. The medical records of 33 patients treated for squamous cell carcinoma of the tonsil at the Department of Otolaryngology-Head and Neck Surgery, Korea University Hospital between 1989-1993 were reviewed retrospectively. None of the patients were stage I, but stage II, III, and IV were four, five, and 24 patients, respectively. There were 30 males and three females. The most common histopathology was moderately differentiated squamous cell carcinoma (20/33). The 13 patients treated initially with surgery had an overall three-year survival rate of 38.5%, and the rate for the 20 patients treated initially with radiation was 40%. The main pattern of treatment failure was a local recurrence and neck metastases, and pathologic differentiation thought to be an important prognostic factor. Complications are fewer in patients treated initially with surgery (23.1%) than patients initially treated with radiation (50.0%). There is no difference in the efficacy between the two therapeutic groups.  相似文献   
82.
The effect of matrix microstructure on the stress-controlled fatigue behavior of a 2080 Al alloy reinforced with 30 pct SiC particles was investigated. A thermomechanical heat treatment (T8) produced a fine and homogeneous distribution of S′ precipitates, while a thermal heat treatment (T6) resulted in coarser and inhomogeneously distributed S′ precipitates. The cyclic and monotonic strength, as well as the cyclic stress-strain response, were found to be significantly affected by the microstructure of the matrix. Because of the finer and more-closely spaced precipitates, the composite given the T8 treatment exhibited higher yield strengths than the T6 materials. Despite its lower yield strength, the T6 matrix composite exhibited higher fatigue resistance than the T8 matrix composite. The cyclic deformation behavior of the composites is compared to monotonic deformation behavior and is explained in terms of microstructural instabilities that cause cyclic hardening or softening. The effect of precipitate spacing and size has a significant effect on fatigue behavior and is discussed. The interactive role of matrix strength and SiC reinforcement on stress within “rogue” inclusions was quantified using a finite-element analysis (FEA) unit-cell model.  相似文献   
83.
84.
We present a compact diode-pumped single-frequency single-polarization erbium-doped fiber laser with fiber Bragg gratings (FBGs) written in the active fiber itself. The single-polarization regime was obtained by applying uni-axial stress to one of the two FBGs forming the cavity. The laser is shown to operate in two regimes-quasi-continuous-wave regime with a few-percent of modulation in the output power and a giant-pulse regime accessible under sinusoidal pump modulation.  相似文献   
85.
86.
A key challenge in the design of real-time wireless multimedia systems is the presence of fading coupled with strict delay constraints. A very effective answer to this problem is the use of diversity achieving techniques to overcome the fading nature of the wireless channels caused by the mobility of the nodes. The mobility of the nodes gives rise to the need of cooperation among the nodes to enhance the system performance. This paper focuses on comparing systems that exhibit diversity of three forms: source coding diversity, channel coding diversity, and user cooperation diversity implemented through multihop or relay channels with amplify-and-forward or decode-and-forward protocols. Commonly used in multimedia communications, performance is measured in terms of the distortion exponent, which measures the rate of decay of the end-to-end distortion at asymptotically high signal-to-noise ratio (SNR). For the case of repetition coding at the relay nodes, we prove that having more relays is not always beneficial. For the general case of having a large number of relays that can help the source using repetition coding, the optimum number of relay nodes that maximizes the distortion exponent is determined in this paper. This optimum number of relay nodes will depend on the system bandwidth as well as the channel quality. The derived result shows a trade-off between the quality (resolution) of the source encoder and the amount of cooperation (number of relay nodes). Also, the performances of the channel coding diversity-based scheme and the source coding diversity-based scheme are compared. The results show that for both relay and multihop channels, channel coding diversity provides the best performance, followed by the source coding diversity.  相似文献   
87.
Salmonellosis is the 2nd most common cause of human bacterial food poisoning and can be acquired from meat or eggs, either via direct consumption or cross‐contamination in the kitchen. The European Commission has set the criteria to control Salmonella infections within the poultry sector and it is proposed that the swine sector should follow. Pork is considered, after eggs, the major source of infection in humans in the EU, with Salmonella typhimurium, including monophasic strains, being frequently implicated. Good control measures at the farm level are likely to correspond with lower prevalence of Salmonella infection and, subsequently, a reduction of cross‐contamination of carcasses processed at the slaughterhouse and a reduction in human salmonellosis. This review focuses on biosecurity measures in pig farms that can help to control important pig diseases at the same time as reducing the within‐herd prevalence of Salmonella. This information is likely to provide an economic incentive for farmers to apply improved general standards of farm biosecurity and hygiene management that would have a positive impact in food safety.  相似文献   
88.
The laminar burning velocity of syngas mixtures has been studied by various researches. However, most of these studies have been conducted in atmospheric conditions at sea level. In the present study, the effect of sub atmospheric pressure was evaluated on the laminar burning velocity for a mixture of H2, CO and N2 (20:20:60 vol%) in real sub atmospheric condition. The measurements was conducted in an altitude of 2130 m.a.s.l (0.766 atm) and 21 m.a.s.l (0.994 atm) to evaluate the effect of pressure, the temperature and relative humidity were controlled using an air conditioning unit and was maintained in 295 ± 1 K and 62.6 ± 2.7% respectively. The Flames were generated using contoured slot-type nozzle burner, and an ICCD camera was used to capture chemiluminescence emitted by OH∗-CH∗ radicals present in the flame and thus obtain the flame front and determinate the laminar burning velocity using the angle method. The experimental results were compared with numerical calculations, conducted using the detailed mechanisms of Li et al. and the GRI-Mech 3.0. It was found that the laminar burning velocity increases at lower pressure, for an equivalence ratio of 1.1, the laminar burning velocity increases by almost 23% respect to the sea level conditions.  相似文献   
89.
The flow in a recess of a hydrostatic journal bearing is studied in detail. The Navier-Stokes equations for the laminar flow of an incompressible liquid are solved numerically in a two-dimensional plane of a typical bearing recess. Pressure- and shear-induced flows, as well as a combination of these two flow conditions, are analyzed. Recess friction, pressure-ram effects at discontinuities in the flow region, and film entrance pressure loss effects are calculated. Entrance pressure loss coefficients over a forward-facing step are presented as functions of the mean flow Reynolds number for pure-pressure and shear-induced laminar flows.  相似文献   
90.
Obesity is often associated with an impairment of the hypothalamic-pituitary-gonadal axis. The leptin-deficient ob/ob mouse model is characterized by a morbid obesity with a sterility in males and females that is corrected by continuous leptin treatment. Since ob/ob mice are maintained on the C57BL/6J inbred genetic background, we sought to determine whether their infertility can be corrected without leptin treatment but via the effect of modifier genes brought into the obese-sterile phenotype by a different genetic background. Thus, we generated via an F2 intercross ob/ob mice on a mixed C57BL/6J-BALB/cJ genetic background and assayed them for fertility by mating with wild-type C57BL/6J mice. Whereas genetically heterogeneous F2 obese females remained sterile like male and female C57BL/6J ob/ob mice, 41% of F2 C57BL/6J-BALB/cJ obese males were capable of reproducing despite a morbidly obese state. Therefore, the sterility of the original C57BL/6J ob/ob mouse model was genetically corrected independently of its obese state via the effects of modifier genes. Unlike testosterone levels, triglyceride levels, and testes weight-to-body weight ratios, which were all higher in fertile vs. sterile mice, glucose levels were similar in both groups, indicating that the underlying hyperglycemia of ob/ob mice was not an impediment to the onset of fertility. A genome-wide scan in F2 ob/ob males resulted in the localization of four modifier loci on chromosomes 1, 3, 5, and 14 with respective quantitative traits consisting of number of pregnancies, testes weights normalized to body weights, body weight at 8 weeks of age, and circulating testosterone. We conclude that the inheritance of modifier genes at the identified loci acts to promote fertility of otherwise sterile leptin-deficient obese male mice.  相似文献   
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