Trade-off between resolution and interactivity in spatial taskperformance

Virtual reality displays usually lag far behind classical computer graphics displays in static image quality parameters, such as resolution. Both the popular press and scientific papers often stress that resolution will have to increase greatly before users can experience virtual environments as “the real thing”. Nevertheless, it is already possible to do some useful work in VR environments. The point we experimentally demonstrate here is that resolution is much less important for interactive tasks that employ immersive VR, where users can explore the environment by moving their heads and bodies, than it is in classical computer graphics applications, where users can only explore by gazing at a single picture. In the context of unmanned aerial vehicles, frame rate (read: passive camera movement) is more important than resolution for target detection, recognition, designation, and tracking. In the experiments reported here, we investigated the relative importance of various image parameters like spatial resolution (number of pixels per video frame), intensity resolution (number of gray levels per pixel), and temporal resolution (number of frame updates per second). Most experimental data concerning these resolutions come from classical psychophysics. However, experimental conditions in classical psychophysics feature stationary observers looking at short-term, pointlike flashes on stationary displays, and are thus far more representative of human interaction with pictures and photographs than with highly interactive systems like those employed in virtual reality     

Drug Release from Lipogels According to Gelling Conditions and Mechanical Treatment

The release rate of a drug dissolved in the liquid phase of lipogels may be greatly affected by the type and concentration of gelling agent and by processing conditions and mechanical treatment of the ointment. These differences in release rate are reduced after application of mechanical stress comparable with the strain exerted on the ointment during application to the skin. Therefore, changes in the concentration of gelling agents used to achieve suitable consistency and manufacturing and packing processes that meet industrial and marketing requirements do not appear to exert a practical influence on drug availability after application to the skin.     

Selectivity of LG50643 for postjunctional muscarinic-receptor subtype in the guinea-pig trachea

The effects of (+/-)-LG50643, a new N-quaternary tropinic ester of phenylcyclohexene carboxylic acid, endowed with a potent antimuscarinic activity, have been investigated on muscarinic receptor-mediated responses of the guinea-pig trachea to electrical field stimulation. An isolated preparation which allows the simultaneous measurement of tritiated acetylcholine release (prejunctional effect) and smooth muscle contraction (postjunctional effect) was used. The guinea-pig epithelium-deprived trachea was stimulated with 500 pulses (20 Hz, 1 ms, 9 V for 5 s, 30 s apart) in the presence of indomethacin (1 microM). Three successive pre- and postjunctional responses were observed. The potencies (-logEC50) of (+/-)-LG50643 for pre- and postjunctional muscarinic receptors were determined and compared with those of selective muscarinic antagonists. In addition, the affinity values of (+/-)-LG50643 for muscarinic-receptor subtypes were determined in radioligand binding experiments in cerebral cortex, heart and salivary glands of rat as target tissues for M1, M2 and M3 receptors, respectively. The results obtained in both functional and binding assays indicate (+/-)-LG50643 is a potent and selective antagonist for the M3-receptor subtype.     

MODELING the VIBRATIONAL RESPONSE of PLANTAIN FRUITS

Plantain fruits of the plantain subgroup ( Musa AAB Group) were obtained at a green stage and used in this study. the fruits were labelled for identification, and stored in a chamber maintained at a temperature of 20C and relative humidity of 90 ± 4%. On daily basis, for a period of 14 days, the fruits were removed from the storage chamber and each was weighed to record the mass. They were vibrated vertically on a vibration exciter through a range of frequencies from 10 to 2000 Hz. the frequency response was modeled by a single-degree-of-freedom Kelvin model. the mass of the fruit, the stiffness, the natural frequency and the critical damping all decreased significantly (p < 0.01) with storage time. There was no significant change (p > 0.05) in the damping coefficient of the fruit. the damping ratio decreased significantly (p < 0.01) with storage time. the models that described the changes in these parameters with storage time were obtained by stepwise regression, and are also presented. It was concluded that a single degree-of-freedom model provides satisfactory results of the vibrational characteristics of intact plantain fruit.     

Promoting the Innovation Activity of SMEs; the Greek Experience

Programmes for stimulating innovation in Small and Medium Enterprise (SMEs) in Greece have been examined. Problems of innovation development, lack of funds, and marketing have been identified. The case is followed by comments from researchers with experience of entrepreneurship in various different countries.     

Maternal complications from tocolytic treatment with beta-mimetics. Three cases of pulmonary edema

We report three cases of pulmonary edema associated with prolonged intravenous tocolytic therapy with beta 2-adrenergic agonists among patients with multiple pregnancies. Although beta 2-adrenergic agonists may have direct myocardial side-effects, the underlying pathophysiologic mechanisms are mainly noncardiogenic. The most important one appears to be the fluid overload, related to amounts of fluids given intravenously and to direct result of beta-sympathomimetic therapy on renal excretion of sodium and water. Neonatal benefit of prolonged tocolytic therapy remains hypothetical. If this strategy is used, the prevention of cardiovascular adverse effects requires an intensive maternal supervision, especially in case of multiple pregnancy, the use of beta 2-adrenergic agonists in concentrated solution in order to reduce the amounts of fluids given intravenously, and the association with progesterone therapy which can reduce the infusion rate and the duration of tocolytic therapy.