不同化工过程本质安全评价方法的比较与分析

给予众多的本质安全评价方法合理的归类,将其分为指标型、模糊理论型、图示型3类.其中,从覆盖范围的角度把指标型方法分为S(safe),SE(safe,environment),SEH(safe,envitronment and health)3种.其次,阐述方法所含有的参数及最终指标的计算方法.再次,对3类评价方法进行评价思路、易用性和结果灵敏性的比较.阐述评价方法改进的方向及内涵,从中找到方法中存在的4个主要问题:(1)指标取值的主观性;(2)使用的数学函数为阶梯函数:(3)评价参数及领域不全面;(4)评价过程逻辑性不强.最后得出本质安全评价方法的3个发展方向:覆盖范围的综合性、评价过程的逻辑性、指标取值的客观性.     

Generation of time delays: simplified models of intracellular signalling in cerebellar Purkinje cells

In many neuronal systems, information is encoded in temporal spike patterns. The recognition and storage of temporal patterns requires the generation and modulation of time delays between inputs and outputs. In cerebellar Purkinje cells, stimulation of metabotropic glutamate receptors (mGluRs) results in a delayed calcium and voltage response that has been implicated in classical conditioning and temporal pattern recognition. Here, we analyse and simplify a complex model of the intracellular signalling network that has been proposed as a substrate for this delayed response. We systematically simplify the original model, present a minimal model of time delay generation, and show that a delayed response can be produced by the combination of negative feedback and autocatalysis, without any intervening signalling steps that would contribute additive delays. The minimal model is analysed using phase plane methods, and classified as an excitable system. We discuss the implication of excitability for computations performed by intracellular signalling networks in general.     

Acoustic emission source characterization in concrete under biaxial loading

The results are reported of a mode identification study on cracks produced during mixed mode loading of concrete. The locations of cracks were found to agree very well with the surface crack patterns for a variety of loading paths. The classification of cracks into mode I and mode II were conducted using a simplified moment tensor analysis. The results indicated that, in general, cracking occurs in mode I, even when the loading is pure shear. Mode II deformations generally follow the mode I cracks, as the crack interface is subjected to shear.     

Cross-national differences in individual knowledge-seeking patterns: a climato-economic contextualization

Electronic Knowledge Repository (EKR) is one of the most commonly deployed knowledge management technologies, yet its success hinges upon employees’ continued use and is further complicated in today’s multinational context. We integrate multiple theoretical linkages into a research model, conceptualizing knowledge-seeking as an instrumental behavior, adopting the technology acceptance model to characterize the individual-level continued EKR knowledge-seeking behavioral model, and drawing on the climato-economic theory to explain cross-national behavioral differences. Using hierarchical linear modeling (HLM), we test the model with data from 1352 randomly sampled knowledge workers across 30 nations. We find that two national-level factors, climate harshness and national wealth, interactively moderate the individual-level relationship between perceived usefulness (PU) and behavioral intention (BI) to continue seeking knowledge from EKR, such that the difference in the strength of this relationship is larger between poor-harsh and poor-temperate nations than between rich-harsh and rich-temperate nations. We find similar cross-level cross-national differences for the link between perceived ease of use (PEOU) and PU but not for the link between PEOU and BI. Implications for research and practice are discussed.     

The Transmogrifier-2: a 1 million gate rapid-prototyping system

This paper describes the Transmogrifier-2 (TM-2), a second-generation multifield programmable gate array (FPGA) rapid-prototyping system. The largest version of the system will comprise 16 boards that each contain two Altera 10K50 FPGA's, four I-Cube interconnect chips, and up to 8 Mbytes of memory. The inter-FPGA routing architecture of the TM-2 uses a novel interconnect structure, a nonuniform partial crossbar, that provides a constant delay between any two FPGA's in the system. The TM-2 architecture is modular and scalable, meaning that systems of various sizes can be constructed from copies of the same board, while maintaining routability and the constant delay feature. Other features include a system-level programmable clock that allows single-cycle access to off-chip memory, and programmable clock waveforms with edge resolution of 10 ns. The first Transmogrifier-2 boards have been manufactured and are functional. They have recently been used successfully in some simple graphics acceleration applications     

Reconciliation of a quantum-distributed Gaussian key

Two parties, Alice and Bob, wish to distill a binary secret key out of a list of correlated variables that they share after running a quantum key distribution (QKD) protocol based on continuous-spectrum quantum carriers. We present a novel construction that allows the legitimate parties to get equal bit strings out of correlated variables by using a classical channel, with as little leaked information as possible. This opens the way to securely correcting nonbinary key elements. In particular, the construction is refined to the case of Gaussian variables as it applies directly to recent continuous-variable protocols for QKD.     

A Voltage and Frequency Droop Control Method for Parallel Inverters

In this paper, a new control method for the parallel operation of inverters operating in an island grid or connected to an infinite bus is described. Frequency and voltage control, including mitigation of voltage harmonics, are achieved without the need for any common control circuitry or communication between inverters. Each inverter supplies a current that is the result of the voltage difference between a reference ac voltage source and the grid voltage across a virtual complex impedance. The reference ac voltage source is synchronized with the grid, with a phase shift, depending on the difference between rated and actual grid frequency. A detailed analysis shows that this approach has a superior behavior compared to existing methods, regarding the mitigation of voltage harmonics, short-circuit behavior and the effectiveness of the frequency and voltage control, as it takes the R to X line impedance ratio into account. Experiments show the behavior of the method for an inverter feeding a highly nonlinear load and during the connection of two parallel inverters in operation.     

Incremental value of prognostic testing in patients with known or suspected ischemic heart disease: a basis for optimal utilization of exercise technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography

OBJECTIVES: This study assessed the incremental prognostic implications of normal and equivocal exercise technetium-99m (Tc-99m) sestamibi single-photon emission computed tomography (SPECT) and sought to determine its incremental prognostic value, impact on patient management and cost implications. BACKGROUND: The prognostic implications of Tc-99m sestamibi SPECT are not well defined, and risk stratification using this test has not been explored. METHODS: We studied 1,702 patients referred for exercise Tc-99m sestamibi SPECT who were followed up for a mean (+/- SD) of 20 +/- 5 months. Patients with previous percutaneous transluminal coronary angioplasty or coronary artery bypass surgery were excluded. The SPECT studies were assessed using semiquantitative visual analysis. Cardiac death and myocardial infarction were considered "hard" events, and coronary angioplasty and bypass surgery > 60 days after testing were considered "soft" events. RESULTS: Of the 1,702 patients studied, 1,131 had normal or equivocal scan results. A total of 10 events occurred in this group (1 cardiac death and 1 myocardial infarction [0.2% hard events]; 4 coronary angioplasty and 4 bypass surgery procedures [0.7% soft events]). The rates of hard events and referral to catheterization after SPECT were similarly low in patients with a low (< 0.15), intermediate (0.15 to 0.85) and high (> 0.85) post-exercise treadmill test (ETT) likelihood of coronary artery disease. With respect to scan type, patients with normal, probably normal or equivocal scan results had similarly low hard event rates. In the 571 patients with abnormal scan results, there were 43 hard events (7.5%) and 42 soft events (7.4%) (p < 0.001 vs. 1,131 patients with normal scan results for both). When the complete spectrum of scan responses was considered, SPECT provided incremental prognostic value in all patient subgroups analyzed. However, the nuclear scan was cost-effective only in patients with interpretable exercise ECG responses and an intermediate to high post-ETT likelihood of coronary artery disease and in those with uninterpretable exercise ECG responses and an intermediate to high pre-ETT likelihood of coronary artery disease. CONCLUSIONS: Normal or equivocal exercise Tc-99m sestamibi study results are associated with a benign prognosis, even in patients with a high likelihood of coronary artery disease. Although incremental prognostic value is added by nuclear testing in all patient subgroups, a testing strategy incorporating nuclear testing proved to be cost-effective only in the groups with an intermediate to high likelihood of coronary artery disease before scanning.