Stress Corrosion Cracking and Oil Leakage in a Control Oil Piping System

This article describes the results of an investigation concerning with the failure of a pipe which was carrying oil from the control oil unit to the steam turbine control valves servomotor. The failure was in the form of a crack, propagating horizontally along the pipe. The crack initiated on the outside of the pipe. The cause of the failure was investigated by conducting visual examination, detailed macro and microstructural examinations and determining the composition of material from the failed pipe. The composition of the pipe material was analyzed by atomic absorption spectrometer. The failure of the oil pipe was attributed to stress corrosion cracking. The pipe material is A312 TP 304L. Recommendation to minimize such failures includes coating the pipe to prevent contact with chloride from the surrounding marine environment.     

Fabrication of innovative charkha for pashmina spinning and its impact assessment

Pashmina, a finest natural animal fiber is utilized for preparation of world famous Kashmiri pashmina shawls by traditional practices. Hand spinning is one of the important processing step, wherein fibers are converted into a fine yarn on a traditional spinning wheel (yander). The task is usually carried out by women folk. It is a laborious process resulting in a lot of physical stress affecting the efficiency of artisans. An innovative charkha has been fabricated to reduce the physical stress and its effect on the spinning efficiency and remuneration of artisans over traditional one was evaluated. The study revealed that innovative charkha was efficient in terms of time consumed for spinning by 73.50% over traditional one besides decreasing physical drudgery. In terms of income, there was an increase of 146% over traditional one for same period of time without deteriorating the quality of yarn.     

Determining SPICE parameter values for BJTs

The roles of hybrid-π, two-port, and SPICE transistor parameter are compared. A step-by-step procedure is described for determining numerical parameter values for a dynamic SPICE model of a bipolar junction from transistor manufacturer's measured data. The procedure is illustrated with an example     

Application of selftuning regulator algorithm to generating unit controllers

The processing capability of computers makes it feasible to implement sophisticated techniques for process control. However, to minimize the software development costs, it is desirable to develop algorithms that can have a wider application. In keeping with this, an AVR and speed governor for a generating unit have been designed using the same algorithm, called the selftuning regulator. The selftuning AVR and speed governor have been implemented using a microprocessor and a minicomputer online. The feasibility of developing unified algorithms is demonstrated by means of realtime tests, in which the two controllers are used simultaneously for a generating unit physical model.     

Results of test on microprocessor-based voltage and speed regulators carried out on a large physical model complex

Results of experimental tests carried out with microprocessor-based voltage and speed regulators using a digital-analogue-physical model complex of a large power system at the Siberian Power Institute of the USSR Academy of Sciences are described. The physical test facility, and the test objectives and procedures are also outlined. Tests were carried out on a Soviet-built microprocessor AVR and a Canadian-built microprocessor AVR and speed governor. The work described shows that the development of speed and voltage regulators using microprocessors is a feasible and promising proposition.     

Generalized neuron-based PSS and adaptive PSS

Artificial neural networks can be used as intelligent controllers to control non-linear, dynamic systems through learning, which can easily accommodate the non-linearities and time dependencies. However, they require large training time and large number of neurons to deal with complex problems. Taking benefit of the characteristics of a Generalized Neuron that requires much smaller training data and shorter training time, a Generalized Neuron-Based Power System Stabilizer (GNPSS) and an adaptive version of the same have been developed. The objective of this paper is to compare the performance of the GNPSS with that of an adaptive version, the weights of which are updated on-line.     

Cytotoxicity of curcuminoids and some novel compounds from Curcuma zedoaria

Bioassay-directed fractionation of an EtOH extract of Curcuma zedoaria led to isolation of an active curcuminoid, which was identified as demethoxycurcumin (2) by comparison of its 1H and 13C NMR spectra with literature data and by direct comparison with synthetic material. Curcumin (1) and bisdemethoxycurcumin (3) were also obtained. Curcuminoids (1-3) were synthesized and demonstrated to be cytotoxic against human ovarian cancer OVCAR-3 cells. The observed CD50 values of 1, 2, and 3 were 4.4, 3.8, and 3.1 microg/mL, respectively. Three additional novel compounds, 3, 7-dimethylindan-5-carboxylic acid (4), curcolonol (5), and guaidiol (6), were also isolated from the EtOH extract. The structures and relative stereochemistry of 4-6 were determined by spectroscopic methods and X-ray crystallographic analysis.     

Examination of the kinetics of herpes simplex virus glycoprotein D binding to the herpesvirus entry mediator, using surface plasmon resonance

Previously, we showed that truncated soluble forms of herpes simplex virus (HSV) glycoprotein D (gDt) bound directly to a truncated soluble form of the herpesvirus entry mediator (HveAt, formerly HVEMt), a cellular receptor for HSV. The purpose of the present study was to determine the affinity of gDt for HveAt by surface plasmon resonance and to compare and contrast the kinetics of an expanded panel of gDt variants in binding to HveAt in an effort to better understand the mechanism of receptor binding and virus entry. Both HveAt and gDt are dimers in solution and interact with a 2:1 stoichiometry. With HveAt, gD1(306t) (from the KOS strain of HSV-1) had a dissociation constant (KD) of 3.2 x 10(-6) M and gD2(306t) had a KD of 1.5 x 10(-6) M. The interaction between gDt and HveAt fits a 1:1 Langmuir binding model, i.e., two dimers of HveAt may act as one binding unit to interact with one dimer of gDt as the second binding unit. A gD variant lacking all signals for N-linked oligosaccharides had an affinity for HveAt similar to that of gD1(306t). A variant lacking the bond from cysteine 1 to cysteine 5 had an affinity for HveAt that did not differ from that of the wild type. However, variants with double cysteine mutations that eliminated either of the other two disulfide bonds showed decreased affinity for HveAt. This result suggests that two of the three disulfide bonds of gD are important for receptor binding. Four nonfunctional gDt variants, each representing one functional domain of gD, were also studied. Mutations in functional regions I and II drastically decreased the affinity of gDt for HveAt. Surprisingly, a variant with an insertion in functional region III had a wild-type level of affinity for HveAt, suggesting that this domain may function in virus entry at a step other than receptor binding. A variant with a deletion in functional region IV [gD1(Delta290-299t)] exhibited a 100-fold enhancement in affinity for HveAt (KD = 3.3 x 10(-8) M) due mainly to a 40-fold increase in its kinetic on rate. This agrees with the results of other studies showing the enhanced ability of gD1(Delta290-299t) to block infection. Interestingly, all the variants with decreased affinities for HveAt exhibited decreased kinetic on rates but only minor changes in their kinetic off rates. The results suggest that once the complex between gDt and HveAt forms, its stability is unaffected by a variety of changes in gD.