Temperature measurement in fire test furnaces

A study of errors associated with temperature measurement in fire endurance test furnaces has shown that conventionally used thermocouples are subject to large time constant errors in the first 20 minutes of a standard test.     

Effect of dietary zinc levels on health and productivity of gilts and sows through two parities

The influence of 0, 50, 500 or 5,000 ppm supplemental Zn on productive characteristics, weight change, and serum and organ mineral concentrations of 60 crossbred and purebred Yorkshire gilts was evaluated. Gilts were fed their respective treatment from 30 kg body weight until the completion of two parities. Sows fed 5,000 ppm supplemental Zn weighed significantly less than sows from the other treatments when killed. Serum alkaline phosphatase activity was higher for the sows fed the highest level of Zn in all replications at 10 and 14 mo of age than for sows from the other treatments. Sows fed 0, 50 or 500 ppm had lower serum Zn and higher serum Cu concentrations than sows fed 5,000 ppm Zn at 10 and 14 mo of age. The number of pigs farrowed (total and live) and birth weight were not affected by dam's dietary treatment. However, sows receiving no additional Zn had a higher number of abnormal pigs/litter than sows on the other treatments. Sows fed 5,000 ppm additional Zn weaned fewer pigs that weighed less at weaning than sows on the other treatments. The concentration of Zn in the sow's liver increased significantly and liver Cu decreased as dietary level of Zn increased. Sows receiving 5,000 ppm Zn had lower hepatic Fe stores compared with sows receiving 500 ppm Zn. Elevated renal Cu and Zn concentrations were found in sows fed the highest level of Zn supplementation. The Zn concentration was higher and the Cu concentration lower in the aorta of sows fed 5,000 ppm Zn compared with sows fed 0 or 50 ppm additional Zn. Incidence of osteochondrosis was higher in sows supplemented with 5,000 ppm Zn than for sows from the other treatments.     

Analysis of a modified variable-length tuning post in a rectangular waveguide.

A modified variable-length post for use in high power waveguide tuning networks is analyzed to determine its reactance properties. Theoretical predictions are shown to be in good agreement with experimental results. An investigation of the reactance characteristics and the aperture voltage characteristics of the modified post, as a function of its dimensions, is also reported.     

Transient response improvement of feedback control systems using hybrid reference control

By means of the internal model principle, an approach to improve the performance of a stabilised closed-loop continuous time linear system based on manipulation of the reference signal is developed. A change in the reference signal is equivalent to implementing an instantaneous change via the choice of a decision vector in the state of the reference signal model, and the analysis of the proposed approach called hybrid reference control (HRC) system is then shown to be equivalent to the analysis of a linear impulsive dynamical system. Conditions for asymptotic stability and convergence of the output tracking error for a HRC system are expressed in term of conditions on the decision vectors. Conditions are then derived which guarantee that the HRC system leads to an improved transient performance compared to a conventional closed-loop control system. In particular, it is shown how decision vectors are chosen so that a HRC system results in a deadbeat response.     

An adaptive IIR filter algorithm based on observers

The output error approach to adaptive IIR filtering is considered from a state observation perspective, and a new algorithm, termed the observer-based regressor filtering (OBRF) algorithm, is developed. The convergence requirements of the OBRF are established as a persistent excitation condition on the regressor and a strict positive reality (SPR) condition on an operator arising in the algorithm. Speed of convergence experiments show that the OBRF algorithm converges more quickly than the related output error algorithm for the hyperstable adaptive recursive filter (HARF), although the OBRF algorithm converges as quickly as typical equation error schemes. The OBRF is shown to compare favorably with equation error with respect to parameter bias in the presence of output measurement noise. Thus, OBRF is a compromise between the equation error and output error approaches. In addition, algorithm parameter selection to satisfy the SPR condition for OBRF is explored and compared with the related conditions for HARF     

Proinflammatory macrophage-activating properties of the novel phospholipid diacylglycerol pyrophosphate

We have found that the novel phospholipid diacylglycerol pyrophosphate (DGPP), identified in bacteria, yeast, and plants, but not in mammalian cells, is able to potently activate macrophages for enhanced secretion of arachidonate metabolites, a key event in the immunoinflammatory response of leukocytes. Macrophage responses to DGPP are specific and are not mediated by its conversion into other putative lipid mediators such as phosphatidic acid, lysophosphatidic acid, or diacylglycerol. The responses to DGPP are compatible with a receptor-recognition event because they are blocked by suramin. Intracellular signaling initiated by DGPP includes phosphorylation and activation of the Group IV cytosolic phospholipase A2 and of the extracellular-signal regulated p42 mitogen-activated protein kinase (MAPK) and p44 MAPK, and membrane translocation of the protein kinase C isoenzymes alpha, epsilon, delta. These results establish DGPP as a novel macrophage-activating factor and suggest a potential role for this compound in triggering homeostatic cellular responses.     

Substrate phosphorylation in the protein kinase Cgamma knockout mouse

The phosphorylation state of three identified neural-specific protein kinase C substrates (RC3, GAP-43/B-50, and MARCKS) was monitored in hippocampal slices of mice lacking the gamma-subtype of protein kinase C and wild-type controls by quantitative immunoprecipitation following 32Pi labeling. Depolarization with potassium, activation of glutamate receptors with glutamate, or direct stimulation of protein kinase C with a phorbol ester increased RC3 phosphorylation in wild-type animals but failed to affect RC3 phosphorylation in mice lacking the gamma-subtype of protein kinase C. Our results suggests the following biochemical pathway: activation of a postsynaptic (metabotropic) glutamate receptor stimulates the gamma-subtype of protein kinase C, which in turn phosphorylates RC3. The inability to increase RC3 phosphorylation in mice lacking the gamma-subtype of protein kinase C by membrane depolarization or glutamate receptor activation may contribute to the spatial learning deficits and impaired hippocampal LTP observed in these mice.     

Increased collateral blood flow to ischemic myocardium by estrogen replacement therapy may contribute to reduced incidence of fatal and non-fatal acute myocardial infarction in postmenopausal women

We report a case of neurosarcoidosis, which simulated a cerebral tumor located at the floor of the III ventricle, associated to an aseptic meningitis and diabetes insipidus. It was the first and only manifestation of the illness. The response to steroid therapy was very favourable, with complete clinical recuperation and radiological resolution.