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81.
The shapes of our cities change very frequently. These changes have to be reflected in data sets representing urban objects. However, it must be assured that frequent updates do not affect geometric-topological consistency. This important aspect of spatial data quality guarantees essential assumptions on which users and applications of 3D city models rely: viz. that objects do not intersect, overlap or penetrate mutually, or completely cover one another. This raises the question how to guarantee that geometric-topological consistency is preserved when data sets are updated. Hence, there is a certain risk that plans and decisions which are based on these data sets are erroneous and that the tremendous efforts spent for data acquisition and updates become vain. In this paper, we solve this problem by presenting efficient transaction rules for updating 3D city models. These rules guarantee that geometric-topological consistency is preserved (Safety) and allow for the generation of arbitrary consistent 3D city models (Completeness). Safety as well as completeness is proven with mathematical rigor, guaranteeing the reliability of our method. Our method is applicable to 3D city models, which define—besides the terrain surface—complex spatial objects like buildings with rooms and storeys as interior structures, as well as bridges and tunnels. Those objects are represented as aggregations of solids, and their surfaces are complex from a topology point of view. 3D GIS models like CityGML, which are widely used to represent cities, provide the means to define semantics, geometry and topology, but do not address the problem of maintaining consistency. Hence, our approach complements CityGML.  相似文献   
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We present a filter-and-refine method to speed up nearest neighbor searches with the Kullback–Leibler divergence for multivariate Gaussians. This combination of features and similarity estimation is of special interest in the field of automatic music recommendation as it is widely used to compute music similarity. However, the non-vectorial features and a non-metric divergence make using it with large corpora difficult, as standard indexing algorithms can not be used. This paper proposes a method for fast nearest neighbor retrieval in large databases which relies on the above approach. In its core the method rescales the divergence and uses a modified FastMap implementation to speed up nearest-neighbor queries. Overall the method accelerates the search for similar music pieces by a factor of 10–30 and yields high recall values of 95–99% compared to a standard linear search.  相似文献   
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Hepatocellular carcinoma (HCC) still remains a difficult to cure malignancy. In recent years, the focus has shifted to lipid metabolism for the treatment of HCC. Very little is known about hepatitis B virus (HBV) and C virus (HCV)-related hepatic lipid disturbances in non-malignant and cancer tissues. The present study showed that triacylglycerol and cholesterol concentrations were similar in tumor adjacent HBV and HCV liver, and were not induced in the HCC tissues. Higher levels of free cholesterol, polyunsaturated phospholipids and diacylglycerol species were noted in non-tumorous HBV compared to HCV liver. Moreover, polyunsaturated phospholipids and diacylglycerols, and ceramides declined in tumors of HBV infected patients. All of these lipids remained unchanged in HCV-related HCC. In HCV tumors, polyunsaturated phosphatidylinositol levels were even induced. There were no associations of these lipid classes in non-tumor tissues with hepatic inflammation and fibrosis scores. Moreover, these lipids did not correlate with tumor grade or T-stage in HCC tissues. Lipid reprogramming of the three analysed HBV/HCV related tumors mostly resembled HBV-HCC. Indeed, lipid composition of non-tumorous HCV tissue, HCV tumors, HBV tumors and HBV/HCV tumors was highly similar. The tumor suppressor protein p53 regulates lipid metabolism. The p53 and p53S392 protein levels were induced in the tumors of HBV, HCV and double infected patients, and this was significant in HBV infection. Negative correlation of tumor p53 protein with free cholesterol indicates a role of p53 in cholesterol metabolism. In summary, the current study suggests that therapeutic strategies to target lipid metabolism in chronic viral hepatitis and associated cancers have to consider disease etiology.  相似文献   
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Carbonates are a class of compounds that have recently found increasing interest in commercial applications owing to their physical properties and relatively straightforward synthesis. In this work, physical and fuel properties of five straight-chain C17–39 and three branched C17–33 oleochemical carbonates were investigated. These properties included cetane number (CN), low-temperature properties, (kinematic) viscosity, lubricity, and surface tension. The carbonates studied had CN ranging from 47 to 107 depending on carbon chain length and branching. For the same number of carbons, the CN of carbonates were lower than those of FA alkyl esters owing to interruption of the CH2 chain by the carbonate moiety. Kinematic viscosities at 40°C ranged from 4.9 to 22.6 mm2/s whereas m.p. ranged from +3 to below −50°C depending on the carbonate structure. High-frequency reciprocating rig testing showed the neat carbonates to have acceptable lubricity that improved as chain length increased. Finally, the carbonate's ability to influence cold-flow properties in biodiesel (methyl soyate) and lubricity in low-lubricity ultra-low sulfur diesel were examined. The carbonates studied did not significantly affect cold flow or lubricity properties at concentrations up to 10,000 ppm (1 wt%). The properties of the carbonates resemble those of fatty alkyl esters with similar trends resulting from compound structure.  相似文献   
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Studies of the microstructure of porous solids by physisorption measurements . The principal experimental methods for studying the microstructure of porous solids are based on physisorption measurements. The resulting sorption isotherms can yield data such as surface area and pore radius distribution, which are of great importance for development and characterization of porous catalysts. After a brief presentation of available measuring equipment, the main concern of this survey is the evaluation of sorption isotherms. In particular, methods for determining the micropore contribution to the total pore volume and the pore radius distribution in the micropore range are examined critically with regard to their reliability.  相似文献   
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