Erratum to: Anionic liposomes for small interfering ribonucleic acid (siRNA) delivery to primary neuronal cells: Evaluation of alpha-synuclein knockdown efficacy

Nano Research - The name of the fourth author in the original version of this article was unfortunately wrongly written on the first page. Instead of Caitriona M. O’iscoll It should read...     

Test results of a medium temperature solar engine

The results of a test programme of a completely fluorinated organic fluid solar engine at fluid temperatures around 250°C are Engine design characteristics. as deduced using the particular fluid properties are briefly described problems encountered in the preliminary test phase and relating to fluid losses, heat exchangers reduced performance and minor mechanical disturbances are illustrated together with the actions undertaken to improve the original engine behaviour. Detailed engine overall and components performance, as derived from a series of tests, carried out with a fuel fired heat source (simulating the actual solar heating loop) are presented. Engine efficiency, with reference to the net power output at the high speed shaft proved to be around 21%, at 250°C turbine inlet temperature which can be compared with 22.6% design value at the same temperature and with 23.6% original goal at 280°C top cycle temperature. The analysis of the heat transfer coefficients within the various heat exchangers support the suspicion that available information on working fluid transport properties is not sufficiently accurate.     

Study of the Expression and Function of Calcium-Sensing Receptor in Human Skeletal Muscle

Skeletal muscle has an outstanding capacity for regeneration in response to injuries, but there are disorders in which this process is seriously impaired, such as sarcopenia. Pharmacological treatments to restore muscle trophism are not available, therefore, the identification of suitable therapeutic targets that could be useful for the treatment of skeletal reduced myogenesis is highly desirable. In this in vitro study, we explored the expression and function of the calcium-sensing receptor (CaSR) in human skeletal muscle tissues and their derived satellite cells. The results obtained from analyses with various techniques of gene and protein CaSR expression and of its secondary messengers in response to calcium (Ca²⁺) and CaSR drugs have demonstrated that this receptor is not present in human skeletal muscle tissues, neither in the established satellite cells, nor during in vitro myogenic differentiation. Taken together, our data suggest that, although CaSR is a very important drug target in physiology and pathology, this receptor probably does not have any physiological role in skeletal muscle in normal conditions.