Magnetic Resonance Imaging Correlates of White Matter Gliosis and Injury in Preterm Fetal Sheep Exposed to Progressive Systemic Inflammation

Progressive fetal infection/inflammation is strongly associated with neural injury after preterm birth. We aimed to test the hypotheses that progressively developing fetal inflammation leads to neuroinflammation and impaired white matter development and that the histopathological changes can be detected using high-field diffusion tensor magnetic resonance imaging (MRI). Chronically instrumented preterm fetal sheep at 0.7 of gestation were randomly assigned to receive intravenous saline (control; n = 6) or a progressive infusion of lipopolysaccharide (LPS, 200 ng intravenous over 24 h then doubled every 24 h for 5 days to induce fetal inflammation, n = 7). Sheep were killed 10 days after starting the infusions, for histology and high-field diffusion tensor MRI. Progressive LPS infusion was associated with increased circulating interleukin (IL)-6 concentrations and moderate increases in carotid artery perfusion and the frequency of electroencephalogram (EEG) activity (p < 0.05 vs. control). In the periventricular white matter, fractional anisotropy (FA) was increased, and orientation dispersion index (ODI) was reduced (p < 0.05 vs. control for both). Histologically, in the same brain region, LPS infusion increased microglial activation and astrocyte numbers and reduced the total number of oligodendrocytes with no change in myelination or numbers of immature/mature oligodendrocytes. Numbers of astrocytes in the periventricular white matter were correlated with increased FA and reduced ODI signal intensities. Astrocyte coherence was associated with increased FA. Moderate astrogliosis, but not loss of total oligodendrocytes, after progressive fetal inflammation can be detected with high-field diffusion tensor MRI.     

The influence of performance standards and feedback on speed and accuracy in an electronically monitored data‐entry task

This study examined performance effects of using electronic performance monitoring (EPM) and feedback to induce compliance with speed and accuracy standards in a data entry task. The study focused on subjects who had difficulty meeting a preestablished data entry speed standard. Subjects performed a data‐entry task for 3 days. On the 1st (baseline) day, no performance standards were imposed, and all subjects were instructed to work at their normal speed and accuracy levels. For the 2nd and 3rd days of the experiment, subjects were assigned at random to one of two groups. In an experimental group, EPM and feedback were used to induce compliance with preestablished speed and accuracy standards. In a control group, subjects were unaware of EPM and received no feedback; they were instructed to continue working at their normal speed and accuracy levels. The introduction of EPM work management in the experimental group led to significant increases in data‐entry speed that were accompanied by significant increases in data‐entry errors. In addition, data‐entry errors produced by experimental subjects increased significantly over time during the workdays in which EPM work management was employed. These effects are discussed in terms of relevant research on goal setting and feedback utilization. The results suggest that when performance standards and feedback that emphasize speed more than accuracy are applied in EPM‐managed work settings, speed increments may be offset by decrements in work quality.     

Toward a more complete understanding of the link between multicultural experience and creativity.

Responds to G. J. Rich's comments (see record 2009-01602-011) on the current author's original article (see record 2008-03389-003) which presented evidence supporting the idea that multicultural experience can facilitate creativity. Rich has argued that our review, although timely and important, was somewhat limited in scope, focusing mostly on smaller forms of creativity ("little c": e.g., paper-and-pencil measures of creativity) as well as on larger forms of multicultural experience ("Big M": e.g., living in a foreign country). We agree with many aspects of Rich's assessment. The issue of whether different forms of multicultural experience can affect Big C creativity is of interest to both scholars and laypeople because creative breakthroughs can literally alter the course of human progress. The response to our article, including Rich's reply, supports our view that the interest in multicultural experience and creativity is far from exhausted; future research will certainly uncover important new insights. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social Information-Processing Skills Training to Promote Social Competence and Prevent Aggressive Behavior in the Third Grades.

This article describes a school-based study designed to promote social competence and reduce aggressive behavior by strengthening children's skills in processing social information and regulating emotions. Three successive cohorts of 3rd graders (N = 548) from 2 schools participated. In 2000-2001, children received a routine health curriculum; in 2001-2002, students received the Making Choices: Social Problem Solving Skills for Children (MC) program; and in 2002-2003, children received MC supplemented with teacher and parent activities. Compared with children in the routine condition, children in both MC conditions were rated lower on posttest social and overt aggression and higher on social competence. Moreover, they scored significantly higher on an information-processing skills posttest. The findings suggest that prevention programs can strengthen social- emotional skills and produce changes in aggressive behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

For God (or) country: The hydraulic relation between government instability and belief in religious sources of control.

It has been recently proposed that people can flexibly rely on sources of control that are both internal and external to the self to satisfy the need to believe that their world is under control (i.e., that events do not unfold randomly or haphazardly). Consistent with this, past research demonstrates that, when personal control is threatened, people defend external systems of control, such as God and government. This theoretical perspective also suggests that belief in God and support for governmental systems, although seemingly disparate, will exhibit a hydraulic relationship with one another. Using both experimental and longitudinal designs in Eastern and Western cultures, the authors demonstrate that experimental manipulations or naturally occurring events (e.g., electoral instability) that lower faith in one of these external systems (e.g., the government) lead to subsequent increases in faith in the other (e.g., God). In addition, mediation and moderation analyses suggest that specific concerns with order and structure underlie these hydraulic effects. Implications for the psychological, sociocultural, and sociopolitical underpinnings of religious faith, as well as system justification theory, are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A spectrometer of polarized neutrons

A polarized neutron spectrometer intended for studies of interactions of nuclei and condensed matter with polarized neutrons with energies in the range from thermal energies to several electron volts was designed at the IBR-2 pulsed reactor (JINR, Dubna). Diffraction on magnetized Co(92%)–Fe(8%) single crystals was used to polarize neutrons and analyze the polarization. The attained neutron polarization was ∼95% within the entire energy range.     

Multicultural experience enhances creativity: The when and how.

Many practices aimed at cultivating multicultural competence in educational and organizational settings (e.g., exchange programs, diversity education in college, diversity management at work) assume that multicultural experience fosters creativity. In line with this assumption, the research reported in this article is the first to empirically demonstrate that exposure to multiple cultures in and of itself can enhance creativity. Overall, the authors found that extensiveness of multicultural experiences was positively related to both creative performance (insight learning, remote association, and idea generation) and creativity-supporting cognitive processes (retrieval of unconventional knowledge, recruitment of ideas from unfamiliar cultures for creative idea expansion). Furthermore, their studies showed that the serendipitous creative benefits resulting from multicultural experiences may depend on the extent to which individuals open themselves to foreign cultures, and that creativity is facilitated in contexts that deemphasize the need for firm answers or existential concerns. The authors discuss the implications of their findings for promoting creativity in increasingly global learning and work environments. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

From self-prediction to self-defeat: Behavioral forecasting, self-fulfilling prophecies, and the effect of competitive expectations.

Four studies explored behavioral forecasting and the effect of competitive expectations in the context of negotiations. Study 1 examined negotiators' forecasts of how they would behave when faced with a very competitive versus a less competitive opponent and found that negotiators believed they would become more competitive. Studies 2 and 3 examined actual behaviors during a negotiation and found that negotiators who expected a very competitive opponent actually became less competitive, as evidenced by setting lower, less aggressive reservation prices, making less demanding counteroffers, and ultimately agreeing to lower negotiated outcomes. Finally, Study 4 provided a direct test of the disconnection between negotiators' forecasts for their behavior and their actual behaviors within the same sample and found systematic errors in behavioral forecasting as well as evidence for the self-fulfilling effects of possessing a competitive expectation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)