A rationale for the TEI recommendations for feature-structure markup

In this paper, we concentrate on justifying the decisions we made in developing the TEI recommendations for feature structure markup. The first four sections of this paper present the justification for the recommended treatment of feature structures, of features and their values, and of combinations of features or values and of alternations and negations of features and their values. Section 5 departs briefly from the linguistic focus to argue that the markup scheme developed for feature structures is in fact a general-purpose mechanism that can be used for a wide range of applications. Section 6 describes an auxiliary document called a feature system declaration that is used to document and validate a system of feature-structure markup. The seventh and final section illustrates the use of the recommended markup scheme with two examples, lexical tagging and interlinear text analysis.Terry Langendoen is Professor and Head of the Department of Linguistics at The University of Arizona. He was Chair of the TEI Committee on Analysis and Interpretation. He received his PhD in Linguistics from the Massachusetts Institute of Technology in 1964, and held teaching positions at The Ohio State University and the City University of New York (Brooklyn College and the Graduate Center) before moving to Arizona in 1988. He is author, co-author, or co-editor of six books in linguistics, and of numerous articles.Gary Simons is Director of the Academic Computing Department of the Summer Institute of Linguistics, Dallas, TX. He served on the TEI Committee on Analysis and Interpretation. He received his PhD in Linguistics (with minor emphasis in Computer Science) from Cornell University in 1979. Before taking up his current position in 1984, he spent five years in the Solomon Islands doing field work with SIL. He is author, co-author, or co-editor of eight books in the fields of linguistics and linguistic computing.The initial feature-structure recommendations were formulated by the Analysis and Interpretation Committee at a meeting in Tucson, Arizona in March 1990, following suggestions by Mitch Marcus and Beatrice Santorini. The authors received valuable help in the further revision and refinement of the recommendations from Steven Zepp.     

Noble Metal Ion-Directed Assembly of 2D Materials for Heterostructured Catalysts and Metallic Micro-Texturing

Assembling 2D-material (2DM) nanosheets into micro- and macro-architectures with augmented functionalities requires effective strategies to overcome nanosheet restacking. Conventional assembly approaches involve external binders and/or functionalization, which inevitably sacrifice 2DM's nanoscale properties. Noble metal ions (NMI) are promising ionic crosslinkers, which can simultaneously assemble 2DM nanosheets and induce synergistic properties. Herein, a collection of NMI–2DM complexes are screened and categorized into two sub-groups. Based on the zeta potentials, two assembly approaches are developed to obtain 1) NMI-crosslinked 2DM hydrogels/aerogels for heterostructured catalysts and 2) NMI–2DM inks for templated synthesis. First, tetraammineplatinum(II) nitrate (TPtN) serves as an efficient ionic crosslinker to agglomerate various 2DM dispersions. By utilizing micro-textured assembly platforms, various TPtN–2DM hydrogels are fabricated in a scalable fashion. Afterward, these hydrogels are lyophilized and thermally reduced to synthesize Pt-decorated 2DM aerogels (Pt@2DM). The Pt@2DM heterostructures demonstrate high, substrate-dependent catalytic activities and promote different reaction pathways in the hydrogenation of 3-nitrostyrene. Second, PtCl₄ can be incorporated into 2DM dispersions at high NMI molarities to prepare a series of PtCl₄–2DM inks with high colloidal stability. By adopting the PtCl₄–graphene oxide ink, various Pt micro-structures with replicated topographies are synthesized with accurate control of grain sizes and porosities.     

Exploring age and gender differences of computational thinkers in primary school: A developmental perspective

Over the past decade, the call to foster computational thinking (CT) in every child has received considerable attention. However, there is little understanding of whether children are developmentally ready to think computationally and what specific CT concepts and skills can be developed at various ages. This study explored the developmental and gender differences in CT skills of 197 Grade 4–6 students (aged 9–13) before being exposed to instruction and investigated the age–gender interaction effects on their CT acquisition in an intervention combining both programming and non-programming (unplugged) activities. Results show that students' CT skills followed a developmental progression before instruction. Gender difference across ages was insignificant in conditionals, logical operators, pattern recognition and generalization skills. Additionally, students of different ages developed CT differently during the intervention, and their CT acquisition was unaffected by gender. Implications for practice and research in CT education were discussed.     

Composite bending-dominated hollow nanolattices: A stiff,cyclable mechanical metamaterial

Manufacturing ultralight and mechanical reliable materials has been a long-time challenge. Ceramic-based mechanical metamaterials provide significant opportunities to reverse their brittle nature and unstable mechanical properties and have great potential as strong, ultralight, and ultrastiff materials. However, the failure of ceramics nanolattice and degradation of strength/modulus with decreasing density are caused by buckling of the struts and failure of the nodes within the nanolattices, especially during cyclic loading. Here, we explore a new class of 3D ceramic-based metamaterials with a high strength–density ratio, stiffness, recoverability, cyclability, and optimal scaling factor. Deformation mode of the fabricated nanolattices has been engineered through the unique material design and architecture tailoring. Bending-dominated hollow nanolattice (B-H-Lattice) structure is employed to take advantages of its flexibility, while a few nanometers of carbonized mussel-inspired bio-polymer (C-PDA) is coherently deposited on ceramics’ nanolayer to enable non-buckling struts and bendable nodes during deformation, resulting in reliable mechanical properties and outperforming the current bending-dominated lattices (B-Lattices) and carbon-based cellulose materials. Meanwhile, the structure has comparable stiffness to stretching-dominated lattices (S-Lattices) while with better cyclability and reliability. The B-H-Lattices exhibit high specific stiffness (>10⁶?Pa·kg^?1·m^?3), low-density (～30?kg/m³), buckling-free recovery at 55% strain, and stable cyclic loading behavior under up to 15% strain. As one of the B-Lattices, the modulus scaling factor reaches 1.27, which is lowest among current B-Lattices. This study suggests that non-buckling behavior and reliable nodes are the key factors that contribute to the outstanding mechanical performance of nanolattice materials. A new concept of engineering the internal deformation behavior of mechanical metamaterial is provided to optimize their mechanical properties in real service conditions.     

Situating digital storytelling within African communities

We reflect on the methods, activities and perspectives we used to situate digital storytelling in two rural African communities in South Africa and Kenya. We demonstrate how in-depth ethnography in a village in the Eastern Cape of South Africa and a design workshop involving participants from that village allowed us to design a prototype mobile digital storytelling system suited to the needs of rural, oral users. By leveraging our prototype as a probe and observing villagers using it in two villages in South Africa and Kenya, we uncovered implications for situating digital storytelling within those communities. Finally, we distil observations relevant to localizing storytelling and their implications for transferring design into a different community.     

2,4-Diamino-5-(2'-arylpropargyl)pyrimidine derivatives as new nonclassical antifolates for human dihydrofolate reductase inhibition

Dihydrofolate reductase (DHFR) has been a well-recognized target for the development of therapeutics for human cancers for several decades. Classical inhibitors of DHFR use an active transport mechanism to gain access to the cell; disabling this mechanism creates a pathway for resistance. In response, recent research focuses on nonclassical lipid-soluble DHFR inhibitors that are designed to passively diffuse through the membrane. Here, a new series of propargyl-linked antifolates are investigated as potential nonclassical human DHFR inhibitors. Several of these compounds exhibit potent enzyme inhibition with 50% inhibition concentration values under 500 nM. Molecular docking investigations show that the compounds maintain conserved hydrogen bonds between the pyrimidine ring and the enzyme as well as form van der Waals interactions with critical residues in the active site. Interestingly, the most potent compound, 2,4-diamino-5-(3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (compound 35), is 3500-fold more potent than trimethoprim, a potent inhibitor of bacterial DHFR but weak inhibitor of human DHFR. The two structural differences between compound 35 and trimethoprim show that the propargyl linkage and the substitution at C6 of the pyrimidine ring are critical to the formation of contacts with Thr 56, Ser 59, Ile 60, Leu 22, Phe 31 and Phe 34 and hence, to enhancing potency. The propargyl-linked antifolates are efficient ligands with a high ratio of potency to the number of non-hydrogen atoms and represent a potentially fruitful avenue for future development of antineoplastic agents.     

Linear,parameter-varying control of a supercavitating vehicle

A systematic approach to parameter-dependent control synthesis of a high-speed supercavitation vehicle (HSSV) is presented. The aim of the control design is to provide robust reference tracking across a large flight envelope, while directly accounting for the interaction of liquid and gas phases with the vehicle. A nonlinear dynamic HSSV model is presented and discussed relative to the actual vehicle. A linear, parameter-varying (LPV) controller is synthesized for angle rate tracking in the presence of model uncertainty. The control design takes advantage of coupling in the governing equations to achieve improved performance. Multiple LPV controllers synthesized for smaller overlapping regions of the parameter space are blended together, providing a single controller for the full flight envelope. Time-domain simulations implemented on high-fidelity simulations, provide insight into the performance and robustness of the proposed scheme.