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11.
S Becker C Rinne U Hofs?ss HD Klenk E Mühlberger 《Canadian Metallurgical Quarterly》1998,249(2):406-417
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The ST-16 antigenic specificity of the HLA-B locus is defined as a B39 variant of Mexican-Americans. Nucleotide sequencing of cDNA shows the ST-16 allele (B*3905) differs from B*39011 by a single substitution that substitutes tyrosine for aspartic acid at position 74 of the mature class I heavy chain. The complete coding region sequence for the common caucasoid allele encoding the B38 antigen has been determined. This B*3801 allele differs from B*3802 at two nucleotide substitutions within the Bw4 sequence motif. B*3801 and B*3802 may have been derived independently from B*39011 by conversion events with B alleles donating distinctive Bw4 motifs. A novel allele B*39022 derived from a Colombian Indian differs from the B*39021 allele of Japanese origin at two widely separated silent substitutions. Comparison of sequences for the known B16 alleles suggest that B*39021 and B*39022 were independently derived by recombination from B*39013 and B*39011 respectively. 相似文献
13.
M Adachi CJ Dickens J Hetherington HD Hoskins AG Iwach PC Wong N Nguyen AS Ma 《Canadian Metallurgical Quarterly》1997,104(12):2121-2125
OBJECTIVE: The purpose of this study is to determine the efficacy of initial trabeculotomy in the patient with aniridic glaucoma. DESIGN: Clinical charts were reviewed. PARTICIPANTS: Twenty-nine eyes of 16 patients with aniridia were studied. INTERVENTION: Glaucoma surgery was performed. As an initial procedure, trabeculotomy was performed in 12 eyes, other surgery was performed in 17 eyes (trabeculectomy, 5; goniotomy, 5; other, 7). MAIN OUTCOME MEASURES: Success was defined as an intraocular pressure (IOP) of 21 mmHg or lower, and no further surgery was performed. RESULTS: Ten (83%) of 12 eyes obtained IOP control after first (6 eyes) or second (4 eyes) trabeculotomy with a mean follow-up period of 9.5 years. Five eyes maintained visual acuity of 20/40 to 20/200. No serious complications were found after trabeculotomy. Three (18%) of 17 eyes were controlled with the first glaucoma surgery other than trabeculotomy (goniotomy, trabeculectomy, trabeculectomy combined with trabeculotomy, and Molteno implant). Good IOP control was obtained in 8 (47%) of 17 eyes after several surgeries with a mean follow-up period of 10.4 years. Four of 17 eyes became phthisical. CONCLUSION: This study suggests that trabeculotomy is the preferred initial operation for uncontrolled glaucoma with aniridia. 相似文献
14.
The application of gene therapy techniques to the clinical problem of coronary restenosis has generated tremendous attention and enthusiasm. Use of gene transfer technology to prevent a common intractable illness would represent a watershed event for human gene therapy. However, the time is not yet right to initiate gene therapy trials for restenosis. The biology of restenosis is incompletely understood, catheter-based gene delivery is poorly adapted to the coronary circulation, and current gene transfer vectors are ill-suited for safe and effective gene delivery to the coronary artery wall. Basic research designed to overcome these obstacles is currently more appropriate than the initiation of clinical trials. 相似文献
15.
喜欢欣赏3D大片的你,有否觉得沉重的3D眼镜让你鼻梁倍感压力？有否觉得3D眼镜束缚了你的视野？连2012广州海心沙跨年盛典都采用裸眼3D舞台了,你还固执地坚持一定要带上眼镜看3D吗？扔掉眼镜,一同感受裸眼3D的魅力吧! 相似文献
16.
当前主流安卓平板电脑存储容量依旧以8GB为主,除掉系统和必要软件占用空间后,消费者实际能使用的存储空间在5GB左右,用于安装软件足矣,不过对于电影、电视剧迷来说,5GB空间远远不够。于是, 相似文献
17.
“用音乐唤醒你的耳朵!”主打多媒体影音应用的华硕N系列笔记本以出色的音效受到了市场众多消费者青睐,除了配备高品质扬声器、拥有Sonicmaster“美声大师”音效系统外, 相似文献
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正体验过SSD固态硬盘的速度绝对不会想再忍受HDD机械硬盘的"龟速",面对大容量SSD固态硬盘不断刷新的最低价,有多少人能不动心?从台式机到笔记本,全方位的SSD升级势在必行。相对于看主控选SSD固态硬盘而言,如何分辨SSD固态硬盘的接口对于普通消费者而言恐怕更加实用。让我们从接口入手,一步一步了解SSD固态硬盘的奥秘吧! 相似文献
20.
正英特尔南下攻略的成功,也推动了低价Widnows 8平板的崛起,习惯了安卓平板电脑的亲们,在使用Windows 8平板时总容易遇到这样那样的问题,尤其是联网激活的异常,让不少购买预置正版Windows 8平板的用户大感郁闷,笔者在此特以昂达Windows 8平板为例,对Windows 8平板使用过程中遇到的系统和软件激活问题进行讲解。 相似文献