Influence of craniofacial surgery on the social attitudes toward the malformed and their handling in different cultures and at different times: a contribution to social world history

A historic overview including the European, American, Asian, and African continents is given on attitudes toward and the handling of humans with congenital malformations in ancient cultures and on pertinent customs in some prehistoric peoples. Figures of early works of art showing malformed individuals are presented testifying to this worldwide and timeless problem of humankind. In parallel, analogous patient photographs from our hospital before and after reconstructive surgery are shown. Philosophies of ancient Greece, rome, and China on the subject of malformed infants essentially did not differ from the known attitudes of the less developed tribes in Europe and pre-Columbian America, although the means of elimination of unwanted offspring were rather passive (exposure) than active (manual killing). A radical change in attitudes and practices occurred with the spread of the Christian religion and its political installment in Europe. The care for the underprivileged including the malformed ones was considered a Christian duty to be performed with compassion and love. In our century, the clocks have been and apparently are turned back again. Atheistic and Darwinian influences, political atheism, and the belief in "higher ethics" issued by "superman" have led to a relapse into barbarism, also within the medical system. We, as craniofacial surgeons, are privileged to have the means to turn the clocks forward again by rehabilitating the physically most underprivileged: those with conspicuous craniofacial malformations. The necessary techniques exist and are applied, as the figures of patients from our hospital demonstrate, but the will and the emotional strength for their consequent application require more than our hands.     

Effects of differences in office chair controls, seat and backrest angle design in relation to tasks

In this study the influence of chair characteristics on comfort, discomfort, adjustment time and seat interface pressure is investigated during VDU and non-VDU tasks: The two investigated office chairs, both designed according to European and Dutch standards are different regarding: 1) seat cushioning and shape, 2) backrest angle and 3) controls. Thirty subjects in total, both male and female, participated in two experiments: twenty in the first and ten in the second.Significant differences are found for ease of adjustment and adjustment time of controls, independent of the tasks. Related to tasks, a significant difference was found for the backrest range of motion. For non-VDU tasks a larger range of backrest motion was preferred by 70% of the subjects. The chair design differences were most clear for comfort and adjustment time of controls, followed by comfort of backrest angle. No differences are found between seat pan comfort and discomfort, first impressions and peak interface pressure.     

Contrast-optimal k out of n secret sharing schemes in visual cryptography

Visual cryptography and (k,n)-visual secret sharing schemes were introduced by Naor and Shamir (Advances in Cryptology — Eurocrypt 94, Springer, Berlin, 1995, pp. 1–12). A sender wishing to transmit a secret message distributes n transparencies amongst n recipients, where the transparencies contain seemingly random pictures. A (k,n)-scheme achieves the following situation: If any k recipients stack their transparencies together, then a secret message is revealed visually. On the other hand, if only k−1 recipients stack their transparencies, or analyze them by any other means, they are not able to obtain any information about the secret message. The important parameters of a scheme are its contrast, i.e., the clarity with which the message becomes visible, and the number of subpixels needed to encode one pixel of the original picture. Naor and Shamir constructed (k,k)-schemes with contrast 2^−(k−1). By an intricate result from Linial (Combinatorica 10 (1990) 349–365), they were also able to prove the optimality of these schemes. They also proved that for all fixed kn, there are (k,n)-schemes with contrast . For k=2,3,4 the contrast is approximately and . In this paper, we show that by solving a simple linear program, one is able to compute exactly the best contrast achievable in any (k,n)-scheme. The solution of the linear program also provides a representation of a corresponding scheme. For small k as well as for k=n, we are able to analytically solve the linear program. For k=2,3,4, we obtain that the optimal contrast is at least and . For k=n, we obtain a very simple proof of the optimality of Naor's and Shamir's (k,k)-schemes. In the case k=2, we are able to use a different approach via coding theory which allows us to prove an optimal tradeoff between the contrast and the number of subpixels.     

Problems with India ink skin markings

India ink skin markings allow consistently reproducible radiation field setups. The authors report a case in which a facial tattoo was applied with an injection, resulting in permanent "black eyes." The vaccination technique has not been associated with this complication.     

Value of bone marrow biopsy in the diagnosis of amyloidosis

Amyloid involvement of the bone marrow is not commonly diagnosed before necropsy. Paraffin sections of the trephine bone biopsy specimen are superior to marrow aspiration cell smears for the antemortem diagnosis. Thirteen cases of amyloidosis were diagnosed from the bone biopsy specimen during a ten-year period. Amyloid was detected in only two of the corresponding aspirates. Three morphologic patterns of marrow involvement were found: vascular, focal extravascular/perivascular, and diffuse. Five (38%) of the cases were associated with multiple myeloma. An abnormal immunoglobulin was detected in the serum or urine or both in ten of 11 cases when determined. Although the bone marrow may not be the best site for the diagnosis of amyloidosis, it should not be neglected and marrow biopsies taken for other diagnostic reasons may "incidentally" reveal amyloid. Amyloidosis should be included in the list of non-primary hematologic conditions of the bone marrow in which the trephine biopsy may prove useful for diagnosis.     

Comparison of autochthonous and allogeneic breast-tumour cells in tests for lymphocyte immunity to human tumours

Lymphocytes from 10 patients with breast carcinoma were seeded in autologous serum, on autochthonous tumour cells and allogeneic tissue-cultured breast tumour cell lines. In 4 patients, the anti-tumour cell cytotoxicity against at least one of 3 breast tumour cell lines differed significantly from that against autochthonous tumour cells. Further study of these 4 individuals (using their previously frozen lymphoid cells and sera) showed that these differences occurred because serum which decreased ("blocked") lymphocyte anti-tumour cytotoxicity when applied to one tumour cell line, could either have no effect or potentiate it when applied to another, without any consistent pattern vis-à-vis target-cell susceptibility to these different humoral effects.     

Office task effects on comfort and body dynamics in five dynamic office chairs

In the present study, we investigated the effect of office tasks on posture and movements in field settings, and the comfort rating for chair characteristics and correlation with type of task. The tasks studied were: computer work, telephoning, desk work and conversation. Postures, movements, chair part inclinations and comfort rating data were collected from 12 subjects. Computer work showed the lowest physical activity, together with upright trunk and head position and low backrest inclination. Conversation shows the highest activity of head legs and low back together with the highest cervical spine extension. In contrast, desk work provoked the most cervical spine flexion and showed the second lowest activity. The telephoning tasks showed medium activity and the highest kyphosis. Conversation showed the highest backrest inclination. Positive comfort relations were found for computer work and a "swing system" chair, for telephoning and an active longitudinal seat rotation, and for desk work and a chair with a three-dimensionally moveable seat.     

On‐line Quality Control of Coated Glass. On‐line Qualitätskontrolle von beschichtetem Glas

Properties of optical coatings (e.g. low‐e or solar control) can be described and controlled using transmittance, reflectance and sheet resistance measurements. Multiple in situ transmittance measurement points allow a quick response to adjust different coating processes (layer thickness and homogeneity). For the final characterization of the coated substrate ex situ transmittance, reflectance and sheet resistance measurements are used. Accurate and reproducible measurements in a combination with Reverse Engineering methods admit monitoring all layers and in this way detecting slight drifts.