米糠油的营养与应用综述（网络首发、推荐阅读）

米糠油或稻米油从很多方面来看都是一种健康植物油。与其他植物油相比,米糠油具有均衡的脂肪酸,拥有较高含量且独特的微量成分、微量营养素或不皂化物。目前研究表明,米糠油中的谷维素含量超过1.5%,提供了营养和药物功能。更多的研究在开展中来证明米糠油多方面的广泛功能。米糠油富含植物甾醇,有许多研究关注其营养应用价值。此外,米糠油含有生育酚和生育三烯酚,尤其后者具有许多特殊功能,如预防乳腺癌等。越来越多地营养学或生物学研究证明,当米糠油适当加工后在食品中使用时,具有特殊功能。因此,在学术研究和产业实践中,都在探索米糠油在食品和制药领域的应用。对米糠油的营养应用进展做简要综述。     

改性纳米二氧化钛光催化降解聚乙烯薄膜的研究

以硬脂酸钠改性的纳米TiO2为光催化剂,与LDPE树脂制备了nano-TiO2/PE复合薄膜.研究了该薄膜在紫外光照射条件下的降解性能,并进行了SEM、FI-IR、VHX-100数码显微镜等分析,测试了薄膜经辐照前后的力学性能、质量变化和分子量变化.研究结果表明,该薄膜在紫外光照射下降解性能明显提高,薄膜在40W、254nm的紫外光照射120h后,粘均分子量(Mη)降低27.1%,拉伸强度降低49.1%,断裂伸长率降低91.3%;照射144h后质量损失达16%(质量分数);辐照后薄膜的羰基含量升高.     

Quantitation of vancomycin and its crystalline degradation product (CDP-1) in human serum by high performance liquid chromatography

Mantle cell lymphoma (MCL) patients represent a difficult problem, sometimes to establish the diagnosis but mostly because of their refractoriness to standard lymphoma treatments. Which treatments to apply and to whom is not yet defined. In this study, we attempted to analyze the clinical features, to identify the major prognostic factors, and to evaluate the outcome of 121 MCL patients treated in our institution between 1979 and 1997. Clinical data, treatment modalities, and International Prognostic Index (IPI) score were evaluated. Median age was 63 years. Patients usually presented with advanced stage disease (87%), disseminated lymph nodes (57%), bone marrow involvement (79%), but with a good performance status (PS) (81%). Lymphocytosis >4000/microl and/or peripheral blood involvement was present in 36% of cases, and gastrointestinal disease in 18%. The t(11;14)(q13;q32) and/or bcl-1 rearrangement was detected in 47/57 studied cases. Median overall survival (OS) was 3.12 years and a longer survival was significantly associated with younger age (<70 years), good PS (<2), localized disease (stage I-II), fewer than two extra-nodal sites, absence of spleen or peripheral blood involvement, normal serum LDH and beta2-microglobulin levels, and hemoglobin level greater than 12 g/dl. However, the IPI failed to identify patients with longer OS and in a multiparametric analysis, only older age, hemoglobin less than 12 g/dl, poor PS, and blood involvement were associated with a poorer outcome. Treatment modalities had no impact on survival with 75% of patients relapsing or progressing. Our data showed that the poor outcome of MCL patients is mainly related to adverse patient characteristics, a highly disseminated tumor, and some unknown parameters associated with the refractoriness to standard therapy.     

柳树叶中原花青素的提取与含量测定

以乙醇提取柳树叶的原花青素,考察了乙醇浓度、料液比、提取时间和提取温度等对提取率的影响。结果表明,乙醇浓度70%,料液比1∶20,提取温度70℃,提取时间120 min为最佳提取条件。运用香草醛-盐酸显色法,对最佳提取条件下提取的柳树叶中原花青素含量进行测定,测得绥化地产柳树叶中原花青素含量为10.77 mg/g。     

Determinant spreading associated with demyelination in a nonhuman primate model of multiple sclerosis

Definition of the immune process that causes demyelination in multiple sclerosis is essential to determine the feasibility of Ag-directed immunotherapy. Using the nonhuman primate, Callithrix jacchus jacchus (common marmoset), we show that immunization with myelin basic protein and proteolipid protein determinants results in clinical disease with significant demyelination. Demyelination was associated with spreading to myelin oligodendrocyte glycoprotein (MOG) determinants that generated anti-MOG serum Abs and Ig deposition in central nervous system white matter lesions. These data associate intermolecular "determinant spreading" with clinical autoimmune disease in primates and raise important issues for the pathogenesis and treatment of multiple sclerosis.     

Radiographic evaluation of complications after jejunoileal bypass surgery

A retrospective analysis of 89 patients who underwent jejunoileal bypass surgery for morbid obesity disclosed 33 complications that were detected radiographically. Intestinal obstruction (10.1% of patients), cholecystitis (5.6%), renal stones (4.5%), peptic ulcer (3.4%), megacolon (6.7%), and elongation of the small intestine with hypertrophy of the mucosal folds of the jejunum (6.7%) were diagnosed solely by radiographic means.