Optimisation of rancidity stability in long‐chain PUFA concentrates obtained from a rainbow trout (Oncorhynchus mykiss) by‐product

This research was focused on the production of polyunsaturated fatty acid concentrates from a farmed rainbow trout (Oncorhynchus mykiss) by‐product (i.e. belly muscle). The effect of different process variables (urea/fatty acids (FA) contents ratio, crystallisation time and temperature and stirring speed of the urea/FA mixture) on the lipid oxidation development during the urea complexation process was investigated. For this purpose, an experimental design (26 runs) following the response‐surface methodology was developed. As a result, peroxide value and TOTOX index showed to be dependent on the crystallisation time and temperature and the urea/FA ratio, while no influence of the crystallisation stirring speed was detected on both indices; additionally, polyene index was affected by the urea/FA ratio and its interaction with the crystallisation time. An optimised desirability score near 1.0 was attained provided values of 2.8 °C, 3.05 h and 3.57 were applied for crystallisation temperature, crystallisation time and urea/FA ratio, respectively.     

Bacterial Killing by Light‐Triggered Release of Silver from Biomimetic Metal Nanorods

Illumination of noble metal nanoparticles at the plasmon resonance causes substantial heat generation, and the transient and highly localized temperature increases that result from this energy conversion can be exploited for photothermal therapy by plasmonically heating gold nanorods (NRs) bound to cell surfaces. Here, plasmonic heating is used for the first time to locally release silver from gold core/silver shell (Au@Ag) NRs targeted to bacterial cell walls. A novel biomimetic method of preparing Au@Ag core–shell NRs is employed, involving deposition of a thin organic polydopamine (PD) primer onto Au NR surfaces, followed by spontaneous electroless silver metallization, and conjugation of antibacterial antibodies and passivating polymers for targeting to gram‐negative and gram‐positive bacteria. Dramatic cytotoxicity of S. epidermidis and E. coli cells targeted with Au@Ag NRs is observed upon exposure to light as a result of the combined antibacterial effects of plasmonic heating and silver release. The antibacterial effect is much greater than with either plasmonic heating or silver alone, implying a strong therapeutic synergy between cell‐targeted plasmonic heating and the associated silver release upon irradiation. The findings suggest a potential antibacterial use of Au@Ag NRs when coupled with light irradiation, which has not been previously described.     

InGaAs PIN光电探测器的暗电流特性研究

从理论上分析了In0.53Ga0.47As PIN光电探测器在不同掺杂浓度及反向偏压下的暗电流特性,并与研制的器件的实测结果进行了比较和讨论.模拟结果表明:在低偏压下,器件中的产生复合电流起主要作用,偏压增大时,隧道电流起主要作用,且In0.53Ga0.47As光吸收层的载流子浓度对器件的暗电流有很大的影响,实测器件特性与模拟结果完全符合.文中还对器件结面积和电极尺寸等对暗电流的影响进行了比较和分析.     

Comparison of the SimPlate yeast and mould color indicator to the BAM method for quantification of fungi in naturally-contaminated foods

A total of 260 samples from six food groups (grains and grain products, tree nuts, dried fruits, fresh produce, fruit juice, and dairy products) were tested for levels of fungal contamination using the SimPlate Yeast and Mould Color Indicator (YM-CI) and the FDA official (BAM) method. Results showed that the SimPlate, in most cases, gave higher yeast and mould (YM) counts than the FDA (reference) method. Statistical analysis of the data (paired t-test) revealed that there were significant differences (α = 0.05) between the two methods for several foods tested. The SimPlate was easy to use, saved time during sample preparation and inoculation and gave results faster than the reference method. Some difficulties were encountered when spreading moulds were present.     

CO2RBFN: an evolutionary cooperative–competitive RBFN design algorithm for classification problems

This paper presents a new evolutionary cooperative–competitive algorithm for the design of Radial Basis Function Networks (RBFNs) for classification problems. The algorithm, CO²RBFN, promotes a cooperative–competitive environment where each individual represents a radial basis function (RBF) and the entire population is responsible for the final solution. The proposal considers, in order to measure the credit assignment of an individual, three factors: contribution to the output of the complete RBFN, local error and overlapping. In addition, to decide the operators’ application probability over an RBF, the algorithm uses a Fuzzy Rule Based System. It must be highlighted that the evolutionary algorithm considers a distance measure which deals, without loss of information, with differences between nominal features which are very usual in classification problems. The precision and complexity of the network obtained by the algorithm are compared with those obtained by different soft computing methods through statistical tests. This study shows that CO²RBFN obtains RBFNs with an appropriate balance between accuracy and simplicity, outperforming the other methods considered.     

Quadratic cost functional for wave-front reconstruction

A quadratic cost functional for reconstruction of a high-resolution wave front from a coarse wave front is presented. The functional uses as data the position and the direction of the coarse wave front that had previously been computed with a ray-tracing method. This functional uses an optical relationship between the ray information and the wave front's shape to reconstruct a high-density wave front. The performance of the proposed functional is illustrated by reconstruction of complicated wave fronts for which this functional has an accuracy that is superior to that of conventional interpolation methods.     

Preparation and thermoluminescence properties of aluminium oxide doped with europium

There is little information concerning the use of rare earths as dopants of Al2O3. This paper presents the preparation method and the results of studying the thermoluminescence characteristics of Al2O3:Eu exposed to ultraviolet light. Phosphor powder was obtained by the evaporation method. Optimum dopant concentration was 10% at an evaporation temperature of 700 degrees C. The powder obtained was submitted to thermal treatments at high temperatures in order to stabilise the traps. Diffraction patterns showed amorphous powder up to 500 degrees C; as the temperature was raised crystalline phases of Al2O3 appeared. The photoluminescence spectrum induced by 250 nm UV light exhibited four well defined peaks characteristic of the Eu3+ ion. The glow curve exhibited two peaks at 180 and 350 degrees C. The sensitivity of Al2O3:Eu was 10 times lower than Al2O3:C. The thermoluminescence response was linear from 2.4 to 3000 microJ.cm(-2) of spectral irradiance, and the fading 2% in a month. From these results it can be concluded that Al2O3:Eu has potential as an UV dosemeter.     

Regularization methods for processing fringe-pattern images

A powerful technique for processing fringe-pattern images is based on Bayesian estimation theory with prior Markov random-field models. In this approach the solution of a processing problem is characterized as the minimizer of a cost function with terms that specify that the solution should be compatible with the available observations and terms that impose certain (prior) constraints on the solution. We show that, by the appropriate choice of these terms, one can use this approach in almost every processing step for accurate and robust interferogram demodulation and phase unwrapping.     

Short-term hemodynamic effects of mibefradil in dogs with chronic heart failure: comparison with diltiazem

Despite the marked vasodilator and antiischemic actions of existing calcium channel blockers, their use in the treatment of patients with chronic heart failure (HF) remains highly controversial. We compared the short-term hemodynamic effects of i.v. mibefradil, a predominant T-type calcium channel blocker with only partial L-type calcium channel antagonism, and diltiazem, a selective L-type calcium channel antagonist in dogs with chronic HF. Each of three drugs namely, mibefradil, diltiazem and normal saline (as placebo control), were studied in random order (6 days between each drug intervention), in each of 8 dogs with chronic HF produced by multiple intracoronary microembolizations. Intravenous mibefradil and diltiazem were administered as a 100 micrograms/kg bolus followed by a continuous infusion of 6 and 4 micrograms/kg/min, respectively, for 15 min. Equal volumes of normal saline were administered in an identical fashion. In all instances, hemodynamics were obtained at base line and at 5, 10, 15, 30 and 60 min after bolus drug administration. Left ventriculograms were obtained at baseline, and at 15 and 60 min after bolus drug administration. Saline infusion had no effects on hemodynamic or angiographic indexes of left ventricular (LV) function. At 15 min, mibefradil caused significant increases of LV stroke volume and LV ejection fraction compared to baseline (40 +/- 5 vs. 31 +/- 3 ml, P < .05 and 41 +/- 1 vs. 28 +/- 1%, P < .05, respectively). In contrast, at 15 min, diltiazem produced no significant changes of LV stroke volume or ejection fraction compared to baseline despite reducing mean aortic pressure to the same extent as mibefradil. Short-term i.v. mibefradil improves LV function in dogs with chronic HF. The beneficial effects of mibefradil compared to diltiazem may be a consequence of T-type calcium channel selectivity resulting in a vasodilatory response that is free of negative inotropy.