Grain coarsening tests were carried out on Al-4.5 pct Cu and Al-4.5 pct Si alloys. The effects of three variables, melt composition, pour temperature, and mold temperature, were determined. It was found that the macrostructure generally coarsened with increased pour and mold temperatures. Coarsening was extreme in the unrefined alloys but was retarded by the active grain refiners like titanium and columbium. The effect of boron was spectacular in suppressing coarsening tendencies. The results of the investigation support the carbide theory of nucleation as opposed to the peritectic theory. 相似文献
Quality criteria used in the computer-aided design and analysis of casting processes typically relate geometric, thermal, or solidification parameters to structural features such as centerline shrinkage and microporosity. Quality criteria for the prediction of porosity in castings have been used successfully in steel, but the application of criteria functions to nonferrous alloys has been less successful. Recent work suggests that the dominating mechanism that determines the amount and distribution of porosity in castings is strongly dependent on the solidification mode of the alloy and the solidification conditions. Accordingly, casting processes and alloy types are divided into four groups, and a different set of criteria functions are obtained for each group. 相似文献
We have developed an IT governance disclosure framework to examine how firms communicate their IT governance activities. Using this framework for a sample of 200 commercial banking firms, our empirical assessment indicates that differences in the level of disclosure are systematically related to differences in institutional settings. We also find that firms with relatively good corporate governance practices consider IT performance measurement matters to be highly important when informing and communicating with shareholders. 相似文献
Wireless sensor networks (WSN) is considered as one of the exploring technology for its deployment of the massive number of dedicated sensor nodes which sense the environment and collect the data. The collected data are sent to the sink node through the intermediate nodes. Since the sensors node data are exposed to the internet, there is a possibility of vulnerability in the WSN. The common attack that affects most of the sensor nodes is the Distributed Denial of Services (DDoS) attack. This paper aims to identify the DDoS (Flooding) attack quickly and to recover the data of sensor nodes using the fuzzy logic mechanism. Fuzzy based DDoS attack Detection and Recovery mechanism (FBDR) uses type 1 fuzzy logic to detect the occurrence of DDoS attack in a node. Similarly fuzzy- type 2 is used for the recovery of data from the DDoS attack. Both the type 1 fuzzy-based rule and type 2 fuzzy-based rule perform well in terms of identifying the DDoS attack and recover the data under attack. It also helps to reduce the energy consumption of each node and improves the lifetime of the network. The proposed FBDR scheme is also compared with other related existing schemes. The proposed method saves energy usage by up to 20% compared with the related schemes. The experimental results represent that the FBDR method works better than other similar schemes.
OBJECTIVE: Decreased cerebral blood flow (CBF) and cerebral ischemia occurring immediately after subarachnoid hemorrhage (SAH) may be caused by acute microvascular constriction. However, CBF can also be influenced by changes in intracranial pressure (ICP) and cerebral perfusion pressure (CPP). The goal of these experiments was to assess the significance of acute vasoconstriction after SAH and its relationship to changes in CBF, ICP, CPP, and extracellular glutamate concentrations. METHODS: Three experiments were performed using the endovascular filament technique to produce SAH. In the first experiment, CBF, ICP, and CPP were measured for 60 minutes after SAH (n = 21) and were correlated with the 24-hour mortality rate. In the second experiment, rats undergoing SAH (n = 23) or a sham procedure (n = 7) were perfused 60 minutes after SAH for measurement of the circumference and wall thickness of the internal carotid and anterior cerebral arteries and correlation with CBF, ICP, and CPP. In the third experiment (n = 11), extracellular glutamate concentrations determined by hippocampal and cortical microdialysis and high performance liquid chromatography were correlated with physiological changes. RESULTS: CBF reductions to less than 40% of baseline for 60 minutes after SAH predicted 24-hour mortality with 100% accuracy and were used to define "lethal" SAH. In contrast, ICP and CPP 60 minutes after SAH were not correlated with the mortality rate. The vascular circumference was significantly smaller in lethal than in sublethal SAH or sham-operated rats (P < 0.001). Vessel measurements were correlated with both CBF and hemorrhage size (P < 0.01). Extracellular glutamate concentration increased to 600% of baseline after lethal SAH in both hippocampus and cortex and was inversely correlated with CBF (r = 0.9, P < 0.001) but did not increase after sublethal SAH. CONCLUSION: Acute vasoconstriction after SAH occurs independently of changes in ICP and CPP and is associated with decreased CBF, larger hemorrhage size, persistent elevations of extracellular glutamate, and poor outcome. Acute vasoconstriction seems to contribute directly to ischemic brain injury after SAH. Further evaluations of pharmacological agents with the potential to reverse acute vasoconstriction may increase CBF and improve outcome. 相似文献
The serum of some patients with insulin-resistant "diabetes" contains antibodies that bind to and block the cell membrane receptors for insulin. In this report, we have characterized the effects of the antireceptor antibodies on the interaction of (125)I-insulin with its receptor on the human lymphoblastoid cell line IM-9. Up to 95% of specific insulin binding can be inhibited by pretreatment of the cells with these immunoglobulins. The onset of the inhibitory effect is time- and temperature-dependent, and the effect is reversed extremely slowly if the cells are suspended in a large excess of antibody-free buffer. These features of antibody binding can be easily distinguished from those for insulin binding to its receptor. The inhibitory effect of the antibodies can be reversed by exposure of the cells to conditions known to elute surface immunoglobulins. The three antireceptor sera studied appear to alter the insulin-receptor interaction in different ways. Two antisera markedly reduce receptor affinity through combined effects on the insulin association and dissociation rates, and, additionally, have smaller effects on available receptor number. A third antiserum primarily affects available receptor number and has little effect on receptor affinity. All three antisera inhibit the capacity of insulin to promote negatively cooperative site-site interactions among insulin receptors. The data suggest that these autoantibodies to the insulin receptor bind to different determinants on the receptor and may therefore be useful as unique probes of insulin receptor structure and function. 相似文献
Beta brass single crystal, bicrystal and tricrystal stress strain behavior were determined for a series of isoaxial specimens
in which the bicrystals and tricrystals were incompatible in shear along the grain boundary. Volume fractions of grain boundary
deformation were also determined to ascertain the effect of increased constraint on grain boundary strengthening. It was found
that bicrystal flow stress was considerably higher than single crystal flow stress and that tricrystal strain hardening was
only slightly larger than that of the bicrystal. For the tricrystals the grain boundary deformation zone is larger than that
of corresponding bicrystals because of both configurational and constraint effects. This larger zone indicates that secondary
stresses extend further from the boundary in tricrystals than in bicrystals. It was concluded that despite increased constraint,
, the average grain boundary stress for the tricrystals, is smaller than that for corresponding bicrystals and that because
of the increased extent of the secondary stress,σbi, the stress in the center component away from the grain boundary, is higher than that of the single crystal at corresponding
strains. The relationship of these observations to corresponding stresses in polycrystalline material is examined.
where Taek Dong Lee was formerly a Graduate Student.
This paper is based on a thesis to be submitted by Taek Dong Lee in partial fulfillment of the requirements for the degree
of Doctor of Philosophy at Polytechnic Institute of New York. 相似文献
In this paper we discuss a real-life case study to optimize the logistics network for the collection of containers from end-of-life
vehicle dismantlers in the Netherlands. Advanced planning concepts, such as dynamic assignment of dismantlers to logistic
service providers, are analyzed using a simulation model. Based on this model, we periodically solve a vehicle routing problem
to gain insight into the long-term performance of the system. The vehicle routing problem considered is a multi-depot pickup
and delivery problem with alternative delivery locations. A special characteristic of the problem is the limited vehicle capacity
of two containers. We solve this problem with a heuristic based on route generation and set partitioning. 相似文献
The authors explored the prognostic value of 3 different types of catastrophic cognitions in the treatment of panic disorder with and without mild-to-moderate agoraphobia using a sample of 143 participants who received either cognitive-behavioral therapy (CBT) or imipramine in a randomized controlled trial. Stronger fears of social catastrophes both prior to and following treatment with CBT or imipramine were associated with a poorer outcome. In contrast, cognitions involving physical or mental catastrophes were unrelated to outcome, regardless of whether these thoughts were measured prior to or following treatment. These findings are consistent with the notion that although the intensity of physical catastrophe cognitions may best discriminate between panic disorder and other anxiety disorders, it is the intensity of social catastrophe cognitions that is most closely tied to success in treating this disorder. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献