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21.
Reproductive loss: barriers to psychoanalytic treatment 总被引:1,自引:0,他引:1
IG Leon 《Canadian Metallurgical Quarterly》1996,24(2):341-352
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IG Gazaryan IV Ouporov TA Chubar VA Fechina EA Mareeva LM Lagrimini 《Canadian Metallurgical Quarterly》1998,63(5):600-606
The dendritic localization of mRNAs has been proposed to underlie the structural and functional polarity of neurons, as well as certain aspects of synaptic plasticity. Even though there is no conclusive evidence that such a localization is a physiological requirement, studies of mRNA localization in relation to function in other cell types and recent experiments on synaptic plasticity suggest that this proposal may be correct. 相似文献
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Diets, energy expenditures, physical and mental performance, anthropometric indices, ascorbic acid excretion, and morbidity rates were studied in 7-9-year-old schoolchildren of Monchegorsk, Murmansk Region. The alimentary features found served as the basis for developing sanitary recommendations to optimize diets and to promote children's health. 相似文献
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A model of postsynaptic processes leading to a prolonged posttetanic modification (potentiation and depression) in the efficacy of the excitatory and inhibitory inputs to the neuron CA3 of the hippocampus was developed. The model enables one to estimate changes in postsynaptic potentials depending on the extent of receptor phosphorylation, which is determined by Ca(2+)-dependent changes in secondary messengers. 相似文献
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OBJECTIVE AND DESIGN: The limitation of activity and its modification by therapy in an experimental arthritis was studied. SUBJECTS: Female hamsters in groups of six per treatment were used. TREATMENT: An acute arthritis was induced by intraarticular injection of 0.1 microgram lipopolysaccharide (LPS) in hamsters with free access to running wheels. Tenidap at 100 mg%, and piroxicam and indomethacin at 30 mg% were administered in the hamster's normal diet. METHODS: Activity was monitored and analysed by computer. Plasma blood levels of drugs were determined by high pressure liquid chromatographic (HPLC) analysis. RESULTS: Hamsters normally run 10-15 km/day. That distance was reduced to less than 2 km/day after arthritis induction. Speed of movement, essentially the equivalent of walking time, was reduced 40% by the arthritis. However, the time spent in movement (activity time) was more severely affected by arthritic disease. Therapy gave a modest 1.3-fold increase in speed of movement, but a highly significant 2-fold increase in activity time. CONCLUSIONS: The effects of arthritis on activity in this animal model suggest that time spent in movement (activity time) should be considered as an outcome measure in clinical studies. These observations may also help explain why the modest disease improvements obtained with cyclooxygenase inhibition are valued. From a patient perspective, a doubling of activity time is a highly significant improvement in quality-of-life. 相似文献