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61.
This research investigates the development of electronic commerce in Malaysia. It reviews the nation's e-commerce readiness and surveys local firms, a majority of them small- and medium-sized enterprises (SMEs), on their Web presence and e-commerce initiatives, management, capabilities and performance. Overall, while e-commerce in Malaysia is in its formative phases, a majority of firms in the survey sample have progressed beyond brochureware into the interactions phase; few have reached the e-commerce phase but many are planning to. They are driven primarily by marketing considerations and have seen the greatest impact of e-commerce on their marketing and overall business operations. Taking the lead are SMEs in IT/Internet services and solutions that see great opportunities in the nation's need to build the foundation layers for its emerging Internet economy. Most reluctant and least satisfied to date are SMEs in manufacturing that find the business-to-business sector largely undeveloped. The government can take some credits for its leadership in addressing the barriers to e-commerce development but the most significant barriers falls squarely within the private sector's domain. They will have to be overcome by entrepreneurial talents and management foresight.  相似文献   
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TEM images of thin foils with quasi-globular particles are examined by means of two methods of spatial statistics. The spatial arrangement of particle reference points is described by means of quadrat count statistics and by polygonal method (the analysis of the Voronoi mosaic generated by patterns of particle reference points). A good agreement between the both approaches is found, the polygonal method is more sensitive and its results are more conclusive.  相似文献   
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MEAN STRESS EFFECTS ON LOW CYCLE FATIGUE FOR A HIGH STRENGTH STEEL   总被引:6,自引:0,他引:6  
Abstract— ASTM A723 Q & T steel with a yield strength and ultimate strength of 1170 and 1262 MPa respectively was evaluated for mean stress-strain effects under smooth specimen axial strain controlled low cycle fatigue conditions with strain ratios R of −2, −1, 0, 0.5 and 0.75. Cycles to failure ranged from 15 to 105. Cyclic stress-strain response based upon half-life hysteresis loop peaks were similar for all R ratios. Mean stress relaxation occurred for R ≠−1 only when plastic strain amplitudes were present and this occurred above total strain amplitudes of 0.005. Thus, mean stress relaxation was completely dependent upon cyclic plasticity. Mean strains did not affect low cycle fatigue life unless accompanied by half-life mean stress. Tensile mean stress was detrimental and compressive mean stress was beneficial and these effects only occurred at strain ampltidues below 0.005. Three different mean stress models were used to evaluate the low cycle fatigue data and the SWT log-log linear model best represented the data. These results can be used with the local notch strain fatigue life prediction methodology.  相似文献   
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BACKGROUND: The precise mechanisms involved in islet xenograft rejection remain unknown. The purpose of the present study was to determine cellular mechanisms responsible for islet xenograft rejection in the liver to facilitate finding a procedure for prevention of immune rejection. METHODS: Hepatic mononuclear cells (MNC) as well as splenocytes, peripheral blood MNC, and thymocytes from streptozotocin-induced diabetic mice (BALB/c) rejecting the intrahepatic rat (Lewis) islet xenografts were isolated and examined by two-color FACS analysis. RESULTS: The characteristic finding of the hepatic MNC from the mice rejecting islet xenografts compared with mice receiving isografts was a significant increase in the yield as well as in the percentage of the cells expressing CD3+ interleukin-2 receptor (IL-2R) alpha- beta+, CD3+ CD8alpha+ beta+, and T cell receptor (TCR) alphabeta+ lymphocyte function-associated antigen-1+. The expression of CD3 and TCR alphabeta of these T cells was found to be of intermediate intensity (TCR(int) cells). The expansion of these TCR(int) cells occurred predominantly in the liver. There was no significant difference in the cells expressing CD3+ IL-2R alpha+, CD3+ CD4+, CD3+ TCRgammadelta+, CD3- IL-2Rbeta+ (natural killer cells), and B220+ (B cells). In vivo administration of anti-IL-2Rbeta monoclonal antibody directed to the expanded cells produced a prevention of rejection. CONCLUSIONS: These findings suggest that islet xenograft rejection in the liver from rat to mouse is an event for which the TCR(int) cells are responsible.  相似文献   
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AIM: This study of trimetasidine effects on plasmic hemostasis and blood biochemistry in patients with chronic heart failure (CCF) of NYHA functional class II-III. MATERIALS AND METHODS: This study enrolled 30 patients (24 males and 6 females) aged 40-72 years with class II-III CCF, postinfarction cardiosclerosis and ejection fraction under 40%. Previously the patients received perindopril (the inhibitor of angiotensin converting enzyme) in daily dose 2-4 mg, on-demand digoxin and diuretics. Trimetasidine was given in a daily dose 60 mg for 6 months. Before and after the treatment the patients' blood was examined for: levels of factors VII and X of antithrombin III coagulation, soluble fibrinomonomeric complexes (SFMC), fibrinogen, glucose, uric acid, creatinines, total cholesterol, high density lipoprotein, triglycerides, AST, ALT, LDH, acid phosphotase, gamma-GT, sodium, potassium, activated partial thrombin time. RESULTS: Initially, the patients had a 23.9% increase in the levels of factors VII and X, a 14.3% decrease of antithrombin III, 29.8 and 227.6% rise in concentrations of fibrinogen and SFMC, respectively, compared to controls. Aftertreatment values of fibrinogen, factors VII and X, SFMC fell by 21.1, 17 and 35.5%, respectively. The thrombin time arose by 17.9% (p > 0.05). Insignificant inhibition was registered in the activity of acid phosphotase and gamma-GT. Glucose, AST, ALT, LDH levels remained unchanged. Plasma creatinine tended to lowering. Total cholesterol insignificantly increased at high levels of HDL cholesterol (p > 0.05) and reduced levels of triglycerides (p > 0.05). CONCLUSIONS: Trimetasidine therapy, given after conventional treatment with diuretics, digoxin, inhibitor of angiotensin-converting enzyme, aspirin has a beneficial effect in patients with circulatory deficiency through improving hemostatic and biochemical parameters.  相似文献   
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Thermal conductivity and electrical resistivity of porous materials, including 304L stainless steel Rigimesh, 304L stainless steel sintered spherical powders, and OFHC sintered spherical powders at different porosities and temperatures are reported and correlated. It was found that the thermal conductivity and electrical resistivity can be related to the solid material properties and the porosity of the porous matrix regardless of the matrix structure. It was also found that the modified Wiedemann-Franz-Lorenz relationship is valid for the porous materials under consideration. For high conductivity materials, the Lorenz function and the lattice component of conductivity depend on the material and are independent of the porosity. For low conductivity, the lattice component depends on the porosity as well.  相似文献   
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