Aevit and glutamic acid in the treatment of patients with bronchial asthma

To elucidate the effect of antioxidants aevit and glutaminic acid on the course of bronchial asthma (BA) and free radical processes in this disease, 54 BA patients were divided into 2 groups: glucocorticoid-untreated and glucocorticoid-treated. Each of two subgroups made of these groups either received antioxidants (AO) or not. The response was assessed by clinical BA symptoms and free radical processes reflecting production of active oxygen forms by leukocytes (PAOFL) and free radical peroxidation (FRPO). PAOFL was studied using luminol-dependent chemiluminescence (CL). CL basal and stimulated values were calculated. FRPO was measured by plasma levels of malonic dialdehyde. Aevit and glutaminic acid treated BA patients improved clinically and exhibited reduced CL of PAOFL and malonic dialdehyde in plasma compared to BA patients on conventional therapy or conventional therapy plus glucocorticoids. Aevit and glutaminic acid are recommended for BA patients.     

Kinetics of the colony-forming capacity of bone marrow cells following hydrocortisone administration to mice

A study was made of the dynamics of the colony-forming and migration capacity of the polypotent stem hemopoietic cells of the bone marrow of the F1 (CBA X C57BL) mice after the hydrocortisone administration. The relative count of the stem hemopoietic cells in the bone marrow increased on the 3rd day after the hydrocortisone administration. This elevation was maximal on the 5th day after the hydrocortisone administration. On the 8th day the stem hemopoietic cell count decreased to the normal level.     

Vitamin B12-binding substances elaborated by the mucous membrane of the stomach]

Accurate electrocardiographic diagnosis of myocardial ischemia or infarction is difficult in patients with the Wolff-Parkinson-White syndrome; however, myocardial ischemia may also have profound effects on the electrophysiologic characteristics of the bypass tract in these patients. Comparison of studies performed during and two months following an episode of significant myocardial ischemia demonstrated substantial prolongation of the refractoriness of the bypass tract during the period of ischemia. Bypass refractoriness was prolonged by 196 msec, yet atrioventricular nodal refractoriness was not significantly different from normal. These studies, therefore, suggest that, on occasion, the presence of acute myocardial ischemia may, in fact, obscure the electrocardiographic diagnosis of the Wolff-Parkinson-White syndrome.