Recent trends and open issues in reverse engineering

This paper discusses recent trends in the field of reverse engineering, particularly those highlighted at the Second Working Conference on Reverse Engineering, held in July 1995. The trends observed include increased orientation toward tasks, grounding in complex real-world applications, guidance from empirical study, analysis of non-code sources, and increased formalization. The paper also summarizes open research issues and provides pointers to future events and sources of information in this area.     

Clinical, neurophysiological and hemodynamic effects of a new nondepolarizing myorelaxant mivacurium in heart surgery patients]

Thirty patients aged 23 to 65 years with ASA class III operated on the heart under total intravenous anesthesia were examined after the Good Clinical Practice protocol. Mivacurium in bolus dose of 0.2 mg/kg was injected for intubation of the trachea; neuromuscular blocking (NMB) was maintained by a repeated injection of the drug in a dose of 0.15 mg/kg, after which it was infused at a rate of 1 to 10 micrograms/kg/min. Accelerometric control of neuromuscular conduction was carried out by the Organon (Belgium) TOF-Guard device. Central and peripheral hemodynamics was monitored. Side effects of the drug were recorded. Bolus injection of mivacurium in a dose of 0.2 mg/kg caused T1 suppression (90%) after 2.6 +/- 0.7 min. Maximal (97.7 +/- 4.5%) suppression was observed after 4.17 +/- 2.5 min. The conditions of intubation of the trachea after 3.9 +/- 1.8 min in the presence of 78 to 100% T1 suppression (97.7 +/- 4.5%) were considered excellent or good in 96.6% of cases. Clinically and neurophysiologically sufficient muscle relaxation after the first injection of the drug persisted for 27.7 +/- 7.3 min. Minimal rate of infusion for maintaining the NMB at 95 +/- 4% level of T1 suppression was 6.3 +/- 1.7 micrograms/kg/min. Bolus injection of mivacurium in a dose of 0.2 mg/kg for 60 sec involved a 1-3-min drop of the mean arterial pressure by 10.5% and a 10.3% decrease of heart rate. Repeated bolus injection of the drug in a dose of 0.15 mg/kg and its infusion did not change the peripheral and central hemodynamics. The most typical side effect of the drug in a dose of 0.2 mg/kg is short-term reversible reddening of the skin of the face and neck, observed in 20% of patients. The results permit us to consider mivacurium as an effective, safe, and controllable agent, which can be used in cardiosurgical patients.     

Iris Recognition Using Wavelet Features

The traditional iris recognition systems require equal high quality human iris images. A cheap image acquisition system has difficulty in capturing equal high quality iris images. This paper describes a new feature representation method for iris recognition robust to noises. The disc-shaped iris image is first convolved with a low pass filter along the radial direction. Then, the radially smoothed iris image is decomposed in the angular direction using a one-dimensional continuous wavelet transform. Each decomposed one-dimensional waveform is approximated by an optimal piecewise linear curve connecting a small set of node points. The set of node points is used as a feature vector. The optimal approximation procedure reduces the feature vector size while maintaining recognition accuracy. The similarity between two iris images is measured by the normalized cross-correlation coefficients between optimal curves. The similarity between two iris images is estimated using mid-frequency bands. The rotation of one-dimensional signals due to the head tilt is estimated using the lowest frequency component. Experimentally we show the proposed method produces superb performance in iris recognition.     

Nondieting versus dieting treatment for overweight binge-eating women.

This study evaluated the effectiveness of nondieting versus dieting treatments for overweight, binge-eating women. Participants (N?=?219) were randomly assigned to 1 of 3 groups: diet treatment (DT), nondiet treatment (NDT), or wait-list control (WLC). DT received a balanced-deficit diet reinforced with behavioral strategies. NDT received therapy designed to help participants break out of their dieting cycles. Treatment in both conditions was administered in weekly groups for 6 months, followed by 26 biweekly maintenance meetings, for a total of 18 months of contact. At 6 months posttreatment, DT lost 0.6 kg while NDT gained 1.3 kg. Both treatment groups reduced their Binge Eating Scale scores significantly more than WLC. At 18-month follow-up, both treatment groups experienced weight gain but maintained similar reductions in binge eating. Results indicate that neither intervention was successful in producing short- or long-term weight loss. Therapist biases, which may have affected treatment integrity, and other methodological issues are discussed in relation to the small weight losses achieved. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Vancomycin penetration into biofilm covering infected prostheses and effect on bacteria

To evaluate the adequacy of penetration of antibiotics into biofilm, a novel in vitro model for prosthesis-related infection was developed. Sterile stainless steel orthopedic nuts were incubated with slime-producing Staphylococcus epidermidis. Biofilm-covered nuts were exposed to varying concentrations of vancomycin; then biofilms were harvested. Vancomycin levels in biofilm, as measured by fluorescent polarization immunoassay, far exceeded the MIC and MBC of vancomycin for the organism. Bacterial growth in biofilm was inversely related to vancomycin concentration in biofilm, but even extremely high drug concentrations did not eradicate bacteria embedded in biofilm. The MICs and MBCs for bacteria recovered from biofilm did not differ from those for incubating organisms. Thus, failure of glycopeptide antibiotics to cure prosthesis-related infection is not due to poor penetration of drugs into biofilm but likely due to diminished antimicrobial effect on bacteria in the biofilm environment.     

Thickness and grain size monitoring in seamless tube-making process using laser ultrasonics

The seamless tube-making process often causes wall-thickness variations generally in a helical pattern along the tube length. A laser-ultrasonic system installed immediately after the final operation in tube making provides process monitoring. Tube wall thickness and temperature measurements guide the mill adjustments to achieve the desired tolerances. Using the same ultrasonic signals, additional functionality provides the ability to measure the size of austenite grains. A signal processing approach based on a single echo analysis is used for determining wall thickness and austenitic grain size in relatively thick materials. Discussions review challenges specific to on-line conditions such as limited signal-to-noise ratio. A statistical comparison with metallographic results shows that the laser-ultrasonic grain sizes determined on-line have at least the same accuracy.     

Observer design for discrete systems with unknown exogenous inputs

A design procedure is developed for determining optimal discrete observers for estimating system states and unknown exogenous system inputs. This procedure is based on augmenting a standard system observer with an input model. The augmented model is then transformed into the discrete z-domain to determine relevant input/output transfer function matrices. The transfer function matrices are used to develop transfer function relationships between unknown exogenous inputs and the observer estimate of these inputs. It is shown that the optimal observer gains can be determined by implementing the observer as a Fisher filter. An example of the procedure is demonstrated with a third-order point-mass tracking filter