Selection of a drainage operation in obstruction of the common bile duct

Drainage operations were accomplished on extrahepatic bile ducts in 194 patients. It is the authors' opinion that in emergency surgery the operative procedure may be terminated by external drainage only in relative blockade of bile outflow in the duodenal lumen, while in unrelieved complete blockade of bile outflow such drainage seems to be permissible only in patients with an extremely high operative risk. Biliodigestive anastomoses were constructed in 96 patients. In persistant cholemia, cholangitis, signs of hepatic insufficiency the authors construct biliodigestive anastomoses and simultaneously accomplish provisional external drainage of bile ducts.     

Analysis of polymorphism of the hypervariable locus of the apolipoprotein-B gene in populations of the Volga-Ural region

Data on the allelic polymorphism at the hypervariable locus 3' to the apolipoprotein B gene (apo B) in seven Turkic and Finno-Ugric human populations of the Volga-Ural region obtained by means of PCR method are presented. Sixteen allelic variants were distinguished, and the frequency distribution of alleles and genotypes across the populations studied were estimated. Alleles 34 and 36 appeared to be more common (from 13 to 45% in different populations); the calculated heterozygosity indices ranged from 59.3 to 73.4%. Comparison of the data with that on other world populations made it possible to deduce some specific features of the alleles frequency distribution associated with geographic position of the population.