Fetal heart rate patterns in postasphyxiated fetal lambs with brain damage

OBJECTIVE: We previously showed that in asphyxiated fetal lambs the duration of hypotension correlated well with the severity of histologic damage to the brain, whereas the duration of bradycardia did not. This study compares fetal heart rate patterns with the degree of histologic damage to the brain. STUDY DESIGN: Twelve chronically instrumented near-term fetal lambs were subjected to asphyxia by umbilical cord occlusion until fetal arterial pH was <6. 9 and base excess was <-20 mEq/L. An additional 4 fetuses served as sham-asphyxia controls. Fetal heart rate (from electrocardiogram), arterial blood pressure, fetal breathing movements, and electrocorticogram were continuously monitored before, during, and for 72 hours after asphyxia. Fetal brain histologic features were categorized as mild (group 1, n = 5), moderate (group 2, n = 4), and severe (group 3, n = 3). Long-term fetal heart rate variability expressed as amplitude range was assessed visually every 5 minutes from 30 minutes before asphyxia until 2 hours of recovery and at 6, 12, 24, 48, and 72 hours of recovery. RESULTS: Long-term fetal heart rate variability amplitude decreased from 32 +/- 17 beats/min (mean +/- SEM) preocclusion to 4 +/- 13 beats/min at the end of occlusion (P <.001) without significant differences among the 3 groups. During 10 to 45 minutes of recovery, the long-term variability of group 1 was significantly greater than that of groups 2 and 3. At 24 to 72 hours of recovery, the long-term variability of groups 1 and 2 was significantly higher than that of group 3, which was almost 0. The "checkmark" and sinusoidal fetal heart rate patterns were observed during the recovery period in groups 2 and 3. CONCLUSIONS: Decreased long-term fetal heart rate variability and the "checkmark" and sinusoidal fetal heart rate patterns were indicators of the severity of asphyxial histologic damage in the fetal brain.     

A comparative evaluation of foreground/background sketch-based mesh segmentation algorithms

This paper presents an extensive comparative evaluation of five popular foreground/background sketch-based interactive mesh segmentation algorithms, addressing the quantitative assessment of the accuracy, efficiency, and stability of each algorithm. To facilitate the comparison, we have developed a complete framework with an intuitive and simple sketch-based interface to enable interactive mesh segmentation by marking strokes to specify the foreground and background with the mouse buttons, allowing us to quantify the algorithms in a unified manner. The evaluation has been performed via extensive user experiments in which each participant was assigned to segment models with the evaluated algorithms and the corresponding update of each segmentation was recorded as a new refinement when additional interactions were added. We then collected the segmentations from participants and evaluated them against the ground-truth corpus constructed from the Princeton segmentation database. To investigate how well the interactive segmentations match the ground-truth, five metrics were used to measure the boundary and region accuracy of segmentations. By studying the experimental results, we have analyzed the performance of the evaluated algorithms and provided valuable insights into their characteristics.     

Paint Mesh Cutting

We present a novel progressive painting‐based mesh cut out tool, called Paint Mesh Cutting, for interactive mesh segmentation. Different from the previous user interfaces, the user only needs to draw a single stroke on the foreground region and then obtains the desired cutting part at an interactive rate. Moreover, the user progressively paints the region of interest using a brush and has the instant feedback on cutting results as he/she drags the mouse. This is achieved by efficient local graph‐cut based optimizations based on the Gaussian mixture models (GMM) on the shape diameter function (SDF) metric of the shape. We demonstrate a number of various examples to illustrate the flexibility and applicability of our system and present a user study that supports the advantages of our user interface.     

嵌入式智能排泄系统的设计

介绍了一种基于AT89C52单片机嵌入式智能人工肛门的设计方案.这种智能人工肛门主要包括单片机控制模块、压力检测模块、超声检测模块和报警模块四部分.压力检测模块不断检测人工肛门肠腔内部的压力变化,并将信号传递给单片机.单片机处理来自压力检测模块的压力信号,当压力超出一定数值时,单片机启动超声检测模块.超声波发射模块发射超声波,并被肠壁另一侧的超声接收模块接收.超声波穿过肠腔内容物,将会产生一定的衰减,速度会发生变化.通过测量超声波经过肠腔内容物的时间,能够得到超声波通过肠腔内容物的平均速度,而超声波通过不同物体的速度是不同的,从而大致判断肠腔内容物的物理性质,为患者提供不同级别的警告信息.     

Diagnostic and therapeutic update on primary duodenogastric reflux

The authors, after some remarks on the pathophysiology of primary alkaline gastritis, analyze the main methods, available at present, for diagnosis; they particularly consider the importance of endoscopy and histology, gastroesophageal 24-hours pH-metry and 99mTc HIDA scintigraphy. Successively, they present the criteria for the identification of patients who will predictably benefit from surgical treatment, and examine advantages and limits of the two main corrective surgical techniques for the duodenogastric reflux in patients not previously operated on the gastrointestinal tract: duodenal extramucosal myotomy according to Mattioli, relatively easy to perform, and the "duodenal switch" according to De Meester, technically more complex, but pathophysiologically more acceptable, completely eliminating the duodenogastric reflux.     

Action of levorin on glucose transport in the rat small intestine

The technique of accumulating preparation of the mucosa and "turned out sac" was used to show that levorin, a polyenic antibiotic in a concentration of 10(-6) M, lowered the transport rate and accumulation of glucose by the epithelial cells of the rat thin intestine under conditions of oxygenation. Suppression of the glucose transport in the first stages resulted in partial inhibition of the transmembrane transfer. It is suggested that levorin suppression of the glucose transport through the erythrocyte apical membrane in the thin intestine is associated with a decrease in the electrochemical gradient of Na+.     

The effect of acebutolol on the cerebral circulation of man

The term dyshidrosis describes a nonspecific tissue pattern reaction characterized by a noninflammatory, pruritic (and sometimes burning) intraepidermal vesicular dermatosis involving selected areas of the fingers, palms, and soles. It should be distinguished from various pustular and vesicular dermatoses of the palms and soles with or without associated lesions elsewhere. When dyshidrotic lesions appear in areas where friction or pressure from the handling or wearing of sport gear occurs, the discomforting symptoms are noticeably accentuated and can thus interfere with the participant's effectiveness in the performance of the sport. A composite approach of dermatologic therapeutic acumen and physician-sponsored emotional support is essential in effectively handling this problem so that dyshidrosis does not "handicap" the patient.     

Improvement of YBCO Superconductor Magnetic Shielding by Using Multiple Bulks

HTS bulks present a high critical current density which can be used as magnetic shields. Previous works showed that BSCCO bulks can screen magnetic fields up to 0.1 T. For large scale applications like electrical machines, stronger magnetic field is usually needed. In so doing, (RE)BCO materials are more suitable since they can shield much higher magnetic fields. Another key issue concerns the size of the bulks. Nowadays, it is possible to manufacture 150-mm diameter class cylindrical YBCO bulk. In order to get larger magnetic shielding areas, multiple bulk superconductors should be arrayed and stacked in layers. This paper presents experimental results on screening performances of layered YBCO pellets. These results are compared with 2D simulations. The experiments are carried out at 77 K under external magnetic fields of 150 mT. Different topologies are considered: single-layer configuration with 9 square pellets and double-layer configuration with respectively 9 and 4 square pellets. Experimental and simulation results show that a checkerboard of one layer configuration does not fully shield the external magnetic field. Improved shielding properties are obtained when the double-layer configuration is used.     

潮湿褐煤干法分选实验研究

为提高空气重介质流化床对入料煤水分的适应性,以热气代替常温空气改善流化床对褐煤的分选效果。采用可能偏差Ep为评价指标,研究了热态空气重介质流化床的干燥温度、干燥时间和风量对褐煤分选效果的影响。结果表明:干燥温度为30~50℃时,干燥温度越高,Ep越低;干燥时间为1~5 min时,干燥时间越长,Ep越低,超过3 min后,Ep降低缓慢;风量为8~12 m3/h时,风量增大,Ep先降低后升高。煤样表面水分越高,干燥温度、干燥时间和风量变化对Ep影响越显著。表面水分1%的褐煤,干燥温度50℃、干燥时间5 min、风量10 m3/h时,褐煤分选效果最好,Ep可达到0.022g/cm3。实验证明热态空气重介质流化床可用于分选潮湿褐煤。     

基于一种高精度卷积神经网络的框架结构模型故障诊断研究

框架结构健康检测和故障诊断是机械工程和土木工程等学科中十分重要的科学问题,能够准确诊断出框架结构的故障是保证框架结构健康工作的基本前提.为了提高噪声条件下的框架结构故障诊断精度,对现有的 TICNN(convolution neural networks with training interference)模型进行了...