Prophylaxis of neurological manifestations of lumbar osteochondrosis: intermediate results, unsolved problems and some methodologic aspects

Issues of prophylaxis and rehabilitation are considered as regards neurologic manifestations of spinal osteochondrosis (NMSO). NMSO primary prophylaxis requires investigation and quantitative evaluation of the disease risk factors, epidemiologic determination of both incidence and prevalence in different groups of population in various periods of time. The standard risk group of NMSO in Byelorussian consists of population of 40-49-year-olds. Some professions may be risk factors for both onset and relapse of NMSO. Secondary prophylaxis of NMSO concerns elevated relapse risk, screening for individuals with either subclinic or early clinic manifestations of the disease. The computer screening-system has been created to identify a group at high risk of NMSO onset or relapse, to keep records, to print documents. It also gives chance to carry out individual prophylaxis of the high risk in the course of mass examination of employees.     

下一代IP网与第五代路由器

目前人们面临网络建设方向的选择，QoS、安全性和可信任性、IP网的可运营性等关键技术成为未来网络发展重点。下一代IP网络将采用IP网的核心技术。结合电信网的设计理念，建设一个可管理、可运营的网络，为运营商提供一个可以达到电信网服务质量保证的IP网，建立可赢利的商业模型。第五代路由器由于采用有智能的网络处理器(NP)，可以灵活加进对用户的管理等多种功能，完全适应下一代IP网的发展要求。     

The effect of mammalian anxiety factors on insects. The action of the corticoliberin 2-4 fragment on the behavior of the mealworm beetle Tenebrio molitor

The effect of the corticoliberin 2-4 fragment--tripeptide Pro-Pro-Ile (PPI) inducing increase in epileptiform activity of mammal on T. molitor males behaviour has been studied. The "open field" method modified for insects has been used. PPI in doses of 30, 60, 100, 1000 micrograms/kg was injected in hemolymph of the beetles. The horizontal activity (HA), number of turns (TN) and other parameters were registered during 6 min. The tripeptide in dose 30 micrograms/kg was non-effective. PPI in doses 100 and, especially, 1000 micrograms/kg evoked stable decrease in HA that was observed as early as 0.5 h after injection. This effect lasted throughout 4-24 hrs and, apparently, induced by nonspecific action of high doses of the peptide. PPI in dose 60 micrograms/kg produced the significant intensification of stressogenic influence of experimental situation: in 2-4 hrs after injection the level of HA and TN increased. It is suggested that PPI can be regarded as an anxiogenic factor of insects.     

Optimization of the scintigraphic segmental anatomy of the lungs

Accurate and reproducible reporting of lung scintigraphy is predicated on a sound knowledge of the segmental anatomy of the lungs. A limited amount of hard data exists about the true segmental anatomy of the lungs. A virtual model of human lungs was created using a CT-based dataset and a Monte Carlo simulation technique to examine the optimal projections for the visualization of each segment in the lungs. METHODS: Segmental anatomy of the lungs was modeled using CT, cadaveric lungs and standard anatomical texts. The emission, scatter and attenuation of photons was modeled within these virtual lungs and the surrounding tissues. Single segmental lesions were created in eight projections and submitted for blinded reporting to four experienced nuclear medicine physicians to obtain the best views for each segment. RESULTS: The anterior and posterior oblique projections yielded the best views for 10 of 18 segments, with the laterals contributing four views, the anterior contributing two views and the posterior contributing one view. The majority of basal segments (six of nine) were best seen in the anterior and posterior oblique projections. CONCLUSION: This model overcomes the major problems associated with experimentation in the normal human and has the potential to provide answers to the major problems of scatter, attenuation and "shine-through" in lung scintigraphy.     

Ploidy and liquid-holding recovery in yeasts sensitive to radiation and nitrous acid

The effects of genome ploidy and posttreatment incubation on inactivation by nitrous acid (NA) were studied in normal, radio- and nitrous acid-sensitive strains of yeast. In normal yeast cells the increase of ploidy (haploid to triploid) resulted in "the protective effect", i.e. haploid cells were the most sensitive, triploid -- the most resistant. This "protective effect" is absent in polyploid yeast homozygous for the xrs1-5 (rad 54) mutation; in this case the NA-sensitivity rises with the increase of ploidy, i.e. haploid cells are the most resistant ones. The effect of liquid holding (LH) after the NA treatment depends on the genetic background and ploidy of treated cells. Posttreatment incubation in buffer has practically no effect on the survival of wild-type Berkeley's yeast strains (1n, 2n, 3n). The highly homozygous haploid strains from Zakharov' collection, both wild type and xrs1-5 mutant, exhibit no LH-recovery too. However the death of wild-type cells drastically rises in LH-condition as the ploidy increases. 24 hours incubation in buffer results in at least a ten-fold decrease in survival of wild type 2n, 3n, 4n cells. The loss of viability is proportional to the time of incubation, but the cell titer being constant. The strains (2n, 3n, 4n) homozygous for the xrs1-5 mutation (rad 54) show considerable LH-recovery. It is supposed that the xrs1-5 mutation results in the derepression of the prereplicative pathway of LH-recovery which eliminates the NA-INDUCED DAMAGE OF DNA.     

两强竞争市场中的企业广告策略分析

将Dawid和Feichtinger的混沌型的广告扩散型扩展到两强竞争的市场环境下，为检验模型的可用性开发了一个计算机仿真系统，仿真的结果表明在两强竞争下的企业最好的广告策略是增加广告投入直到达到“双赢状态”，即市场占有率的振荡即将发生的临界状态，分析应用结果表明提出的混沌型模型和开发的仿真系统为市场竞争环境下的企业广告策略的分析和制定提供了一个有效的工具。     

ERP软件中的组织结构与BPR的实现

以SAP R／3为例，讨论了企业资源计划软件中组织结构框架，指出了该软件中的组织构架是按功能设立的，各个不同功能有自己的组织结构，各个不同模块有自己的权力控制设置，这是一个虚体企业的结构。企业资源计划软件在企业的实施，可以按企业的虚体和实体的映射实现业务过程重构。本文最后给出一个观点，即企业虚体结构的优化也是业务过程重构的一种形式，参考企业资源计划软件的模型，有助于系统低风险、快速地实施。