Response of human epithelial cells to culture surfaces with varied roughnesses prepared by immobilizing dendrimers with/without D-glucose display

To investigate the response of human epithelial cells to substrates with nanoscale modifications, dendrimer-immobilized surfaces were prepared with or without D-glucose displayed as a terminal ligand, giving topographic structures with mean roughnesses (R(a)) of 1.8-11.0 nm. With an increase in the R(a) value up to 4.0 nm, the epithelial cells cultured on naked dendrimer surface without D-glucose display were somewhat stretched in their morphology compared with those on a nonmodified plain surface. However, for the R(a) values higher than 4.0 nm, such cell stretching was inhibited, resulting in the predominant existence of round-shaped cells. The change in cell morphology was appreciable on the surfaces with D-glucose-displayed dendrimers. When the R(a) value increased up to 4.5 nm on these surfaces, in particular, the enhancement of cell stretching was recognized, and fluorescence microscopic observation supported the hypothesis that the glucose-transporter-mediated adhesion of cells to the surface encouraged the development of filopodia and stress fibers, thereby improving focal contact with the surface. Our results suggest that the combination of displaying D-glucose and modulating roughness can promote cytoskeletal formation accompanied by marked cell elongation on culture surfaces.     

Co41Ni33Al26合金的再结晶、马氏体相变和铁磁特性

研究了Co41Ni33Al26铁磁性形状记忆合金的再结晶行为和组织变化规律,采用振动磁力计（VSM）和示差热分析仪（DSC）分析了合金磁性和马氏体相变特点。结果表明,经43．65％的大压下量冷轧变形的Co41Ni33Al26合金在低于1000℃发生再结晶,随着淬火温度的升高,合金中β相体积分数不断增加。冷轧组织中在β／γ相界面上有很多微裂纹,这是由于两相变形不协调而形成的,微裂纹的形成有利于合金的塑性变形,在高于1200℃处理时微裂纹消失,表现出“自愈合”能力。该合金的马氏体相变温度和居里点都随着淬火温度的升高而升高,居里点始终高于马氏体相变温度,且马氏体相的磁晶各向异性高于β母相的,说明该合金是很好的铁磁性形状记忆合金的候选材料。     

Ni40.5Co32.5Al27合金冷轧带材阻尼性能与相变和组织的关系

对Ni40.5Co32.5Al27合金带材进行三种热处理,分析了不同试样的显微组织,采用微分差热分析测定了马氏体转变温度,用动态热机械谱仪研究了相变及阻尼性能.结果表明经过1 623K×5 h直接水冷获得基体相为竹节状粗大再结晶晶粒;而慢冷(0.5 K/min)到1 273 K后水冷时析出粗大γ相,快冷(10 K/min)至1 273 K再水冷则析出较均匀细小的γ相.降温过程中合金带材在马氏体相变区出现阻尼峰,并且阻尼峰随频率降低而升高;马氏体相变结束后,合金带材的阻尼性能随温度降低而继续升高;合金带材的阻尼性能随γ相粗化而增强,并且室温附近超过0.04,有望成为新型阻尼材料.     

Thermal Stability of Low-SiC Fiber (Hi-Nicalon) Treated in a Hot Isostatic Press

The low-oxygen SiC fiber fabricated by the electron-beam irradiation curing method, Hi-Nicalon, was heated at 1773 to 2273 K in a hot isostatic press (800 MPa of argon) and was subsequently reheated at 1873 K at 1 atm (101 kPa) of argon. The hot isostatic press treatment delayed the onset of fiber deterioration to higher temperature. The fiber strength remained almost unchanged by subsequent reheating at 1873 K in 101 kPa of argon. The thermal stability of Hi-Nicalon, as a consequence of the permanent change in surface structure, can be greatly improved by treating in the hot isostatic press.     

A Safety Mechanism Using Software Patterns

Software patterns have been widely studied in order to reuse of design knowledge in software design phase. However, few patterns have been known in the area of safety. This paper addresses a mechanism for safety and its software pattern in a reactive system. We construct a pattern composed of a mechanism called an event checker including several software patterns to check scenarios, i.e., the order of events and their timing constraints. Next, we show examples of its implementation to railroad models using Java. Moreover, we discuss the safety in the domain of a reactive system by means of this event checker and its software reliability by using this pattern.