The influence of polymer blend composition on the degradation of polymer/hydroxyapatite biomaterials

The in vitro degradation of biodegradable polymer/ceramic composites was assessed in two different environments under both static and pseudodynamic conditions. The blends, consisting of polycaprolactone, poly(lactic-co-glycolic acid), and hydroxyapatite, have potential use in bone tissue engineering applications, thus it is essential to establish a standardized method of characterizing the degradation of new biomaterials. In this study, the variation in polymer blend ratio was examined to observe a change in degradation rate. The porous blends were degraded in water and serum-containing media. A previous study examined in vitro degradation in serum-free buffer. Molecular weight loss, gravimetric weight loss, pH changes and morphological changes were evaluated. The changes in porosity were observed with scanning electron microscopy and quantitatively assessed using image analysis. There was a significant difference in molecular weight loss and gravimetric weight loss between the blends after 10 weeks in vitro. Blends containing the greatest amount of poly(lactic-co-glycolic acid) degraded most rapidly. © 2001 Kluwer Academic Publishers     

DV旅游基本拍摄技巧

相比数码相机,数码摄像机强大的动态拍摄决不是普通的数码相机动态拍摄功能简单格式的提高所能取代的。虽然家用数码摄像机的使用比数码相机来得容易,轻轻操作几个按钮就可以实现拍摄,但很多朋友并没有领会到DV拍摄的实质,以至于外出旅游时,因为使用经验不足所造成的画面效果不理想,浪费了难得的旅游机会和美好时刻。为了更好地帮助大家掌握好旅游时DV的拍摄效果,本文特将笔者多年的DV使用经验编辑成快速入门指南,以期能给携带DV外出旅游的人们提供一些有益的参考。三个基本功一定要注意基本功是DV拍摄入门的重要基础,这三个基本功看上…     

Layer 1 virtual private network management by users

The layer 1 virtual private network (LlVPN) technology supports multiple user networks over a common carrier transport network. Emerging L1VPN services allow: L1VPNs to be built over multiple carrier networks; L1VPNs to lease or trade resources with each other; and users to reconfigure an L1VPN topology, and add or remove bandwidth. The trend is to offer increased flexibility and provide management functions as close to users as possible, while maintaining proper resource access right control. In this article two aspects of the L1VPN service and management architectures are discussed: management of carrier network partitions for L1VPNs, and L1VPN management by users. We present the carrier network partitioning at the network element (NE) and L1VPN levels. As an example, a transaction language one (TL1) proxy is developed to achieve carrier network partitioning at the NE level. The TL1 proxy is implemented without any modifications to the existing NE management system. On top of the TL1 proxy, a Web services (WS)-based L1VPN management tool is implemented. Carriers use the tool to partition resources at the L1VPN level by assigning resources, together with the WS-based management services for the resources, to L1VPNs. L1VPN administrators use the tool to receive resource partitions from multiple carriers and partner L1VPNs. Further resource partitioning or regrouping can be conducted on the received resources, and leasing or trading resources with partner LlVPNs is supported. These services offer a potential business model for a physical network broker. After the L1VPN administrators compose the use scenarios of resources, and make the use scenarios available to the L1VPN end users as WS, the end users reconfigure the L1VPN without intervention from the administrator. The tool accomplishes LlVPN management by users     

Complex Permittivity of Liquid and Granular Materials Using Waveguide Cells

The four boundary cell is an important arrangement for the measurement of complex permittivity of bulk solids and liquids. Transcendental equations for reflection and transmission are derived and previous errors in the literature are noted. This measurement method is extended to granular samples where a compression technique is introduced to minimize the dispersion in S-parameter measurements associated with interface problems.     

Reliability of DSM-IV anxiety and mood disorders: Implications for the classification of emotional disorders.

The reliability of current and lifetime Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV; American Psychiatric Association, 1994) anxiety and mood disorders was examined in 362 outpatients who underwent 2 independent administrations of the Anxiety Disorders Interview Schedule for DSM-IV: Lifetime version (ADIS-IV–L). Good to excellent reliability was obtained for the majority of DSM-IV categories. For many disorders, a common source of unreliability was disagreements on whether constituent symptoms were sufficient in number, severity, or duration to meet DSM-IV diagnostic criteria. These analyses also highlighted potential boundary problems for some disorders (e.g., generalized anxiety disorder and major depressive disorder). Analyses of ADIS-IV–L clinical ratings (0–8 scales) indicated favorable interrater agreement for the dimensional features of DSM-IV anxiety and mood disorders. The findings are discussed in regard to their implications for the classification of emotional disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A fuzzy logic classification scheme for selecting and blendingsatellite ocean color algorithms

An approach for selecting and blending bio-optical algorithms is demonstrated using an ocean color satellite image of the northwest Atlantic shelf. This approach is based on a fuzzy logic classification scheme applied to the satellite-derived water-leaving radiance data, and it is used to select and blend class-specific algorithms. Local in situ bio-optical data were used to characterize optically-distinct water classes a priori and to parameterize algorithms for each class. Although the algorithms can be of any type (empirical or analytical), this demonstration involves class-specific semi-analytic algorithms, which are the inverse of a radiance model. The semi-analytic algorithms retrieve three variables related to the concentrations of optically active constituents. When applied to a satellite image, the fuzzy logic approach involves three steps. First, a membership function is computed for each pixel and each class. This membership function expresses the likelihood that the measured radiance belongs to a class, with a known reflectance distribution. Thus, for each pixel, class memberships are assigned to the predetermined classes on the basis of the derived membership functions. Second, three variables are retrieved from each of the class-specific algorithms for which the pixel has membership. Third, the class memberships are used to weight the class specific retrievals to obtain a final blended retrieval for each pixel. This approach allows for graded transitions between water types, and blends separately tuned algorithms for different water masses without suffering from the “patchwork quilt” effect associated with hard-classification schemes     

Supporting service differentiation in wireless packet networksusing distributed control

This paper investigates differentiated services in wireless packet networks using a fully distributed approach that supports service differentiation, radio monitoring, and admission control. While our proposal is generally applicable to distributed wireless access schemes, we design, implement, and evaluate our framework within the context of existing wireless technology. Service differentiation is based on the IEEE 802.11 distributed coordination function (DCF) originally designed to support best-effort data services. We analyze the delay experienced by a mobile host implementing the IEEE 802.11 DCF and derive a closed-form formula. We then extend the DCF to provide service differentiation for delay-sensitive and best-effort traffic based on the results from the analysis. Two distributed estimation algorithms are proposed. These algorithms are evaluated using simulation, analysis, and experimentation. A virtual MAC (VMAC) algorithm passively monitors the radio channel and estimates locally achievable service levels. The VMAC estimates key MAC level statistics related to service quality such as delay, delay variation, packet collision, and packet loss. We show the efficiency of the VMAC algorithm through simulation and consider significantly overlapping cells and highly bursty traffic mixes. In addition, we implement and evaluate the VMAC in an experimental differentiated services wireless testbed. A virtual source (VS) algorithm utilizes the VMAC to estimate application-level service quality. The VS allows application parameters to be tuned in response to dynamic channel conditions based on “virtual delay curves.” We demonstrate through simulation that when these distributed victual algorithms are applied to the admission control of the radio channel then a globally stable state can be maintained without the need for complex centralized radio resource management     

Influence of casting technique and hot isostatic pressing on the fatigue of an Al-7Si-Mg alloy

The influence of the casting filling technique and hot isostatic pressing (hipping) on the fatigue-life distribution of Al-7Si-Mg alloy castings has been studied. To vary the number density and size of oxide-film defects in the castings, test bars were cast using bottom-gated filling systems with and without filtration. Some unfiltered castings were subjected to a hipping treatment of 100 MPa at 500 °C for 6 hours. Test pieces were machined from the castings and were fatigue tested in pull-pull sinusoidal loading, at maximum stresses of 150 and 240 MPa under a stress ratio of R=+0.1. The fatigue lives at any probability of failure and Weibull statistical parameters of the filtered castings were higher than those of the unfiltered and nonhipped castings, illustrating the importance of the casting technique. However, the unfiltered but hipped castings exhibited higher performance. It is proposed that the significant improvement in fatigue life after hipping is due to the deactivation of entrained double oxide-film defects as fatigue-crack initiators.     

Mixed-mode, high-cycle fatigue-crack-growth thresholds in Ti-6Al-4V: Role of bimodal and lamellar microstructures

Mixed-mode, high-cycle fatigue-crack growth thresholds are reported for through-thickness cracks (large compared to microstructural dimensions) in a Ti-6Al-4V turbine blade alloy in both lamellar and bimodal microstructural conditions. Specifically, the effect of combined mode I and mode II loading, over a range of phase angles (β=tan ⁻¹ (ΔK _II/ΔK _I) from 0 to 62 deg (ΔK _II/ΔK _I∼0 to 1.9), is examined at a load ratio (ratio of minimum to maximum loads) of R = 0.1 and a cyclic loading frequency of 1000 Hz in ambient-temperature air. When the mixed-mode, crack-driving force is characterized in terms of the strain-energy release rate (ΔG), incorporating contributions from both the applied tensile and shear loading, the threshold for fatigue-crack growth is observed to increase significantly with the applied mode-mixity (ΔK _II/ΔK _I) for both microstructures, an effect attributed to enhanced crack-tip shielding. The pure mode I threshold, in terms of ΔG _TH, is observed to be a lower bound (worst case) with respect to mixed-mode (I + II) behavior. For large crack sizes, the threshold fatigue-crack growth resistance of the lamellar structure is observed to be superior to that of the bimodal material for all phase angles investigated. Consideration of mode I fatigue-crack growth thresholds for small cracks in these same microstructures suggests that this rank ordering of mixed-mode fatigue resistance may not hold for crack lengths that are comparable to microstructural size scales. Examination of the fatigue-crack wake indicates that, for the lamellar microstructure, the path of crack extension is significantly influenced by the local microstructure over length scales on the order of the relatively coarse lamellar colonies (∼500 μm). Comparatively, the crack path in the bimodal material is more strongly influenced by the applied crack-driving force. This disparity in behavior is attributed primarily to the relatively heterogeneous crack-growth resistance of the coarse lamellar microstructure.     

Long-term trends in accumulated metals (Cd, Cu and Zn) and metallothionein in bivalves from lakes within a smelter-impacted region

Temporal monitoring studies are needed to detect long-term trends in ecosystem health. In the present study, we tested metallothionein (MT) as a potential biomarker for long-term variations in trace metal levels in lakes subject to atmospheric metal inputs from a nearby copper smelter. Over a 13-year period, we estimated on several occasions ambient free Cd2+, Cu2+ and Zn2+ concentrations at the sediment-water interface in six lakes with contrasting metal levels, and measured metal and metallothionein concentrations in gills of bivalves (Pyganodon grandis) living in these lakes. All but one of the study lakes had comparable drainage ratios, so inter-lake differences in hydrological export of metals from contaminated watersheds to receiving waters were likely minimal. Declines in the metal emissions from the smelter (especially for Cd and Zn) during the 1980s led to appreciable decreases in both calculated free Cd2+ ion concentrations in the study lakes (-59+/-21% between 1989 and 1998) and accumulated Cd levels in their clam populations (-46+/-12% between 1989 and 2002). Taking all lakes into account, MT concentrations in bivalves have comparatively dropped by 44% (+/-10%) since 1989. In contrast to what we found for Cd, there were no significant reductions in the calculated free Cu2+ and Zn2+ concentrations in the various lakes during our study period (-2 and -10%, respectively, with 95% confidence intervals spanning zero). Overall, observed decreases in MT in bivalves over time were best correlated with similar decreases in both ambient and accumulated Cd levels (r = 0.77, P = 0.0003 and r = 0.79, P < 0.0001, respectively, both P-values corrected for temporal autocorrelation), suggesting that long-term trends in gill MT concentrations in P. grandis may be useful as predictors of temporal changes in environmental Cd contamination in lakes.