The current status and developmental paths of surgical gynecology

The article is devoted to actual problems of operative gynecology. Modern advantages in endoscopic, microsurgical, reconstructive-plastic surgery in gynecology are shown. Further improvement of the urogynecological operative technique remains to be an important task. The authors believe that the future belongs to organ-saving operations.     

A comparative analysis of the immediate and late results of coronary balloon angioplasty in bifurcation stenoses performed by the traditional method and by the "2-guide" method

The generation in plasma the anodic autoprecipitating protein, or autoprecipitin (AAP), as the bioincompatibility reaction under influence of a number of alien components during cardiac operations with using cardiopulmonary bypass, heterotopic vascular autotransplants and artificial valve implants was studied in 257 patients. Selective formation of the AAPs in result of their inductors effect was discovered by the methods of immunodiffusion and immunoelectrophoresis in blood of patients within operation periods and early postoperation hours. Repeated and reiterated generation of the AAPs due to bioincompatibility in patients with coronarosclerosis and endocarditis, undergoing prosthetic cardiac operations may favour developing reaction of immediate hypersensitivity with complications and has prognostic value.     

Prooxidant link of oxidative homeostasis under low doses of ionizing radiation of low intensity

Peculiarities of the processes of lipids peroxidation under effect of ionizing radiation in small doses and its low intensity have been considered. Data from literature concerning the threshold doses of lipids peroxidation activation have been generalized.     

Patterns in the shaping and realization of individual experience

This article describes the methodological approach of systemic psychology. In the framework of this approach a wide range of experimental data is analyzed: results of neuronal recordings in vitro and in awake normal and pathological animals learning to perform and performing both complex instrumental and simple behavioral acts. Another block of analyzed data is based on the experiments with human subjects that learn and perform the tasks of categorization of words and operator tasks, subjects, performing group game activity and answering the questionnaires of psychodiagnostic methods. As a result of this analysis, the system psychology approach is used to describe qualitatively and quantitatively the formation and realization of individual experience.     

Determination of likelihood of the development of pleural empyema in patients with cancer after pneumonectomy

Management of 150 patients with lung cancer after pneumonectomy has shown that the basic factors causing the onset of postoperative pleural empyema are chronic nonspecific pulmonary diseases, pronounced obstructive syndrome and right heart overload, tumor histology, local tumor size and cancer complications, duration and techniques of surgery, duration of controlled lung ventilation, as well as the onset of postoperative suppurative tracheobronchitis and surgical wound suppuration. The likelihood of empyema development may be assessed only upon analysis of the combination of risk factors with reference to their low informative value, preoperative patients' condition and intraoperative factors which have an equal impact on the onset of this complication. The efficacy of the algorithm elaborated is as follows: if the likelihood of empyema development exceeds 50%, it occurs in 96.3% of cases, if the likelihood of the complication is less than 10%, the postoperative period is uncomplicated in 87.8% of patients.     

The status of and ways to improve the reproductive health of servicewomen

In higher education, faculty advancement is based on demonstrated productivity in scholarship and service as well as teaching. In nursing, these expectations, added to clinical obligations, can make new faculty feel overwhelmed. The author recommends that new faculty take responsibility for their professional development by working with a dean or department chair to design a 5-year Faculty Development Plan that includes mentoring and participating in other campus support networks.     

Central hemodynamics in rats with various resistivity to acute hemorrhage

OBJECTIVE AND DESIGN: Effects of hyperimmune milk factor (HIMF), an anti-inflammatory factor from milk of hyperimmunised cows, on tight junction permeability and cell growth were studied in vitro. MATERIAL OR SUBJECTS: Mammary (HC11) and kidney (MDCK) epithelial cell lines were used. TREATMENT: HIMF was used at a final concentration of 2 mg/ml. METHODS: Tight junction permeability was assessed by measuring transepithelial electrical resistance (TER) across confluent monolayers, following the addition of HIMF with or without an inflammatory challenge. Cell growth was assessed by measuring total DNA of cultures with and without HIMF. Data were analysed by analyses of variance. RESULTS: HIMF promoted tight junction formation and prevented loss of TER following a challenge in both epithelia. Post-challenge recovery of TER was also faster with HIMF. HIMF inhibited cell growth. CONCLUSIONS: HIMF stimulates tight junction maintenance and formation, and its previously reported anti-inflammatory properties may be mediated by restricting the extravasation of white blood cells through tight junctions.     

Novel site-specific endonucleases from Brevibacterium species

New site-specific endonucleases BecAI and BecAII have been detected in Brevibacterium species A. Endonuclease BecAII free from contaminating nonspecific endonucleases, exonucleases, and phosphatases was isolated by column chromatography on phosphocellulose, heparin sepharose, and DNA cellulose. It recognizes and cleaves the 5'-GG decreases CC-3' sequence and is a true isoschizomer of HaeIII restriction enzyme. The other restriction endonuclease, BecAI, cleaves Ad2 DNA at least by 2 sites but not the DNA of phage lambda, T7, SV40, phiX174, and plasmides pBR322 and pUC19. The substrate specificity of BecAI indicates its appurtenance to the super rare restriction endonucleases.