Assessing obesity: classification and epidemiology

Obesity is generally defined as a body mass index (BMI) of 30 kg/m2 and higher. Overweight is defined as a BMI between 25 and 30 kg/m2. The prevalence varies considerably between countries, and between regions within countries. It is estimated that more than half of adults aged 35-65 living in Europe are either overweight or obese. Overweight is more common among men than among women but obesity is more common among women. The prevalence of obesity in Europe is probably in the order of 10-20% in men and 15-25% in adult women. In most European countries who have reliable data on time-trends the prevalence of obesity seems to be increasing. In most European countries, obesity is usually inversely associated with socio-economic status, particularly among women. New classifications of overweight may be based on cut-off points for simple anthropometric measures which reflects both total adiposity as well as abdominal fatness.     

Hepatectomy with hypothermic perfusion of the liver

Whereas most liver resections can be performed within 60 min, the period of vascular clamping and resulting ischemia may prove too short to allow complex major liver resections (MLR) especially on diseased livers. To overcome this problem, cooling of the liver with 4 degrees C preservations solution routinely used in liver transplantation may be used in three different approaches to MLR: I "In situ": the liver remains in the abdomen and integrity of afferent and efferent vessels is conserved. II "Ex situ-in vivo": the liver exteriorized from the abdomen by transecting all hepatic veins, remains connected to the porta hepatis. III "Ex vivo": the liver being removed from the abdomen, the MLR is performed extracorporeally. Of 15 MLR reported here, 11 were performed "in situ" and 4 "ex situ-in vivo"/Nowadays, the liver surgeon's "toolbox" must contain hypothermic liver perfusion. In carefully selected cases, these techniques allow MLR on diseases livers or mandating complex vascular procedures.     

Transduction properties of tracheal stretch receptors

1. Using single fibre vagal afferent recording, we have studied the behavior of slowly adapting stretch receptors located in an isolated, in situ, segment of the trachea in dogs. Responses to positive and negative steady and oscillating transmural pressures were investigated. 2. Seventy-eight per cent of the receptors studied were tonically active at resting tracheal volume. Ninety per cent showed a more pronounced response to positive than to negative transmural pressures. 3. During pressure oscillations the majority of the receptors had a higher discharge frequency at any given pressure during the ascending phase of the pressure wave than at the same pressure under static conditions. During most of the ensuing descent of pressure toward zero the discharge frequency led transmural pressure. 4. With increasing frequency of oscillation the differences from the static responses increased (dP/dt sensitivity), especially during the ascending limb of the pressure oscillation (rectifying behavior). 5. In a small number of receptors, discharge frequency lagged behind transmural pressure or was in phase with it ("no loop" pattern). 6. In three cases the same receptor exhibited dP/dt sensitivity during positive pressure oscillations, whereas discharge frequency lagged behind pressure during negative pressure oscillations. This indicates that the lack of dP/dt sensitivity exhibited under negative pressure conditions does not represent an intrinsic property of these receptors, but reflects some aspect of their mechanical arrangement within the airway wall. 7. THESE PATTERNS OF RESPONSE ARE DISCUSSed in terms of intrinsic and extrinsic characteristics of the receptors. 8. The physiological implications of stretch receptor behaviour are also considered.     

SiC半导体技术--即将腾飞的新一代半导体技术

电源设计者们仿佛正在目睹一个新的半导体技术的诞生。随之而来的新一代功率半导体器件远远优于现有的硅技术。SiC 材料可以让器件具有迄今为止设计工程师们梦寐以求却不能得到的出色特性。其最重要的优点包括以下几个方面：:工作结温高达225 ℃，而相应的漏电流只有适度的增加。由于本质上不会出现热偏移thermal run－away)，故可以在 很高的结温下可靠的工作。 没有正向或反向恢复，故即使在高温 下以高频工作时，也没有开关损耗。 甚至可以实现开关损耗极小、频率 高达1 M H z 的深度切换(h a rd 正向电阻具有…     

Impurity local phonon nonradiative quenching of Yb3+fluorescence in ytterbium-doped silicate glasses

We have studied the concentration quenching of Yb³⁺ ion fluorescence in Yb-doped silicate glasses containing up to 3.4×10 ²¹ cm^-3 Yb³⁺ ions. The absorption and fluorescence spectra are similar to those obtained for the Yb³⁺ ion in many different matrices, with a radiative lifetime of approximately 1400 μs. The fluorescence decay curves were different among samples, with strong dependence on the Yb concentration. The decay curves could always be resolved into two exponential components, indicating that the ions reside in two different sites, each of a different characteristic nonradiative decay mechanism. The fast decay times ranged between 6 and 300 μs, and the slow ones ranged between 190 and 1250 μs in different samples. The sites where ions exhibit the fast decay most probably consist of pairs of Yb³⁺ ions. The nonradiative decay probabilities for each site mere directly proportional to the Yb³⁺ concentration in the same site. We propose that the fluorescence quenching occurs by multiphonon nonradiative transitions involving polar local phonon bands created by the presence of the Yb³⁺ ion     

Iterative principal axes registration method for analysis of MR-PETbrain images

Computerized automatic registration of MR-PET images of the brain is of significant interest for multimodality brain image analysis. Here, the authors discuss the principal axes transformation for registration of three-dimensional MR and PET images. A new brain phantom designed to test MR-PET registration accuracy determines that the principal axes registration (PAR) method is accurate to within an average of 1.37 mm with a standard deviation of 0.78 mm. Often the PET scans are not complete in the sense that the PET volume does not match the respective MR volume. The authors have developed an iterative PAR (IPAR) algorithm for such cases. Partial volumes of PET can be accurately registered to the complete MR volume using the new iterative algorithm. The quantitative and qualitative analyses of MR-PET image registration are presented and discussed. Results show that the new PAR algorithm is accurate and practical in MR-PET correlation studies     

The relationship between dual mode cavity cross-coupling andwaveguide polarizers

Cross-coupling in dual-mode cavity filters may be obtained by introducing an asymmetry within the cavity cross section at an angle of 45° to the two orthogonal modes. This paper presents a novel formula relating the resulting cross coupling coefficient between the orthogonal resonances to the polarization of a waveguide polarizer. Previous theories for such polarizers may then be applied directly to the dual mode filter situation. Formulas enabling the dimensions of the asymmetries for required coupling coefficients are presented for square and circular waveguide cross sections     

坚不可催的病毒防护

我们都看过一部或两部关于僵尸的电影。某些医疗或化学事故创造出第一个，然后是一批，然后是成千上万几乎不可摧毁的无意识生物。除为剧情上的相似以外，大多数僵尸电影中常见的一个共同点是都有这样的情景。其中一个即将成为僵尸的受害者遇到一个僵尸，这个僵尸是以前一个亲爱的人变成的，因此这个人想“我们亲密的关系和信任所具有的力量可以保护我”，于是没有逃跑或进行防卫。结果是他被变成了另一具僵尸。