改良可逆性局灶性脑缺血模型建立

目的改良大鼠可逆性大脑中动脉缺血模型的栓子制作方法,增加模型稳定性和成功率,提高脑缺血实验研究结果的可靠性.方法体重280～320g Wistar雄性大鼠60只,随机分成改良组和对照组,每组30只.对照组用尼龙线一端加热法制作传统栓子,改良组用尼龙线一端沾silicone胶法制作改良栓子.两组模型除栓子制作方法不同外,其他手术步骤完全相同.采用Zea Longa 5分制法进行模型的神经功能评分,采用TTC染色法测量并计算梗死灶的大小.比较两组模型制作成功率、成功模型中神经功能评分3、4级大鼠所占百分数,以     

应力、强度呈非正态分布时可靠度公式的推导

介绍一种当应力、强度呈非正态分布时的可靠度的计算方法,以用来进行机械可靠性设计,并以一个地震载荷的直立压力容器为例加以说明。     

崇礼东坪黄金公司缓倾斜薄矿体采空区综合治理

在采空区调查的基础上,以FLAC工程力学分析软件为手段,应用“诱导崩落和封闭采空区综合治理”理论,进行缓倾斜薄矿体采空区综合治理研究.该项研究与实践为缓薄矿体采空区综合治理提供了可供借鉴的经验,并为矿山创造了可观的经济效益.     

The effectiveness of modified ingram therapy compared with severity of psoriasis

PURPOSE: This study investigated the pathogenesis of tractional retinal detachment associated with proliferative vitreoretinopathy in an experimental model, using immunohistochemical staining. METHODS: To produce tractional retinal detachment in rabbit eyes, homologous cultured fibroblasts obtained from the gluteal muscle fascia were injected intravitreously. Right eyes of 20 rabbits in the study group, and 7 rabbits in the control group were followed for 26 days at weekly intervals with indirect ophthalmoscopy and fundus photographs. RESULTS: During the follow-up period grade III tractional retinal detachment developed in 11 eyes, grade II in six, and grade 1 in three eyes. The spindle-shaped cells contributed predominantly to the development of epiretinal membrane, and a smaller number of round small and large cells. In 10/17 grade II and III eyes, spindle-shaped cells had vimentin, 7/10 had actin, 5/17 had GFAP, 4/17 had S-100 protein immunoreactivity. Round small and large cells expressed S-100 protein, GFAP and actin in 5/17 eyes. Epiretinal membrane appeared to be formed by spindle-shaped fibroblast-like cells and small and large round glia-like cells. Actin positivity of spindle-shaped and round cells was taken as a marker of contractile elements of the cells and their locomotional features. CONCLUSIONS: These features are believed to be involved in contraction of the membrane and retinal detachment.     

Allelotype analysis of uterine leiomyoma: localization of a potential tumor suppressor gene to a 4-cM region of chromosome 7q

The degree and nature of patient involvement in consultations with health professionals influences problem and needs recognition and management, and public accountability. This paper suggests a framework for understanding the scope for patient involvement in such consultations. Patients are defined as co-producers of formal health services, whose potential for involvement in consultations depends on their personal rights, responsibilities and preferences. Patients' rights in consultations are poorly defined and, in the National Health Service (NHS), not legally enforceable. The responsibilities of patients are also undefined. I suggest that these are not to deny, of their own volition, the rights of others, which in consultations necessitate mutuality of involvement through information-exchange and shared decision-making. Preferences should be met insofar as they do not militate against responsibilities and rights.     

Complementary therapies for depression: an overview

Depression is one of the most common reasons for using complementary and alternative therapies. The aim of this article is to provide an overview of the evidence available on the treatment of depression with complementary therapies. Systematic literature searches were performed using several databases, reference list searching, and inquiry to colleagues. Data extraction followed a predefined protocol. The amount of rigorous scientific data to support the efficacy of complementary therapies in the treatment of depression is extremely limited. The areas with the most evidence for beneficial effects are exercise, herbal therapy (Hypericum perforatum), and, to a lesser extent, acupuncture and relaxation therapies. There is a need for further research involving randomized controlled trials into the efficacy of complementary and alternative therapies in the treatment of depression.     

Revitalization of the Warren G. Magnuson Clinical Center at the National Institutes of Health

This article is based on research into patients' perceptions of being in hospital. Time, ordinarily taken for granted, becomes a significant problem for people in hospital. Patients seek control over time that they do not seem to have during their stay in hospital. They try to keep track of time and find ways of passing it, while believing that precious personal time is lost to them. The insight gained into differing perceptions of time and how patients coped with these can be used to reduce some of the tensions and negative aspects of the way time is experienced in hospital.