全文获取类型
收费全文 | 35922篇 |
免费 | 2090篇 |
国内免费 | 26篇 |
专业分类
电工技术 | 164篇 |
综合类 | 10篇 |
化学工业 | 5603篇 |
金属工艺 | 427篇 |
机械仪表 | 559篇 |
建筑科学 | 816篇 |
矿业工程 | 52篇 |
能源动力 | 505篇 |
轻工业 | 5475篇 |
水利工程 | 313篇 |
石油天然气 | 119篇 |
武器工业 | 1篇 |
无线电 | 1048篇 |
一般工业技术 | 4330篇 |
冶金工业 | 14977篇 |
原子能技术 | 67篇 |
自动化技术 | 3572篇 |
出版年
2024年 | 66篇 |
2023年 | 278篇 |
2022年 | 271篇 |
2021年 | 717篇 |
2020年 | 657篇 |
2019年 | 670篇 |
2018年 | 1236篇 |
2017年 | 1208篇 |
2016年 | 1258篇 |
2015年 | 965篇 |
2014年 | 1110篇 |
2013年 | 2307篇 |
2012年 | 1767篇 |
2011年 | 1564篇 |
2010年 | 1273篇 |
2009年 | 1089篇 |
2008年 | 1144篇 |
2007年 | 1050篇 |
2006年 | 673篇 |
2005年 | 561篇 |
2004年 | 536篇 |
2003年 | 520篇 |
2002年 | 433篇 |
2001年 | 323篇 |
2000年 | 263篇 |
1999年 | 596篇 |
1998年 | 4969篇 |
1997年 | 2979篇 |
1996年 | 1827篇 |
1995年 | 1021篇 |
1994年 | 799篇 |
1993年 | 910篇 |
1992年 | 148篇 |
1991年 | 202篇 |
1990年 | 167篇 |
1989年 | 180篇 |
1988年 | 207篇 |
1987年 | 170篇 |
1986年 | 147篇 |
1985年 | 131篇 |
1984年 | 64篇 |
1983年 | 46篇 |
1982年 | 84篇 |
1981年 | 107篇 |
1980年 | 124篇 |
1978年 | 50篇 |
1977年 | 289篇 |
1976年 | 660篇 |
1975年 | 46篇 |
1973年 | 38篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
P de Lonlay JC Fournet J Rahier MS Gross-Morand F Poggi-Travert V Foussier JP Bonnefont MC Brusset F Brunelle JJ Robert C Nihoul-Fékété JM Saudubray C Junien 《Canadian Metallurgical Quarterly》1997,100(4):802-807
Sporadic persistent hyperinsulinemic hypoglycemia of infancy (PHHI) or nesidioblastosis is a heterogeneous disorder characterized by profound hypoglycemia due to inappropriate hypersecretion of insulin. An important diagnostic goal is to distinguish patients with a focal hyperplasia of islet cells of the pancreas (FoPHHI) from those with a diffuse abnormality of islets (DiPHHI) because management strategies differ significantly. 16 infants with sporadic PHHI resistant to diazoxide and who underwent pancreatectomy were investigated. Selective pancreatic venous sampling coupled with peroperative surgical examination and analysis of extemporaneous frozen sections allowed us to identify 10 cases with FoPHHI and 6 cases with DiPHHI. We show here that in cases of FoPHHI, but not those of DiPHHI, there was specific loss of maternal alleles of the imprinted chromosome region 11p15 in cells of the hyperplastic area of the pancreas but not in normal pancreatic cells. This somatic event is consistent with a proliferative monoclonal lesion. It involves disruption of the balance between monoallelic expression of several maternally and paternally expressed genes. Thus, we provide the first molecular explanation of the heterogeneity of sporadic forms of PHHI such that it is possible to perform only partial pancreatectomy, limited to the focal somatic lesion, so as to avoid iatrogenic diabetes in patients with focal adenomatous hyperplasia. 相似文献
72.
The sudden onset of hypertension mandates investigation for secondary causes. We report the case of a young man with a very rare systemic fungal disease that included massive unilateral perirenal adenopathy. Treatment was associated with the abrupt onset of severe hypertension. Imaging studies suggested progressive constriction of one kidney with treatment, presumably as a result of healing adenopathy. We suggest that this case is a new example of hypertension secondary to constrictive perinephritis (Page kidney). 相似文献
73.
TV Perneger P Chopard FP Sarasin JM Gaspoz C Lovis PF Unger AF Junod FA Waldvogel 《Canadian Metallurgical Quarterly》1997,157(13):1495-1500
OBJECTIVE: To identify patient- and admission-related risk factors for a medically inappropriate admission to a department of internal medicine. METHODS: Cross-sectional study of a systematic sample of 500 admissions to the department of internal medicine of an urban teaching hospital. The appropriateness of each admission and reasons for inappropriate admissions were assessed using the Appropriateness Evaluation Protocol. Risk factors included the time (day of week and holidays) and manner (through emergency department or direct admission) of admission, patient age and sex, health status of patient and spouse, living arrangements, formal home care services, and informal support from family or friends. RESULTS: Overall, 76 (15.2%) hospital admissions were rated as medically inappropriate by the Appropriateness Evaluation Protocol. In multivariate analysis, the likelihood of an inappropriate admission was increased by better physical functioning of the patient (odds ratio [OR], 1.5; 95% confidence interval [CI], 1.1-2.1 [for 1 SD in Physical Functioning scores]), lower mental health status of the patient's spouse (OR, 2.6; 95% CI, 1.3-5.6), receipt of informal help from family or friends (OR, 3.3; 95% CI, 1.5-7.2), and hospitalization by one's physician (OR, 3.6; 95% CI, 1.7-7.5). Receiving formal adult home care was not associated with inappropriateness of hospitalization. CONCLUSIONS: Inappropriate admissions to internal medicine wards are determined by a mix of factors, including the patient's health and social environment. In addition, the private practitioners' discretionary ability to hospitalize their patients directly may also favor medically inappropriate admissions. 相似文献
74.
SA Khotimchenko VM Kodentsova IA Alekseeva SG Vlaskina OA Vrzhesinskaia AA Sokol''nikov LA Kharitonchik IP Aleshko-Ozhevskií LV Sheviakova 《Canadian Metallurgical Quarterly》1997,43(3):158-164
Gamma delta T-Cells represent a minor subpopulation of T-lymphocytes in man and their role in normal and diseased human skin is unknown. This article is a comprehensive review of T-lymphocytes bearing the gamma delta T-cell receptor in normal and pathological human skin. Firstly, we have documented the occurrence of gamma delta T-cells in normal skin and in a range of reactive and malignant skin conditions. We have then discussed the experimental findings regarding the repertoire used by gamma delta T-cells in normal human skin and in cutaneous disorders with an increased percentage of gamma delta T-cells. 相似文献
75.
76.
R Jover J Llach JM Bordas A Mas JM Salmerón S Navarro J Terés 《Canadian Metallurgical Quarterly》1997,20(7):344-346
There are evidence indicating that endoscopic retrograde cholangiopancreatography with sphincterotomy (ERCP+S) reduces the rate of complications in patients with severe acute biliary pancreatitis (ABP). The aim of this study was to analyze our experience in the treatment of severe ABP with ERCP+S and compare the evolution of the patients treated early (3 days or less following admission) with those treated late (after the 3rd day). A retrospective review of the clinical histories of the 16 patients with severe ABP treated with ERCP+S over the last two years is presented, analyzing their clinical features on admission and evolution. Biliary stones or biliary sludge was observed in 11 cases (69%). Nine patients had undergone early, and 7 late, ERCP+S. The patients of the latter group presented a greater number of complications during evolution than the former group (43% vs 0%; p = 0.025). The mortality of the patients of the late ERCP+S was also greater although without statistical significance (28.6% vs 0%; p = 0.15). No complication secondary to ERCP+S was detected. These findings confirm the fact that ERCP+S performed early in severe ABP significantly reduces the number of complications and is associated with a lower mortality. 相似文献
77.
78.
G Armengol M Tarkkanen M Virolainen A Forus J Valle T B?hling S Asko-Seljavaara C Blomqvist I Elomaa E Karaharju AH Kivioja MA Siimes E Tukiainen MR Caballín O Myklebost S Knuutila 《Canadian Metallurgical Quarterly》1997,75(10):1403-1409
Comparative genomic hybridization (CGH) was used to detect copy number changes of DNA sequences in the Ewing family of tumours (ET). We analysed 20 samples from 17 patients. Fifteen tumours (75%) showed copy number changes. Gains of DNA sequences were much more frequent than losses, the majority of the gains affecting whole chromosomes or whole chromosome arms. Recurrent findings included copy number increases for chromosomes 8 (seven out of 20 samples; 35%), 1q (five samples; 25%) and 12 (five samples; 25%). The minimal common regions of these gains were the whole chromosomes 8 and 12, and 1q21-22. High-level amplifications affected 8q13-24, 1q and 1q21-22, each once. Southern blot analysis of the specimen with high-level amplification at 1q21-22 showed an amplification of FLG and SPRR3, both mapped to this region. All cases with a gain of chromosome 12 simultaneously showed a gain of chromosome 8. Comparison of CGH findings with cytogenetic analysis of the same tumours and previous cytogenetic reports of ET showed, in general, concordant results. In conclusion, our findings confirm that secondary changes, which may have prognostic significance in ET, are trisomy 8, trisomy 12 and a gain of DNA sequences in 1q. 相似文献
79.
DNA double-strand breaks are very genotoxic lesions that can result in chromosome aberrations. The current view is that DNA double-strand breaks are repaired most efficiently through homologous recombination in yeast and simple end-joining in mammalian cells. However, recent experiments reveal that both repair pathways are conserved from yeast to mammals, including humans. The challenge ahead is to put the different pieces of the jigsaw together into coherent mechanisms for both pathways and to determine their relative contributions to ionizing-radiation resistance and to the prevention of genetic instability and carcinogenesis. 相似文献
80.
AI Quintero Del Río 《Canadian Metallurgical Quarterly》1997,89(1-3):12-14
Motor vehicle accidents are the main cause of death and disability between 1 and 4 years of age. Since 1980 the Academy of Pediatrics has been promoting the correct use of car seats. The major reason that car seats are not fulfilling their full potential is their incorrect or lack of use. In order to evaluate parental knowledge about car seat use for children and their actual use in the population visiting HURRA, a survey was performed which demonstrated that only 57.6% of the parents interviewed had infant car seats and that only 83.3% of owners actually use it. As many as 94.4% had correct knowledge about car seat use, but the majority of correct information was not provided by the medical staff. The majority of parents use seat belts for their own protection but a significantly smaller percentage use car seats for their own children. 相似文献