What is new in bladder cancer imaging

Treatment and prognosis of urinary bladder cancer largely are determined by the tumor stage and presence of metastases. MR imaging and clinical staging complement each other. MR imaging is the most accurate technique for differentiating the various stages of deep tumor infiltration and detection of metastases, whereas clinical staging is the best technique for differentiating between postbiopsy effects and the various stages of superficial tumors. The role of MR imaging in staging of this disease and monitoring of therapy is reviewed and illustrated. Finally, the authors present an overview of current and future applications of this technique.     

An agile manufacturing workcell design

This paper introduces a design for agile manufacturing worked Is intended for light mechanical assembly of products made from similar components (i.e., parts families). We define agile manufacturing as the ability to accomplish rapid changeover from the assembly of one product to the assembly of a different product. Rapid hardware changeover is made possible through the use of robots, flexible part feeders, modular grippers, and modular assembly hardware. The division of assembly, feeding, and unloading tasks between multiple robots is examined with prioritization based upon assembly time. Rapid software changeover will be facilitated by the use of a real-time, object-oriented software environment utilizing graphical simulations for off-line software development. An innovative dual VMEbus controller architecture permits an open software environment while accommodating the closed nature of most commercial robot controllers. These agile features permit new products to be introduced with minimal downtime and system reconfiguration.     

RHEOLOGICAL CHARACTERIZATION OF COMMERCIALLY PROCESSED FLUID MILKS

Flow profiles of commercially processed whole, two-percent, one-percent and nonfat milks with added solids as well as skim milk without added solids were measured using a rotational steady shear viscometer. Also tested were mixtures of concentrated skim milk added to skim milk over a range of 9.7% to 20.2% total solids. A shear rate range of 121 to 486 s^-1 was used with a cone and plate geometry. In all cases, linear plots of shear stress versus shear rate with small nonzero intercepts were obtained.     

Fatigue crack in large-scale tubular joints for offshore structures

Tubular members have been used for constructing offshore structures. Large-scale fatigue tests of welded tubular K-joints under the balanced in-plane bending brace were carried out to investigate the fatigue behavior of API 2W Gr.50 steel produced by POSCO. The experimental results were verified by numerical approaches and compared with the IIW, DnV RP-C203 and API RP 2A-WSD design curves. The test results based on the hot spot stress were in agreement with the design curves. The SCF factor for tubular K-jo...     

Stage IA1 cervical adenocarcinoma: definition and treatment

OBJECTIVE: To propose a definition for stage IA1 cervical adenocarcinoma, based on the International Federation of Gynecology and Obstetrics (FIGO) staging system, and to determine if patients meeting criteria might be candidates for conservative surgery. METHODS: Two hundred women were diagnosed with early-stage cervical adenocarcinoma from 1982 to 1996. Histopathologic sections were reviewed by a gynecologic pathologist. Medical records were reviewed, and patients included in this study had microscopically identifiable lesions, up to 3 mm invasive depth, up to 7 mm tumor width, and negative margins if cone biopsy was performed. RESULTS: Twenty-one patients with microinvasive adenocarcinoma met criteria for FIGO stage IA1 carcinoma of the cervix. The median (range) follow-up was 76 (30-172) months and median (range) patient age was 38 (24-75) years. Definitive treatment included type II or III radical hysterectomy in 16 cases, simple abdominal or vaginal hysterectomy in four cases, and loop electrosurgical excision procedure in one case; one patient received adjuvant pelvic radiation. The histologic subtypes were endocervical adenocarcinoma in 18 cases, adenosquamous carcinoma in two cases, and clear-cell adenocarcinoma in one case. There was no evidence of parametrial invasion or lymph node metastases in any patient who had radical surgery, and there were no disease recurrences. CONCLUSION: Patients with microinvasive adenocarcinoma who met criteria for FIGO stage IA1 cervical carcinoma had disease limited to the cervix, and conservative surgery, such as cone biopsy or simple hysterectomy, might offer them definitive treatment.