Trabeculectomy function after cataract extraction

OBJECTIVE: To examine the effect of cataract extraction (CE) after trabeculectomy on intraocular pressure (IOP) control. DESIGN: Retrospective noncomparative case series. PARTICIPANTS: A total of 115 consecutive patients who underwent extracapsular CE (N = 58) or phacoemulsification (N = 57) with intraocular lens (IOL) placement after trabeculectomy were studied. INTERVENTION: Cataract extraction with IOL after trabeculectomy was performed. MAIN OUTCOME MEASURES: Preoperative, intraoperative, and postoperative factors were evaluated for association with loss of IOP control requiring additional medications, bleb needling, or further glaucoma surgery, using Kaplan-Meier survival analysis and Cox multivariate proportional hazards survival regression. RESULTS: After mean postoperative follow-up of 21.1 +/- 14.3 months, additional glaucoma medication or needling of the filtering bleb to maintain IOP control was required in 35 eyes (30.4%) and was significantly associated with intraoperative iris manipulation and early postoperative peak IOP greater than 25 mmHg. Additional glaucoma surgery was eventually required in 11 eyes (9.6%) and was significantly associated with age of 50 years or younger, preoperative IOP greater than 10 mmHg, and early postoperative peak IOP greater than 25 mmHg. The cumulative proportion of patients who did not require reoperation for glaucoma was 93% and 90% at 1 and 2 years, respectively. The mean IOP at last visit had increased 1.6 mmHg above the pre-CE level and did not vary significantly after the first postoperative month. The median interval from CE to the addition of glaucoma medication or bleb needling was 1.6 months (within 3 months in 20 of 33 eyes) and that from nonsurgical intervention to further glaucoma surgery was 3.6 months (before the 7th postoperative month in 6 of 11 eyes). Of 19 eyes with hypotony (IOP < or = 6 mmHg) before CE, 11 eyes remained hypotonous after CE despite an increase in the mean IOP from 4.6 to 7.5 mmHg. CONCLUSIONS: When CE is performed after trabeculectomy, age of 50 years or younger, preoperative IOP greater than 10 mmHg, intraoperative iris manipulation, and early postoperative IOP greater than 25 mmHg are associated with worsened postoperative IOP control. Most bleb failures occur soon after CE. Resolution of pre-existing hypotony after CE is unpredictable.     

Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA export

The DBP5 gene encodes a putative RNA helicase of unknown function in the yeast Saccharomyces cerevisiae. It is shown here that Dbp5p is an ATP-dependent RNA helicase required for polyadenylated [poly(A)+] RNA export. Surprisingly, Dbp5p is present predominantly, if not exclusively, in the cytoplasm, and is highly enriched around the nuclear envelope. This observation raises the possibility that Dbp5p may play a role in unloading or remodeling messenger RNA particles (mRNPs) upon arrival in the cytoplasm and in coupling mRNP export and translation. The functions of Dbp5p are likely to be conserved, since its potential homologues can be found in a variety of eukaryotic cells.     

航空反潜综合模拟训练系统研究与设计

主要介绍分布式交互仿真技术在航空反潜模拟训练系统设计上的应用,阐述了模拟系统的组成,根据系统的设计要求,构造了分布式仿真对象,并对每个对象构建了仿真模块,最后分析了航空反潜综合训练系统的设计思想。     

使用Python开发跨平台的单词助记程序

介绍使用Python语言开发跨平台的单词助记程序原型的方法,包括安装配置Python环境、单词数据词典文件的格式、程序的主要代码和运行过程。     

Active symbols and internal models: Towards a cognitive connectionism

In the first section of the article, we examine some recent criticisms of the connectionist enterprise: first, that connectionist models are fundamentally behaviorist in nature (and, therefore, non-cognitive), and second that connectionist models are fundamentally associationist in nature (and, therefore, cognitively weak). We argue that, for a limited class of connectionist models (feed-forward, pattern-associator models), the first criticism is unavoidable. With respect to the second criticism, we propose that connectionist modelsare fundamentally associationist but that this is appropriate for building models of human cognition. However, we do accept the point that there are cognitive capacities for which any purely associative model cannot provide a satisfactory account. The implication that we draw from is this is not that associationist models and mechanisms should be scrapped, but rather that they should be enhanced.In the next section of the article, we identify a set of connectionist approaches which are characterized by active symbols — recurrent circuits which are the basis of knowledge representation. We claim that such approaches avoid criticisms of behaviorism and are, in principle, capable of supporting full cognition. In the final section of the article, we speculate at some length about what we believe would be the characteristics of a fully realized active symbol system. This includes both potential problems and possible solutions (for example, mechanisms needed to control activity in a complex recurrent network) as well as the promise of such systems (in particular, the emergence of knowledge structures which would constitute genuine internal models).     

Monitoring children’s developmental progress using augmented toys and activity recognition

Previous research has established the connection between the way in which children interact with objects and the potential early identification of children with autism. Those findings motivate our own work to develop "smart toys," objects embedded with wireless sensors that are safe and enjoyable for very small children, that allow detailed interaction data to be easily recorded. These sensor-enabled toys provide opportunities for autism research by reducing the effort required to collect and analyze a child’s interactions with objects. In the future, such toys may be a useful part of clinical and in-home assessment tools. In this paper, we discuss the design of a collection of smart toys that can be used to automatically characterize the way in which a child is playing. We use statistical models to provide objective, quantitative measures of object play interactions. We also developed a tool to view rich forms of annotated play data for later analysis. We report the results of recognition experiments on more than fifty play sessions conducted with adults and children as well as discuss the opportunities for using this approach to support video annotation and other applications.     

大时延遥操作系统的波变量双边自适应控制

针对通信时延对遥操作系统稳定性和透明性的影响,研究了一种基于双边自适应控制和波变量理论的控制方法。通过设计波控制器保证通信传输模块的无源性,在保证系统稳定的基础上,调节波阻抗系数来提高系统的透明性,并在时延10 s的情况下进行主从端速度、位置和力的跟踪仿真实验,结果表明该方法和已有的双边自适应方法相比既能保证系统稳定且透明性好,达到较好的控制效果。     

基于遗传算法的联合火力WTA问题研究

研究联合火力优化分配问题.联合火力是多种作战力量参战条件下的多武器-多目标对抗.由于火力分配受到多种条件的限制,分配方案又决定作战效果,而武器-目标分配(Weapon Target Assignment,WTA)是多个装备同类型武器的作战单元联合抗击多个目标进行的分配方法.针对WTA问题求解规模大和精度高的特点,传统算法均不能满足速度和精度的要求,在基本遗传算法的基础上,采用精英选择和动态遗传算子的改进算法,避免了过早收敛.利用WTA的数学模型进行仿真.仿真结果验证了算法的有效性.     

热卷箱是提高热连轧线竞争能力的最佳选择

介绍了热卷箱技术的发展及在我国的应用情况。结合“双工位无芯卷取”热卷箱技术在宝钢集团梅山钢铁公司1422mm热轧厂的成功应用，重点介绍了该技术的特点及在解决热轧板带中节能减排、减少氧化铁皮、避免甩尾、稳定精轧轧制及开发高附加值产品等方面的优势；认为其是提高热轧板厂竞争力的最佳选择。